Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTVFR2S)

DTT Name	Vibrio TCP pilus virulence regulatory protein (Vibrio tcpN)
Gene Name	Vibrio tcpN
DTT Type	Preclinical target	[1]
UniProt ID	TCPN_VIBCH
TTD ID	T56824
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MIGKKSFQTNVYRMSKFDTYIFNNLYINDYKMFWIDSGIAKLIDKNCLVSYEINSSSIIL LKKNSIQRFSLTSLSDENINVSVITISDSFIRSLKSYILGDLMIRNLYSENKDLLLWNCE HNDIAVLSEVVNGFREINYSDEFLKVFFSGFFSKVEKKYNSIFITDDLDAMEKISCLVKS DITRNWRWADICGELRTNRMILKKELESRGVKFRELINSIRISYSISLMKTGEFKIKQIA YQSGFASVSYFSTVFKSTMNVAPSEYLFMLTGVAEK
Function	Probable regulatory protein for the tcp operon.
KEGG Pathway	Biofilm formation - Vibrio cholerae (vch05111 )
BioCyc Pathway	VCHO:VC0838-MON

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Preclinical Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Virstatin	DMQG2EY	Acinetobacter baumannii infection	CA40.0Y	Preclinical	[1]
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References

1	Virstatin inhibits dimerization of the transcriptional activator ToxT. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2372-7.