Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTZ6I58)

DTT Name Homeobox protein Hox-B13 (HOXB13)
Synonyms Hoxb-13; HOXB13
Gene Name HOXB13
DTT Type
Literature-reported target
 [1]
UniProt ID
HXB13_HUMAN
TTD ID
T84032
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEPGNYATLDGAKDIEGLLGAGGGRNLVAHSPLTSHPAAPTLMPAVNYAPLDLPGSAEPP
KQCHPCPGVPQGTSPAPVPYGYFGGGYYSCRVSRSSLKPCAQAATLAAYPAETPTAGEEY
PSRPTEFAFYPGYPGTYQPMASYLDVSVVQTLGAPGEPRHDSLLPVDSYQSWALAGGWNS
QMCCQGEQNPPGPFWKAAFADSSGQHPPDACAFRRGRKKRIPYSKGQLRELEREYAANKF
ITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKNSATP
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

References

1 Androgen-independent expression of hoxb-13 in the mouse prostate. Prostate. 1999 Nov 1;41(3):203-7.