Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTAH0B3)

DTT Name Fungal Cell membrane (Fung CM)
Gene Name Fung CM
DTT Type
Successful target
 [1]
UniProt ID
NOUNIPROTAC
TTD ID
T87119

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
2 Approved Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
Haloprogin DMH4IVU Candidiasis 1F23 Approved [2]
Natamycin DMFEHXD Conjunctivitis 9A60 Approved [1]
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References

1 Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane. J Biol Chem. 2008 Mar 7;283(10):6393-401.
2 Haloprogin: mode of action studies in Candida albicans. Can J Microbiol. 1974 Sep;20(9):1241-5.