Details of the Drug Therapeutic Target (DTT)
General Information of Drug Therapeutic Target (DTT) (ID: TTPXTVS)
| DTT Name | Entamoeba Cysteine proteinase CP4 (Eh CP4) | ||||
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| Synonyms | Entamoeba Cysteine proteinase CP4; Cysteine proteinase | ||||
| Gene Name | Eh CP4 | ||||
| DTT Type |
Literature-reported target
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[1] | |||
| UniProt ID | |||||
| TTD ID | |||||
| EC Number |
EC 3.4.22.35
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| Sequence |
FVAAATAIDFKSWAAKNNKHFTAVEALRRRAIFNMNAKFVAKFNKANSFELSVDGPFAAM
TNEEYNHLLRVHETEAAADSVYDNTIITASSKDWRAEGKVTPVRDQGNCGSCYSFSSLAV LESRLLIAGSKYNQNNQDLSEQQIVDCSTANNGCNGGSLSATYLYVKNNGVTDEASYPYT ATKGTCKAFTPKVQTTGLTHVTPNEDALTSALEQGPVAVCIDAGKASFQLYKSGVYDEPK CSKTVNHGVAAVGYGTQDGKDYYIVKNSWGTSWGDKGYILMSRNKNNQCAIASVAYFPNG AHDAN |
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| Function | Plays a key role in disrupting the colonic epithelial barrier and the innate host immune response during invasion of E. histolytica, the protozoan cause of human amebiasis. | ||||
Molecular Interaction Atlas (MIA) of This DTT
| Molecular Interaction Atlas (MIA) | ||||||||||||||||||||||||||||
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1 Investigative Drug(s) Targeting This DTT
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