Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTVX9SH)

DTT Name	Trace amine receptor 3 (TAAR3)
Synonyms	hTaar3; TaR-3; TAAR3; Putative trace amine-associated receptor 3; GPR57; G-protein coupled receptor 57
Gene Name	TAAR3P
DTT Type	Literature-reported target	[1]
UniProt ID	TAAR3_HUMAN
TTD ID	T82922
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MDLTYIPEDLSSCPKFVNKILSSHQPLFSCPGDNVFGYDWSHDYPLFGNLVIMVSISHFK QLHSPTNFLILSMATTDFLLGFVIMPYSIMRSVESCWYFGDGFCKFHTSFDMMLRLTSIF HLCSIAIDRFYAVCYPLHYTTKMTNSTIKQLLAFCWSVPALFSFGLVLSEADVSGMQSYK ILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSKQHARVISHVPENTKG AVKKHLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPILILDLLVWLRYF NSTCNPLIHGFFNPWFQKAFKYIVSGKIFSSHSETANLFPEAH
Function	G protein-coupled receptor activity, trace-amine receptor activity, sensory perception of chemical stimulus
Reactome Pathway	G alpha (s) signalling events (R-HSA-418555 ) ADORA2B mediated anti-inflammatory cytokines production (R-HSA-9660821 ) Amine ligand-binding receptors (R-HSA-375280 )

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Investigative Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
isoamylamine	DMTEDHP	Discovery agent	N.A.	Investigative	[1]
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References

1	A second class of chemosensory receptors in the olfactory epithelium. Nature. 2006 Aug 10;442(7103):645-50.