Details of the Drug Transporter (DTP)

General Information of Drug Transporter (DTP) (ID: DTK2TVF)

• DTP Name: Potassium channel subfamily K member 4 (KCNK4)
• Gene Name: KCNK4
• UniProt ID: Q9NYG8 (KCNK4_HUMAN)
• VARIDT ID: DTD0547
• Synonyms: TWIK-related arachidonic acid-stimulated potassium channel protein; TRAAK; Two pore potassium channel KT4.1; Two pore K(+) channel KT4.1
• DTP Family: Voltage-gated Ion Channel (VIC) Superfamily
• Sequence:
  MRSTTLLALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHPCVSDQELGL
  LIKEVADALGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITTIGYGNVALRTDAGRLFC
  IFYALVGIPLFGILLAGVGDRLGSSLRHGIGHIEAIFLKWHVPPELVRVLSAMLFLLIGC
  LLFVLTPTFVFCYMEDWSKLEAIYFVIVTLTTVGFGDYVAGADPRQDSPAYQPLVWFWIL
  LGLAYFASVLTTIGNWLRVVSRRTRAEMGGLTAQAASWTGTVTARVTQRAGPAAPPPEKE
  QPLLPPPPCPAQPLGRPRSPSPPEKAQPPSPPTASALDYPSENLAFIDESSDTQSERGCP
  LPRAPRGRRRPNPPRKPVRPRGPGRPRDKGVPV
• Function: This transporter is voltage-insensitive potassium channel.
• Gene ID: 50801
• Reactome Pathway:
  Phase 4 - resting membrane potential (R-HSA-5576886)
  TWIK related potassium channel (TREK) (R-HSA-1299503)