Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TT619TC)

DTT Name	Sodium/calcium exchanger (SLC)
Synonyms	NaCaX; Na(+)/Ca(2+) exchanger; Mitochondrial sodium-calcium exchanger
Gene Name	SLC
DTT Type	Clinical trial target	[1]
UniProt ID	NOUNIPROTAC
TTD ID	T72478

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Clinical Trial Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CALDARET HYDRATE	DMDV8MK	Cardiovascular disease	BA00-BE2Z	Phase 2	[1]
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1 Investigative Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SEA-0400	DME69PI	Cerebrovascular ischaemia	8B1Z	Investigative	[2]
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References

1	Caldaret, an intracellular Ca2+ handling modulator, limits infarct size of reperfused canine heart. J Pharmacol Sci. 2007 Feb;103(2):222-33.
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4617).