Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTS2TGF)

DTT Name	Interferon-omega (IFNW1)
Synonyms	Interferon omega1; Interferon omega-1; Interferon alphaII1; Interferon alpha-II-1
Gene Name	IFNW1
DTT Type	Clinical trial target	[1]
BioChemical Class	Cytokine: interferon
UniProt ID	IFNW1_HUMAN
TTD ID	T11005
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MALLFPLLAALVMTSYSPVGSLGCDLPQNHGLLSRNTLVLLHQMRRISPFLCLKDRRDFR FPQEMVKGSQLQKAHVMSVLHEMLQQIFSLFHTERSSAAWNMTLLDQLHTGLHQQLQHLE TCLLQVVGEGESAGAISSPALTLRRYFQGIRVYLKEKKYSDCAWEVVRMEIMKSLFLSTN MQERLRSKDRDLGSS
Function	extracellular space, cytokine activity, cytokine receptor binding, type I interferon receptor binding, adaptive immune response, B cell differentiation, B cell proliferation, cell cycle arrest, cytokine-mediated signaling pathway, humoral immune response.
KEGG Pathway	Cytokine-cytokine receptor interaction (hsa04060 ) RIG-I-like receptor signaling pathway (hsa04622 ) Jak-STAT signaling pathway (hsa04630 )

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Clinical Trial Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ITCA-638	DMDZWPL	Hepatitis C virus infection	1E51.1	Phase 2	[1]
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References

1	Interferons and viral infections. Biofactors. 2009 Jan-Feb;35(1):14-20.