Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTJD1TI)

DTT Name Zinc finger protein OZF (ZNF146)
Synonyms Zinc finger protein 146; Only zinc finger protein; OZF
Gene Name ZNF146
DTT Type
Literature-reported target
 [1]
BioChemical Class
Zinc-finger
UniProt ID
OZF_HUMAN
TTD ID
T86587
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSHLSQQRIYSGENPFACKVCGKVFSHKSNLTEHEHFHTREKPFECNECGKAFSQKQYVI
KHQNTHTGEKLFECNECGKSFSQKENLLTHQKIHTGEKPFECKDCGKAFIQKSNLIRHQR
THTGEKPFVCKECGKTFSGKSNLTEHEKIHIGEKPFKCSECGTAFGQKKYLIKHQNIHTG
EKPYECNECGKAFSQRTSLIVHVRIHSGDKPYECNVCGKAFSQSSSLTVHVRSHTGEKPY
GCNECGKAFSQFSTLALHLRIHTGKKPYQCSECGKAFSQKSHHIRHQKIHTH
Function A nuclear zinc finger protein consisting of a single domain of 10 zinc finger motifs of the Kruppel type, preceded by 10 amino acids. Involved in gene regulation and tumorigenesis.

References

1 The zinc finger protein OZF (ZNF146) is overexpressed in colorectal cancer. J Pathol. 2003 Jun;200(2):177-82.