Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TT6K9BV)

DTT Name	Cdc-like kinase (CLK)
Gene Name	CLK
DTT Type	Clinical trial target	[1]
UniProt ID	CLK1_HUMAN ; CLK2_HUMAN ; CLK3_HUMAN ; CLK4_HUMAN
TTD ID	T51468
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
KEGG Pathway	Legionellosis (hsa05134 )

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Clinical Trial Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SM09419	DM73YG5	Hematologic tumour	2B33.Y	Phase 1	[1]
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References

1	SM09419, a Novel, Small-Molecule CDC-like Kinase (CLK) Inhibitor, Demonstrates Strong Inhibition of the Wnt Signaling Pathway and Antitumor Effects in FMS-like Tyrosine Kinase 3 (FLT3)-Mutant Acute Myeloid Leukemia Models. Blood; 2019,134 (Supplement_1):1377.