Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TT3GKN5)

• DTT Name: Lipase unspecific (LIP)
• Gene Name: LIP
• DTT Type: Clinical trial target; [1]
• BioChemical Class: Ester hydrolase
• UniProt ID: NOUNIPROTAC
• TTD ID: T10445

Molecular Interaction Atlas (MIA) of This DTT

1 Clinical Trial Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ApoC-III	DMBRQF5	N. A.	N. A.	Phase 3	[1]

1 Discontinued Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GT-389255	DMLFCNY	Obesity	5B81	Discontinued in Phase 2	[2]

1 Investigative Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Butylphosphonate	DMF5D1N	Discovery agent	N.A.	Investigative	[3]

References

• [1] An ABC of apolipoprotein C-III: a clinically useful new cardiovascular risk factor Int J Clin Pract. 2008 May;62(5):799-809.
• [2] Obesity drugs in clinical development. Curr Opin Investig Drugs. 2006 Apr;7(4):312-8.
• [3] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.