Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTMY6L1)

• DTT Name: Fatty acid-binding protein (FABP)
• Synonyms: Fatty acid binding protein
• Gene Name: FABP
• DTT Type: Patented-recorded target; [1]
• UniProt ID: NOUNIPROTAC
• TTD ID: T05034
• KEGG Pathway:
  Alanine, aspartate and glutamate metabolism (hsa00250)
  Cysteine and methionine metabolism (hsa00270)
  Arginine and proline metabolism (hsa00330)
  Tyrosine metabolism (hsa00350)
  Phenylalanine metabolism (hsa00360)
  Phenylalanine, tyrosine and tryptophan biosynthesis (hsa00400)
  Metabolic pathways (hsa01100)
  Biosynthesis of antibiotics (hsa01130)
  Carbon metabolism (hsa01200)
  2-Oxocarboxylic acid metabolism (hsa01210)
  Biosynthesis of amino acids (hsa01230)
  Fat digestion and absorption (hsa04975)
• Reactome Pathway:
  Amino acid synthesis and interconversion (transamination) (R-HSA-70614)
  Gluconeogenesis (R-HSA-70263)

Molecular Interaction Atlas (MIA) of This DTT

19 Patented Agent(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID27109571-Compound-1	DMW2N5D	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-2	DMTD1X8	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-3	DMDXMH9	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-32	DM4IS6Q	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-33	DMGR2JC	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-34	DM5OXUK	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-35	DMGV4PT	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-36	DMCJ48G	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-37	DMJCAOD	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-38	DMRQHDF	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-39	DMBHJDR	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-4	DMYRG0Q	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-40	DMQ83EV	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-41	DMY4IAV	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-42	DMZOI3K	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-43	DMYZ42W	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-44	DM3AUZS	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-5	DMOZKAH	N. A.	N. A.	Patented	[1]
PMID27109571-Compound-6	DMPHMTR	N. A.	N. A.	Patented	[1]

1 Discontinued Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BVT-24834	DMHLUFN	Obesity	5B81	Terminated	[2]

References

• [1] Fatty acid binding protein (FABP) inhibitors: a patent review (2012-2015).Expert Opin Ther Pat. 2016 Jul;26(7):767-76.
• [2] Fragment-Based Drug Discovery: A Practical Approach. Edward Zartler, Michael Shapiro, 2008. Page(84).