Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTB0SC6)

DTT Name Potassium (K)
Gene Name K
DTT Type
Successful target
 [1]
UniProt ID
NOUNIPROTAC
TTD ID
T31133

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
2 Approved Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
Patiromer calcium DMMIQ20 Hyperkalemia 5C76 Approved [1]
Sodium zirconium cyclosilicate DMCSLZ4 Hyperkalemia 5C76 Approved [2]
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References

1 Evaluation of the efficacy and safety of RLY5016, a polymeric potassium binder, in a double-blind, placebo-controlled study in patients with chronic heart failure (the PEARL-HF) trial. Eur Heart J. 2011 Apr;32(7):820-8.
2 2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.