Details of the Drug Transporter (DTP)

General Information of Drug Transporter (DTP) (ID: DTFR4NJ)

DTP Name	Potassium channel subfamily K member 9 (KCNK9)
Gene Name	KCNK9
UniProt ID	Q9NPC2 (KCNK9_HUMAN)
VARIDT ID	DTD0546
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Synonyms	Acid-sensitive potassium channel protein TASK-3; TWIK-related acid-sensitive K(+) channel 3; Two pore potassium channel KT3.2; Two pore K(+) channel KT3.2
DTP Family	Voltage-gated Ion Channel (VIC) Superfamily ;
Tissue Specificity	Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung.
Sequence	MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYR QLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ CEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLN LVVLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPRYKADVPDLQSVCSCT CYRSQDYGGRSVAPQNSFSAKLAPHYFHSISYKIEEISPSTLKNSLFPSPISSISPGLHS FTDHQRLMKRRKSV
Function	This transporter is pH-dependent, voltage-insensitive, background potassium channel protein.
TCDB ID	1.A.1.9.11
Gene ID	51305
KEGG Pathway	Aldosterone synthesis and secretion (hsa04925 )
Reactome Pathway	Phase 4 - resting membrane potential (R-HSA-5576886 ) TWIK-releated acid-sensitive K+ channel (TASK) (R-HSA-1299316 )

The Drug Therapeutic Target (DTT) Role of This DTP

DTP DTT Name	TWIK-related acid-sensitive potassium channel 3 (TASK3) DTT Info
DTP DTT Type	Literature-reported