Details of the Drug

General Information of Drug (ID: DMZTQD8)

Drug Name
Sirna-027
Indication
Disease Entry ICD 11 Status REF
Exudative age-related macular degeneration 9B78.3Z Phase 1/2 [1]
Neovascular age-related macular degeneration 9B78.3Z Phase 1 [1]
Drug Type
siRNA drug
Cross-matching ID
UNII
86FCX28PTU
DrugBank ID
DB05896
TTD ID
D04WIE

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
VEGFR1 messenger RNA (VEGFR1 mRNA) TT1VAUK VGFR1_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Exudative age-related macular degeneration
ICD Disease Classification 9B78.3Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
VEGFR1 messenger RNA (VEGFR1 mRNA) DTT FLT1 1.64E-05 0.29 0.51
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 2011 Pipeline of Sirna Therapeutics.