Details of the Drug

General Information of Drug (ID: DMZU2G1)

Drug Name

LMP-1/LMP-2 CTLs

Synonyms

Ad5f35LMPd1-2; LMP-1/LMP-2 CTLs, Baylor College of Medicine/NCI; LMP-1/LMP-2 specific cytotoxic T-lymphocytes (gene therapy,nasopharyngeal cancer/lymphoma), Baylor College of Medicine/NCI

Indication

Disease Entry	ICD 11	Status	REF
Lymphoma	2A80-2A86	Phase 1	[1]
------------------------------------------------------------------------------------

Cross-matching ID

TTD ID: D0Z6RW

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Epstein-Barr virus Latent membrane protein 1 (EBV LMP1)	TT0BI4Q	LMP1_EBVG	Modulator	[2]
Epstein-Barr virus Latent membrane protein 2 (EBV LMP2)	TTBK351	LMP2_EBVB9	Modulator	[2]

------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT00062868) LMP-specific T-cells for Patients With Relapsed EBV-positive Lymphoma. U.S. National Institutes of Health.
2	In vivo expansion of LMP 1- and 2-specific T-cells in a patient who received donor-derived EBV-specific T-cells after allogeneic stem cell transplantation. Leuk Lymphoma. 2006 May;47(5):837-42.