Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTPQE9F)

DTT Name Early activation antigen CD69 (CD69)
Synonyms MLR3; Leukocyte surface antigen Leu23; GP32/28; Early Tcell activation antigen p60; EA1; Ctype lectin domain family 2 member C; CD69; BLAC/P26; Activation inducer molecule
Gene Name CD69
DTT Type
Literature-reported target
 [1]
UniProt ID
CD69_HUMAN
TTD ID
T48780
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSSENCFVAENSSLHPESGQENDATSPHFSTRHEGSFQVPVLCAVMNVVFITILIIALIA
LSVGQYNCPGQYTFSMPSDSHVSSCSEDWVGYQRKCYFISTVKRSWTSAQNACSEHGATL
AVIDSEKDMNFLKRYAGREEHWVGLKKEPGHPWKWSNGKEFNNWFNVTGSDKCVFLKNTE
VSSMECEKNLYWICNKPYK
Function Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.

References

1 Is CD69 an effective brake to control inflammatory diseases Trends Mol Med. 2013 Oct;19(10):625-32.