Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTVH0YQ)

• DTT Name: Mycobacterium Fusion protein Rv2608-Rv3619-Rv3620-Rv1813 (MycB antigens)
• Synonyms: Mycobacterium Fusion protein PPE42-esxV-esxW-MTY16F9.01
• Gene Name: MycB antigens
• DTT Type: Clinical trial target; [1]
• UniProt ID: PPE42_MYCTU-ESXV_MYCTU-ESXW_MYCTU-Y1813_MYCTU
• TTD ID: T86992
• Sequence:
  MTSRFMTDPHAMRDMAGRFEVHAQTVEDEARRMWASAQNISGAGWSGMAEATSLDTMTQM
  NQAFRNIVNMLHGVRDGLVRDANNYEQQEQASQQILSSMTINYQFGDVDAHGAMIRAQAG
  SLEAEHQAIISDVLTASDFWGGAGSAACQGFITQLGRNFQVIYEQANAHGQKVQAAGNNM
  AQTDSAVGSSWAMNFAVLPPEVNSARIFAGAGLGPMLAAASAWDGLAEELHAAAGSFASV
  TTGLAGDAWHGPASLAMTRAASPYVGWLNTAAGQAAQAAGQARLAASAFEATLAATVSPA
  MVAANRTRLASLVAANLLGQNAPAIAAAEAEYEQIWAQDVAAMFGYHSAASAVATQLAPI
  QEGLQQQLQNVLAQLASGNLGSGNVGVGNIGNDNIGNANIGFGNRGDANIGIGNIGDRNL
  GIGNTGNWNIGIGITGNGQIGFGKPANPDVLVVGNGGPGVTALVMGGTDSLLPLPNIPLL
  EYAARFITPVHPGYTATFLETPSQFFPFTGLNSLTYDVSVAQGVTNLHTAIMAQLAAGNE
  VVVFGTSQSATIATFEMRYLQSLPAHLRPGLDELSFTLTGNPNRPDGGILTRFGFSIPQL
  GFTLSGATPADAYPTVDYAFQYDGVNDFPKYPLNVFATANAIAGILFLHSGLIALPPDLA
  SGVVQPVSSPDVLTTYILLPSQDLPLLVPLRAIPLLGNPLADLIQPDLRVLVELGYDRTA
  HQDVPSPFGLFPDVDWAEVAADLQQGAVQGVNDALSGLGLPPPWQPALPRLFMITNLRRR
  TAMAAAGLGAALGLGILLVPTVDAHLANGSMSEVMMSEIAGLPIPPIIHYGAIAYAPSGA
  SGKAWHQRTPARAEQVALEKCGDKTCKVVSRFTRCGAVAYNGSKYQGGTGLTRRAAEDDA
  VNRLEGGRIVNWACN
• Function: Invovled in immune response.

Molecular Interaction Atlas (MIA) of This DTT

1 Clinical Trial Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ID-93/GLA-SE	DM7XIAJ	Tuberculosis	1B10-1B1Z	Phase 2	[1]

References

• [1] US patent application no. US20150182612 A1.