Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTLBAP1)

DTT Name	Forkhead box protein C2 (FOXC2)
Synonyms	Transcription factor FKH14; Mesenchyme fork head protein 1; MFH1 protein; Forkheadrelated protein FKHL14; FOXC2
Gene Name	FOXC2
DTT Type	Literature-reported target	[1]
UniProt ID	FOXC2_HUMAN
TTD ID	T46092
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MQARYSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYSAGMGRSYAPYH HHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSI RHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSKEKEER AHLKEPPPAASKGAPATPHLADAPKEAEKKVVIKSEAASPALPVITKVETLSPESALQGS PRSAASTPAGSPDGSLPEHHAAAPNGLPGFSVENIMTLRTSPPGGELSPGAGRAGLVVPP LALPYAAAPPAAYGQPCAQGLEAGAAGGYQCSMRAMSLYTGAERPAHMCVPPALDEALSD HPSGPTSPLSALNLAAGQEGALAATGHHHQHHGHHHPQAPPPPPAPQPQPTPQPGAAAAQ AASWYLNHSGDLNHLPGHTFAAQQQTFPNVREMFNSHRLGIENSTLGESQVSGNASCQLP YRSTPPLYRHAAPYSYDCTKY
Function	Transcriptional activator. Might be involved in the formation of special mesenchymal tissues.

References

1	Forkhead Box Protein C2 (FOXC2) Promotes the Resistance of Human Ovarian Cancer Cells to Cisplatin In Vitro and In Vivo. Cell Physiol Biochem. 2016;39(1):242-52.