Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTEDCQ0)

DTT Name	Beta-sarcoglycan (SGCB)
Synonyms	Beta-SG; 43 kDa dystrophin-associated glycoprotein; 43DAG; A3b
Gene Name	SGCB
DTT Type	Clinical trial target	[1]
UniProt ID	SGCB_HUMAN
TTD ID	T59382
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MAAAAAAAAEQQSSNGPVKKSMREKAVERRSVNKEHNSNFKAGYIPIDEDRLHKTGLRGR KGNLAICVIILLFILAVINLIITLVIWAVIRIGPNGCDSMEFHESGLLRFKQVSDMGVIH PLYKSTVGGRRNENLVITGNNQPIVFQQGTTKLSVENNKTSITSDIGMQFFDPRTQNILF STDYETHEFHLPSGVKSLNVQKASTERITSNATSDLNIKVDGRAIVRGNEGVFIMGKTIE FHMGGNMELKAENSIILNGSVMVSTTRLPSSSSGDQLGSGDWVRYKLCMCADGTLFKVQV TSQNMGCQISDNPCGNTH
Function	Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
KEGG Pathway	Hypertrophic cardiomyopathy (hsa05410 ) Arrhythmogenic right ventricular cardiomyopathy (hsa05412 ) Dilated cardiomyopathy (hsa05414 ) Viral myocarditis (hsa05416 )

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Clinical Trial Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SRP-9003	DMG8JLC	Limb girdle muscular dystrophy	8C70.4	Phase 1/2	[1]
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References

1	Clinical pipeline report, company report or official report of Sarepta Therapeutics.