Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTL7N2W)

DTT Name	B-cell translocation gene 1 protein (BTG1)
Synonyms	Protein BTG1
Gene Name	BTG1
DTT Type	Literature-reported target	[1]
UniProt ID	BTG1_HUMAN
TTD ID	T45357
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MHPFYTRAATMIGEIAAAVSFISKFLRTKGLTSERQLQTFSQSLQELLAEHYKHHWFPEK PCKGSGYRCIRINHKMDPLIGQAAQRIGLSSQELFRLLPSELTLWVDPYEVSYRIGEDGS ICVLYEASPAGGSTQNSTNVQMVDSRISCKEELLLGRTSPSKNYNMMTVSG
Function	Anti-proliferative protein.
KEGG Pathway	RNA degradation (hsa03018 )
Reactome Pathway	FOXO-mediated transcription of cell cycle genes (R-HSA-9617828 )

References

1	MicroRNA 301A Promotes Intestinal Inflammation and Colitis-Associated Cancer Development by Inhibiting BTG1. Gastroenterology. 2017 May;152(6):1434-1448.e15.