Details of the Drug

General Information of Drug (ID: DMZ2G69)

Drug Name
Navicixizumab
Indication
Disease Entry ICD 11 Status REF
Colorectal cancer 2B91.Z Phase 1 [1]
Fallopian tube cancer 2C74 Phase 1 [2]
Metastatic colorectal cancer 2B91 Phase 1 [2]
Ovarian cancer 2C73 Phase 1 [1]
Peritoneal cavity cancer 2C51.Z Phase 1 [2]
Cross-matching ID
UNII
1W14T9L25W
DrugBank ID
DB12634
TTD ID
D00IVN
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Delta-like protein 4 (DLL4) TTV23LH DLL4_HUMAN Not Available [1]
Vascular endothelial growth factor A (VEGFA) TTOHSBA VEGFA_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Colorectal cancer
ICD Disease Classification 2B91.Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Vascular endothelial growth factor A (VEGFA) DTT VEGFA 3.61E-01 0.15 0.47
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)