Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTPFZJ1)

DTT Name Vasopressin V1 receptor (V1R)
Synonyms Vasopressin receptor 1; ADH V1 receptor
Gene Name V1R
DTT Type
Successful target
 [1]
UniProt ID
NOUNIPROTAC
TTD ID
T29999

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
3 Approved Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lypressin DM154EB Amnesia MB21.1 Approved [1]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [2]
Mozavaptan DMZ905C Hyponatraemia 5C72 Approved [3]
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1 Discontinued Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
OPC-21268 DM7OVMH Cardiac disease BA00-BE2Z Discontinued in Phase 2 [3]
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References

1 Human pain thresholds after the application of lypressin, a vasopressin analogue. Pharmacol Toxicol. 1987 Jul;61(1):16-9.
2 Evidence in hyponatremia related to inappropriate secretion of ADH that V1 receptor stimulation contributes to the increase in renal uric acid clearance. J Am Soc Nephrol. 1996 May;7(5):805-10.
3 Vasopressin (ADH). Nippon Rinsho. 1992 Dec;50(12):2893-900.