Details of the Drug

General Information of Drug (ID: DMZT1T4)

Drug Name

Tocofersolan

Synonyms

TPGS; Tocopherosolan; Vedrop; Tocofersolan (oral liquid pediatric formulation); D-alpha-tocopheryl polyethylene glycol succinate; Tocofersolan (oral liquid pediatric formulation), Orphan Europe; Tocopherosolan (oral liquid pediatric formulation), Orphan Europe; D-alpha-tocopheryl polyethylene glycol succinate, Orphan Europe; TPGS (oral liquid pediatric formulation, vitamin E deficiency), Orphan Europe; Water soluble vitamin E pediatric formulation (cystic fibrosis/chronic cholestasis), Orphan Europe; Tocopherol-PEG-1000 (oral liquid pediatric formulation), Orphan Europe

Indication

Disease Entry	ICD 11	Status	REF
Vitamin E deficiency	5B58	Phase 3	[1]

Affected Organisms

Humans and other mammals

ATC Code

A11HA08: Tocofersolan

A11HA: Other plain vitamin preparations

A11H: OTHER PLAIN VITAMIN PREPARATIONS

A11: VITAMINS

A: ALIMENTARY TRACT AND METABOLISM

Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

Chemical Identifiers

Formula: C35H58O6
Canonical SMILES: CC1=C(C(=C(C2=C1OC(CC2)(C)CCCC(C)CCCC(C)CCCC(C)C)C)OC(=O)CCC(=O)OCCO)C
InChI: InChI=1S/C35H58O6/c1-24(2)12-9-13-25(3)14-10-15-26(4)16-11-20-35(8)21-19-30-29(7)33(27(5)28(6)34(30)41-35)40-32(38)18-17-31(37)39-23-22-36/h24-26,36H,9-23H2,1-8H3/t25-,26-,35+/m1/s1
InChIKey: AOBORMOPSGHCAX-DGHZZKTQSA-N

Cross-matching ID

PubChem CID: 53315106
UNII: O03S90U1F2
DrugBank ID: DB11635
TTD ID: D08CVC

Drug ADMET Endpoint Profile (DAE)^NEW

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References

1	ClinicalTrials.gov (NCT01457690) Study of the Absorption of Vitamin E Water-soluble Form (Pegylated) in the Familial Hypocholesterolemia With Chylomicron Retention. U.S. National Institutes of Health.