Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTT04VN)

DTT Name Adrenergic neuron (AD neuro)
Gene Name AD neuro
DTT Type
Successful target
 [1]
UniProt ID
NOUNIPROTAC
TTD ID
T74654

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
2 Approved Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
Debrisoquin DMC50ME Hypertension BA00-BA04 Approved [2]
Guanethidine DM9NSWT Moderate and severe hypertension BA00.Z Approved [1]
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References

1 Characterization of bradykinin-induced endothelium-independent contraction in equine basilar artery. J Vet Pharmacol Ther. 2009 Jun;32(3):264-70.
2 Guanethidine and related agents. 3. Antagonism by drugs which inhibit the norepinephrine pump in man. J Clin Invest. 1970 Aug;49(8):1596-604.