Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTV2CN0)

DTT Name Interferon receptor (IFNR)
Synonyms Interferon receptor
Gene Name IFNR
DTT Type
Clinical trial target
 [1]
UniProt ID
NOUNIPROTAC
TTD ID
T59735

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
2 Clinical Trial Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
HDV-interferon DMAX632 Hepatitis C virus infection 1E51.1 Phase 2 [1]
Z-100 DM1H75D Human immunodeficiency virus infection 1C62 Phase 1 [2]
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2 Discontinued Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bropirimine DMMT1YQ Virus infection 1A24-1D9Z Discontinued in Phase 3 [3]
Omniferon DMSKAGP Solid tumour/cancer 2A00-2F9Z Terminated [4]
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References

1 Interferon in HDV infection. Antiviral Res. 1994 Jul;24(2-3):165-74.
2 Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages. J Gen Virol. 2004 Sep;85(Pt 9):2603-13.
3 Comparison between circulating interferon and drug levels following administration of 2-amino-5-bromo-6-phenyl-4(3H)-pyrimidinone (ABPP) to different animal species. J Interferon Res. 1982;2(3):317-27.
4 US patent application no. 2004,0229,936, Treatment of hepatitis c virus infection with sesquiterpene lactones.