Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE2HB58)

• DME Name: Nicotinate-nucleotide adenylyltransferase 2 (NMNAT2) DME Info
• Gene Name: NMNAT2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	8.13E-01	1.72E-02	1.02E-01
Alopecia	ED70	Skin from scalp	1.76E-01	1.27E-01	3.36E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.50E-08	-9.26E-01	-1.02E+00
Ankylosing spondylitis	FA92.0	Pheripheral blood	9.06E-01	-9.09E-02	-6.31E-01
Aortic stenosis	BB70	Calcified aortic valve	6.39E-01	2.27E-01	3.98E-01
Apnea	7A40	Hyperplastic tonsil	6.91E-01	-4.22E-02	-2.64E-01
Arthropathy	FA00-FA5Z	Peripheral blood	4.89E-01	1.63E-02	1.47E-01
Asthma	CA23	Nasal and bronchial airway	3.01E-04	-9.44E-02	-2.25E-01
Atopic dermatitis	EA80	Skin	2.56E-01	-1.59E-02	-1.80E-01
Autism	6A02	Whole blood	7.33E-02	-6.19E-02	-2.96E-01
Autoimmune uveitis	9A96	Peripheral monocyte	4.55E-02	-1.17E-01	-8.93E-01
Autosomal dominant monocytopenia	4B04	Whole blood	9.25E-01	1.07E-01	8.06E-01
Bacterial infection of gingival	1C1H	Gingival tissue	6.39E-02	6.06E-02	2.30E-01
Batten disease	5C56.1	Whole blood	7.37E-01	-1.64E-02	-1.99E-01
Behcet's disease	4A62	Peripheral blood	8.94E-01	-3.98E-02	-2.80E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	6.82E-01	-5.43E-02	-1.33E-01
Bladder cancer	2C94	Bladder tissue	1.41E-05	6.78E-01	3.12E+00
Breast cancer	2C60-2C6Z	Breast tissue	2.14E-58	-5.55E-01	-1.39E+00
Cardioembolic stroke	8B11.20	Whole blood	6.53E-06	2.68E-01	1.17E+00
Cervical cancer	2C77	Cervical tissue	8.44E-01	7.92E-02	4.23E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.49E-01	-1.81E-02	-8.17E-02
Chronic hepatitis C	1E51.1	Whole blood	7.65E-01	-2.12E-02	-1.33E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.21E-01	5.99E-02	4.14E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	3.72E-04	1.28E-01	8.26E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	6.27E-01	-8.51E-02	-7.93E-01
Colon cancer	2B90	Colon tissue	8.36E-15	1.51E-01	6.69E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	9.31E-01	6.42E-03	3.04E-02
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	8.32E-01	2.45E-02	1.78E-01
Endometriosis	GA10	Endometrium tissue	4.79E-01	1.05E-01	3.26E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.38E-02	-8.16E-02	-6.58E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.39E-03	-2.96E-01	-1.71E+00
Gastric cancer	2B72	Gastric tissue	5.70E-01	-2.79E-01	-3.87E-01
Glioblastopma	2A00.00	Nervous tissue	3.51E-102	-1.66E+00	-1.54E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	1.64E-01	-1.59E-01	-1.09E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	9.80E-03	8.60E-01	1.47E+00
Head and neck cancer	2D42	Head and neck tissue	1.04E-03	1.06E-01	5.53E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.78E-01	-7.13E-01	-7.93E-01
Huntington's disease	8A01.10	Whole blood	3.16E-02	9.32E-02	1.07E+00
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.37E-01	1.57E-01	6.68E-01
Immunodeficiency	4A00-4A20	Peripheral blood	2.49E-01	8.56E-02	1.37E+00
Influenza	1E30	Whole blood	3.52E-01	2.38E-01	1.14E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.20E-01	1.63E-01	1.15E+00
Intracranial aneurysm	8B01.0	Intracranial artery	4.11E-02	-6.67E-01	-9.93E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	7.83E-02	1.25E-01	3.82E-01
Ischemic stroke	8B11	Peripheral blood	5.77E-01	9.09E-03	6.52E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.28E-04	9.61E-02	5.53E-01
Lateral sclerosis	8B60.4	Skin	6.86E-01	3.41E-01	5.15E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	9.49E-01	5.16E-02	8.78E-02
Liver cancer	2C12.0	Liver tissue	3.75E-02	-9.99E-02	-6.05E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.44E-01	8.04E-02	6.23E-01
Lung cancer	2C25	Lung tissue	1.33E-30	7.81E-02	4.15E-01
Lupus erythematosus	4A40	Whole blood	1.99E-01	-9.04E-02	-2.25E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	9.21E-01	-5.83E-02	-1.53E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.52E-02	7.38E-02	3.79E-01
Melanoma	2C30	Skin	8.03E-01	-5.14E-02	-1.28E-01
Multiple myeloma	2A83.1	Peripheral blood	1.89E-01	2.48E-02	1.92E-01
Multiple myeloma	2A83.1	Bone marrow	5.42E-03	-2.89E-01	-1.51E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.94E-01	1.73E-01	8.90E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	7.50E-01	4.72E-03	2.20E-02
Myelofibrosis	2A20.2	Whole blood	3.47E-02	-1.23E-01	-1.47E+00
Myocardial infarction	BA41-BA50	Peripheral blood	3.81E-01	1.88E-01	4.41E-01
Myopathy	8C70.6	Muscle tissue	4.92E-01	-8.93E-02	-5.82E-01
Neonatal sepsis	KA60	Whole blood	6.60E-10	1.46E-01	9.73E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.33E-01	1.37E-02	5.72E-02
Non-alcoholic fatty liver disease	DB92	Liver tissue	4.06E-01	-1.03E-02	-7.26E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.74E-01	8.12E-02	3.03E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.97E-01	1.65E-01	1.06E+00
Oral cancer	2B6E	Oral tissue	8.71E-01	-4.03E-02	-1.61E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	7.18E-01	-6.51E-02	-5.65E-01
Osteoporosis	FB83.1	Bone marrow	6.64E-01	9.80E-03	5.69E-02
Ovarian cancer	2C73	Ovarian tissue	1.81E-04	1.84E-01	6.79E-01
Pancreatic cancer	2C10	Pancreas	1.95E-01	-1.33E-01	-4.18E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	5.98E-02	-6.92E-01	-1.04E+00
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	8.56E-01	-1.65E-02	-1.37E-01
Pituitary cancer	2D12	Pituitary tissue	4.17E-01	2.04E-01	4.72E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	4.48E-02	2.47E-01	8.06E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	5.67E-01	3.83E-02	2.99E-01
Polycythemia vera	2A20.4	Whole blood	1.94E-03	-3.86E-02	-4.09E-01
Pompe disease	5C51.3	Biceps muscle	4.34E-01	1.48E-01	6.81E-01
Preterm birth	KA21.4Z	Myometrium	5.32E-01	-2.98E-02	-1.63E-01
Prostate cancer	2C82	Prostate	1.11E-03	-5.19E-01	-1.41E+00
Psoriasis	EA90	Skin	2.69E-04	-1.25E-01	-5.39E-01
Rectal cancer	2B92	Rectal colon tissue	7.88E-01	6.35E-02	3.04E-01
Renal cancer	2C90-2C91	Kidney	1.13E-01	-3.54E-02	-1.55E-01
Retinoblastoma	2D02.2	Uvea	5.00E-06	-8.57E-01	-2.17E+00
Rheumatoid arthritis	FA20	Synovial tissue	4.67E-01	-1.77E-02	-1.54E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	4.21E-01	-2.24E-02	-2.01E-01
Schizophrenia	6A20	Prefrontal cortex	9.41E-02	-2.54E-01	-1.81E-01
Schizophrenia	6A20	Superior temporal cortex	5.06E-01	1.40E-02	2.75E-02
Scleroderma	4A42.Z	Whole blood	8.51E-01	-1.54E-02	-1.06E-01
Seizure	8A60-8A6Z	Whole blood	3.86E-01	-3.83E-02	-2.75E-01
Sensitive skin	EK0Z	Skin	7.69E-01	-1.67E-02	-1.08E-01
Sepsis with septic shock	1G41	Whole blood	4.06E-30	2.23E-01	1.22E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.24E-01	7.42E-01	1.41E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	7.79E-01	3.28E-02	2.55E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	8.35E-01	-8.58E-02	-4.29E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.59E-01	-4.03E-02	-2.29E-01
Skin cancer	2C30-2C3Z	Skin	5.35E-03	-2.00E-01	-8.32E-01
Thrombocythemia	3B63	Whole blood	9.72E-01	-2.41E-02	-2.55E-01
Thrombocytopenia	3B64	Whole blood	4.26E-01	2.38E-01	1.03E+00
Thyroid cancer	2D10	Thyroid	1.52E-06	-6.28E-01	-1.15E+00
Tibial muscular dystrophy	8C75	Muscle tissue	7.71E-01	2.27E-02	1.53E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	4.71E-03	-1.48E+00	-2.83E+00
Type 2 diabetes	5A11	Liver tissue	3.28E-01	-7.29E-02	-5.80E-01
Ureter cancer	2C92	Urothelium	7.89E-01	-6.63E-03	-3.35E-02
Uterine cancer	2C78	Endometrium tissue	5.47E-01	-2.56E-02	-1.27E-01
Vitiligo	ED63.0	Skin	1.26E-01	-5.68E-01	-1.20E+00