Details of the Drug Therapeutic Target (DTT)
General Information of Drug Therapeutic Target (DTT) (ID: TT4DFM2)
| DTT Name | Serine/arginine-rich splicing factor 12 (Srrp35) | ||||
|---|---|---|---|---|---|
| Synonyms | Splicing factor, arginine/serine-rich 19; Splicing factor, arginine/serine-rich 13B; SRSF12; 35 kDa SR repressor protein | ||||
| Gene Name | SRSF12 | ||||
| DTT Type |
Literature-reported target
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[1] | |||
| BioChemical Class |
Splicing factor SR family
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| UniProt ID | |||||
| TTD ID | |||||
| 3D Structure | |||||
| Sequence |
MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED
VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRT RSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRS RSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQT AKHSHFRSHSRSRSYRHKNSW |
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| Function | Splicing factor that seems to antagonize SR proteins in pre-mRNA splicing regulation. | ||||