Details of the Drug Therapeutic Target (DTT)
General Information of Drug Therapeutic Target (DTT) (ID: TTH29K0)
| DTT Name | Mycobacterium Nicotinate-nucleotide pyrophosphorylase (MycB nadC) | ||||
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| Synonyms | nadC; Quinolinic acid phosphoribosyltransferase; Quinolinate phosphoribosyltransferase [decarboxylating]; QAPRTase | ||||
| Gene Name | MycB nadC | ||||
| DTT Type |
Literature-reported target
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[1] | |||
| BioChemical Class |
Pentosyltransferase
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| UniProt ID | |||||
| TTD ID | |||||
| 3D Structure | |||||
| EC Number |
EC 2.4.2.19
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| Sequence |
MGLSDWELAAARAAIARGLDEDLRYGPDVTTLATVPASATTTASLVTREAGVVAGLDVAL
LTLNEVLGTNGYRVLDRVEDGARVPPGEALMTLEAQTRGLLTAERTMLNLVGHLSGIATA TAAWVDAVRGTKAKIRDTRKTLPGLRALQKYAVRTGGGVNHRLGLGDAALIKDNHVAAAG SVVDALRAVRNAAPDLPCEVEVDSLEQLDAVLPEKPELILLDNFAVWQTQTAVQRRDSRA PTVMLESSGGLSLQTAATYAETGVDYLAVGALTHSVRVLDIGLDM |
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| Function | Involved in the catabolism of quinolinic acid (QA). | ||||
| KEGG Pathway | |||||
Molecular Interaction Atlas (MIA) of This DTT
| Molecular Interaction Atlas (MIA) | ||||||||||||||||||||||||||||||||||||||||||||||
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4 Investigative Drug(s) Targeting This DTT
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