Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE2JP1Y)

• DME Name: Aldehyde dehydrogenase 1 (ALDH1) DME Info
• Gene Name: ALDH1A1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	5.29E-41	-1.95E+00	-2.76E+00
Alopecia	ED70	Skin from scalp	2.70E-02	2.37E-01	4.16E-01
Alzheimer's disease	8A20	Entorhinal cortex	8.91E-01	-1.12E-01	-1.37E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	5.53E-01	3.02E-02	4.50E-02
Aortic stenosis	BB70	Calcified aortic valve	3.51E-02	-1.31E+00	-1.08E+00
Apnea	7A40	Hyperplastic tonsil	2.27E-01	1.18E+00	2.81E+00
Arthropathy	FA00-FA5Z	Peripheral blood	8.01E-01	-7.01E-02	-2.17E-01
Asthma	CA23	Nasal and bronchial airway	9.11E-01	-1.75E-02	-4.27E-02
Atopic dermatitis	EA80	Skin	8.52E-11	-1.27E+00	-2.23E+00
Autism	6A02	Whole blood	1.53E-01	1.34E-01	2.33E-01
Autoimmune uveitis	9A96	Peripheral monocyte	2.31E-01	1.92E-01	9.72E-02
Autosomal dominant monocytopenia	4B04	Whole blood	1.27E-01	-1.38E-01	-2.86E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.87E-02	7.74E-01	6.85E-01
Batten disease	5C56.1	Whole blood	4.12E-01	-1.60E-01	-3.44E-01
Behcet's disease	4A62	Peripheral blood	5.12E-01	2.61E-01	5.39E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.09E-01	-8.44E-02	-2.40E-01
Bladder cancer	2C94	Bladder tissue	1.57E-20	-3.88E+00	-1.28E+01
Breast cancer	2C60-2C6Z	Breast tissue	1.36E-79	-2.87E+00	-1.90E+00
Cardioembolic stroke	8B11.20	Whole blood	1.83E-01	-9.69E-02	-1.79E-01
Cervical cancer	2C77	Cervical tissue	6.60E-01	-3.40E-01	-2.64E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.07E-01	-1.93E-02	-1.17E-02
Chronic hepatitis C	1E51.1	Whole blood	7.00E-01	-8.72E-01	-5.10E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	3.14E-01	-9.64E-02	-2.24E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	7.30E-02	-8.54E-02	-2.82E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	3.07E-02	-1.24E+00	-1.78E+00
Colon cancer	2B90	Colon tissue	1.73E-76	-1.60E+00	-2.63E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.81E-03	4.93E-01	2.32E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	2.94E-01	-9.50E-02	-5.55E-01
Endometriosis	GA10	Endometrium tissue	6.20E-01	-6.06E-01	-2.44E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	5.86E-02	-1.32E-01	-1.68E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.49E-04	2.38E+00	1.75E+00
Gastric cancer	2B72	Gastric tissue	1.34E-01	-1.77E+00	-1.39E+00
Glioblastopma	2A00.00	Nervous tissue	3.45E-61	-1.72E+00	-1.32E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	3.01E-01	-2.85E+00	-1.60E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.43E-01	-5.13E-01	-4.47E-01
Head and neck cancer	2D42	Head and neck tissue	2.73E-35	-4.23E+00	-2.14E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	2.13E-02	-3.39E-01	-7.65E-01
Huntington's disease	8A01.10	Whole blood	6.42E-01	-4.02E-01	-4.83E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	8.77E-01	-2.24E-01	-2.74E-01
Immunodeficiency	4A00-4A20	Peripheral blood	8.35E-01	2.66E-02	3.32E-01
Influenza	1E30	Whole blood	8.22E-01	1.65E-01	3.71E-01
Interstitial cystitis	GC00.3	Bladder tissue	1.54E-03	-9.51E-01	-2.90E+00
Intracranial aneurysm	8B01.0	Intracranial artery	9.39E-03	-1.09E+00	-1.14E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.24E-02	-1.06E-01	-3.82E-01
Ischemic stroke	8B11	Peripheral blood	2.16E-01	-1.64E-01	-3.08E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	4.04E-09	-5.83E-01	-7.74E-01
Lateral sclerosis	8B60.4	Skin	3.86E-01	-4.53E-02	-1.52E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	2.42E-01	-2.40E-01	-7.51E-01
Liver cancer	2C12.0	Liver tissue	6.92E-01	1.79E-02	1.95E-02
Liver failure	DB99.7-DB99.8	Liver tissue	7.76E-01	5.55E-01	7.57E-01
Lung cancer	2C25	Lung tissue	1.32E-86	-1.48E+00	-2.67E+00
Lupus erythematosus	4A40	Whole blood	2.24E-03	8.89E-01	5.91E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	2.42E-01	-1.13E-01	-3.27E-01
Major depressive disorder	6A70-6A7Z	Whole blood	5.53E-01	-2.11E-02	-4.30E-02
Melanoma	2C30	Skin	2.29E-01	-2.61E-02	-1.54E-02
Multiple myeloma	2A83.1	Peripheral blood	4.04E-01	4.26E-02	1.28E-01
Multiple myeloma	2A83.1	Bone marrow	6.75E-03	-1.25E+00	-1.29E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	5.83E-02	4.26E-01	6.92E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	3.13E-03	-2.31E-01	-3.62E-01
Myelofibrosis	2A20.2	Whole blood	7.97E-02	-2.22E-01	-4.17E-01
Myocardial infarction	BA41-BA50	Peripheral blood	2.87E-04	7.31E-01	6.74E-01
Myopathy	8C70.6	Muscle tissue	8.64E-02	4.27E-01	7.20E-01
Neonatal sepsis	KA60	Whole blood	5.17E-06	-8.01E-01	-1.19E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.81E-09	-4.90E+00	-5.98E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.68E-01	2.79E-01	7.58E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.67E-01	-1.11E-01	-2.27E-01
Olive pollen allergy	CA08.00	Peripheral blood	5.77E-02	3.33E-01	1.16E+00
Oral cancer	2B6E	Oral tissue	2.70E-01	-4.27E-01	-2.05E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	1.41E-01	-1.45E+00	-7.36E-01
Osteoporosis	FB83.1	Bone marrow	9.19E-01	-9.71E-03	-7.21E-02
Ovarian cancer	2C73	Ovarian tissue	1.12E-05	-3.34E+00	-3.66E+00
Pancreatic cancer	2C10	Pancreas	5.26E-01	2.64E-01	2.87E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	2.84E-03	-1.20E+00	-8.60E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	3.50E-02	-4.65E-01	-4.39E-01
Pituitary cancer	2D12	Pituitary tissue	5.74E-08	-2.66E+00	-7.30E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	4.08E-04	-2.03E+00	-5.09E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	6.50E-01	-1.31E-01	-3.27E-01
Polycythemia vera	2A20.4	Whole blood	3.66E-04	-2.55E-01	-5.07E-01
Pompe disease	5C51.3	Biceps muscle	2.57E-01	-2.56E-01	-1.12E+00
Preterm birth	KA21.4Z	Myometrium	4.89E-01	1.75E-01	1.17E-01
Prostate cancer	2C82	Prostate	9.39E-01	3.56E-01	3.91E-01
Psoriasis	EA90	Skin	5.09E-06	-4.25E-01	-5.23E-01
Rectal cancer	2B92	Rectal colon tissue	8.07E-07	-1.32E+00	-3.76E+00
Renal cancer	2C90-2C91	Kidney	1.12E-02	9.46E-03	1.76E-02
Retinoblastoma	2D02.2	Uvea	1.21E-05	3.37E+00	2.47E+01
Rheumatoid arthritis	FA20	Synovial tissue	2.88E-01	2.25E-01	2.01E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	3.81E-02	-8.20E-02	-5.18E-01
Schizophrenia	6A20	Prefrontal cortex	1.45E-01	5.01E-03	9.65E-03
Schizophrenia	6A20	Superior temporal cortex	1.74E-02	-3.32E-01	-8.91E-01
Scleroderma	4A42.Z	Whole blood	6.10E-01	7.17E-02	1.56E-01
Seizure	8A60-8A6Z	Whole blood	7.56E-01	4.55E-02	6.23E-02
Sensitive skin	EK0Z	Skin	3.51E-01	3.36E-01	1.18E+00
Sepsis with septic shock	1G41	Whole blood	5.72E-45	-1.33E+00	-1.84E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	9.02E-03	-1.17E+00	-2.21E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.69E-01	-8.26E-02	-3.09E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.70E-01	4.32E-02	1.19E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	5.58E-01	-4.18E-02	-4.08E-01
Skin cancer	2C30-2C3Z	Skin	2.83E-04	-5.70E-01	-6.58E-01
Thrombocythemia	3B63	Whole blood	2.25E-04	-2.51E-01	-4.82E-01
Thrombocytopenia	3B64	Whole blood	5.23E-01	1.20E+00	8.88E-01
Thyroid cancer	2D10	Thyroid	1.86E-42	-1.60E+00	-2.64E+00
Tibial muscular dystrophy	8C75	Muscle tissue	6.44E-01	1.19E-01	2.37E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	7.81E-01	-2.59E-01	-6.54E-01
Type 2 diabetes	5A11	Liver tissue	3.45E-01	-1.94E-02	-1.40E-01
Ureter cancer	2C92	Urothelium	7.37E-01	9.61E-03	4.56E-02
Uterine cancer	2C78	Endometrium tissue	9.66E-29	-2.62E+00	-1.60E+00
Vitiligo	ED63.0	Skin	6.76E-01	3.63E-01	8.33E-01