Details of the Drug

General Information of Drug (ID: DMZKIE0)

Drug Name
Tolerimab
Synonyms Transplant rejection therapy, Innogenetics; MAbs (organ transplant), Innogenetics; Monoclonal antibodies (organ transplant), Innogenetics; ToleriMab (anti-B7.1/B7.2)
Indication
Disease Entry ICD 11 Status REF
Transplant rejection NE84 Terminated [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
D0V4PH

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Activation B7-1 antigen (CD80) TTFZDNP CD80_HUMAN Not Available [2]
T-lymphocyte activation antigen CD86 (FUN1) TTHGXBU CD86_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Transplant rejection
ICD Disease Classification NE84
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Activation B7-1 antigen (CD80) DTT CD80 6.87E-07 -0.12 -0.3
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011393)
2 US patent application no. 2004,0171,123, Albumin fusion proteins.