Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTBK0PU)

DTT Name	Mycobacterium Cytochrome p450 121 (MycB cyp121)
Synonyms	Cytochrome P450 MT2; Cytochrome P450 121
Gene Name	MycB cyp121
DTT Type	Literature-reported target	[1]
BioChemical Class	Paired donor oxygen oxidoreductase
UniProt ID	CP121_MYCBO
TTD ID	T49627
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
EC Number	EC 1.14.-.-
Sequence	MTATVLLEVPFSARGDRIPDAVAELRTREPIRKVRTITGAEAWLVSSYALCTQVLEDRRF SMKETAAAGAPRLNALTVPPEVVNNMGNIADAGLRKAVMKAITPKAPGLEQFLRDTANSL LDNLITEGAPADLRNDFADPLATALHCKVLGIPQEDGPKLFRSLSIAFMSSADPIPAAKI NWDRDIEYMAGILENPNITTGLMGELSRLRKDPAYSHVSDELFATIGVTFFGAGVISTGS FLTTALISLIQRPQLRNLLHEKPELIPAGVEELLRINLSFADGLPRLATADIQVGDVLVR KGELVLVLLEGANFDPEHFPNPGSIELDRPNPTSHLAFGRGQHFCPGSALGRRHAQIGIE ALLKKMPGVDLAVPIDQLVWRTRFQRRIPERLPVLW
Function	Catalyzes the formation of an intramolecular C-C bond between two tyrosyl carbon atoms of Cyy.

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

2 Investigative Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
4-Iodopyrazole	DMF3CLX	Discovery agent	N.A.	Investigative	[1]
Heme	DMGC287	Discovery agent	N.A.	Investigative	[2]
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References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.