Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE43MW5)

• DME Name: Indoleamine 2,3-dioxygenase 1 (IDO1) DME Info
• Gene Name: IDO1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	8.55E-03	-4.30E-02	-1.43E-01
Alopecia	ED70	Skin from scalp	2.99E-07	3.84E-01	1.01E+00
Alzheimer's disease	8A20	Entorhinal cortex	1.46E-02	-4.58E-02	-2.16E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.22E-01	-8.18E-02	-7.60E-02
Aortic stenosis	BB70	Calcified aortic valve	1.29E-02	5.26E-01	1.06E+00
Apnea	7A40	Hyperplastic tonsil	1.61E-01	3.80E-01	1.04E+00
Arthropathy	FA00-FA5Z	Peripheral blood	1.54E-01	2.06E-01	3.07E-01
Asthma	CA23	Nasal and bronchial airway	8.04E-04	1.35E+00	6.61E-01
Atopic dermatitis	EA80	Skin	1.47E-04	2.04E-01	9.74E-01
Autism	6A02	Whole blood	5.61E-01	-1.17E-01	-1.59E-01
Autoimmune uveitis	9A96	Peripheral monocyte	3.86E-01	8.04E-02	5.05E-01
Autosomal dominant monocytopenia	4B04	Whole blood	1.62E-01	-1.30E+00	-7.87E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.80E-03	2.60E-01	3.87E-01
Batten disease	5C56.1	Whole blood	1.24E-01	-1.67E-01	-1.08E+00
Behcet's disease	4A62	Peripheral blood	8.66E-02	1.98E-01	6.63E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	9.87E-01	-6.29E-02	-3.20E-01
Bladder cancer	2C94	Bladder tissue	5.59E-03	1.28E-01	3.47E-01
Breast cancer	2C60-2C6Z	Breast tissue	1.11E-14	4.23E-01	4.40E-01
Cardioembolic stroke	8B11.20	Whole blood	2.18E-05	-1.03E+00	-1.41E+00
Cervical cancer	2C77	Cervical tissue	4.38E-06	9.08E-01	1.27E+00
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.87E-01	-7.01E-01	-3.71E-01
Chronic hepatitis C	1E51.1	Whole blood	8.23E-01	5.83E-02	3.10E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	9.00E-02	2.22E-01	2.77E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	2.64E-01	-1.10E-01	-7.20E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.14E-01	7.43E-01	3.42E+00
Colon cancer	2B90	Colon tissue	1.29E-17	3.95E-01	5.50E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.56E-01	-4.85E-01	-1.20E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	1.03E-01	-4.14E-01	-1.28E+00
Endometriosis	GA10	Endometrium tissue	1.37E-01	1.88E-01	1.09E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	4.81E-01	-2.33E-02	-7.29E-02
Familial hypercholesterolemia	5C80.00	Whole blood	7.73E-04	-4.98E-01	-1.07E+00
Gastric cancer	2B72	Gastric tissue	4.13E-01	2.56E+00	1.01E+00
Glioblastopma	2A00.00	Nervous tissue	4.82E-39	3.62E-01	9.90E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	8.09E-01	-1.10E-01	-3.73E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.05E-02	2.10E+00	1.16E+00
Head and neck cancer	2D42	Head and neck tissue	2.64E-07	1.75E+00	9.59E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	2.90E-01	-2.80E-02	-8.32E-02
Huntington's disease	8A01.10	Whole blood	5.33E-01	1.05E-01	1.25E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.64E-01	9.74E-01	1.32E+00
Immunodeficiency	4A00-4A20	Peripheral blood	6.52E-02	1.35E-01	1.78E+00
Influenza	1E30	Whole blood	7.17E-01	-4.28E-02	-1.03E-01
Interstitial cystitis	GC00.3	Bladder tissue	2.27E-03	2.28E+00	6.18E+00
Intracranial aneurysm	8B01.0	Intracranial artery	1.31E-02	3.50E-01	9.32E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	9.77E-01	5.80E-02	7.95E-02
Ischemic stroke	8B11	Peripheral blood	6.95E-01	3.17E-02	1.04E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	7.63E-05	-3.63E-01	-2.63E-01
Lateral sclerosis	8B60.4	Skin	1.78E-01	1.02E-01	4.70E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	8.15E-02	1.42E-01	7.53E-01
Liver cancer	2C12.0	Liver tissue	6.99E-08	2.94E-01	8.36E-01
Liver failure	DB99.7-DB99.8	Liver tissue	2.96E-04	5.83E-01	3.69E+00
Lung cancer	2C25	Lung tissue	1.34E-05	-5.52E-01	-4.99E-01
Lupus erythematosus	4A40	Whole blood	3.13E-02	-2.59E-01	-1.62E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	2.11E-01	6.71E-02	3.49E-01
Major depressive disorder	6A70-6A7Z	Whole blood	3.47E-01	1.19E-01	1.80E-01
Melanoma	2C30	Skin	9.53E-07	1.13E+00	1.20E+00
Multiple myeloma	2A83.1	Peripheral blood	7.10E-01	1.33E-02	5.27E-02
Multiple myeloma	2A83.1	Bone marrow	3.79E-01	-1.26E-01	-7.06E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.38E-01	1.92E-01	5.77E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	9.17E-01	-1.04E-03	-3.74E-03
Myelofibrosis	2A20.2	Whole blood	1.97E-03	-6.30E-01	-1.54E+00
Myocardial infarction	BA41-BA50	Peripheral blood	2.43E-01	1.84E-01	2.15E-01
Myopathy	8C70.6	Muscle tissue	8.64E-03	1.05E+00	1.80E+00
Neonatal sepsis	KA60	Whole blood	3.46E-10	-8.57E-01	-1.28E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	5.28E-01	-2.31E-01	-4.60E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	8.20E-02	1.19E-01	5.27E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.53E-01	-1.39E-01	-2.16E-01
Olive pollen allergy	CA08.00	Peripheral blood	2.91E-01	-1.48E+00	-6.87E-01
Oral cancer	2B6E	Oral tissue	3.48E-27	1.50E+00	3.87E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.28E-01	-2.36E-01	-3.70E-01
Osteoporosis	FB83.1	Bone marrow	4.70E-01	3.25E-01	6.93E-01
Ovarian cancer	2C73	Ovarian tissue	3.69E-06	2.12E+00	3.26E+00
Pancreatic cancer	2C10	Pancreas	8.71E-02	3.88E-01	4.27E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	8.21E-01	-2.09E-02	-5.86E-02
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	4.69E-01	-1.90E-03	-7.98E-03
Pituitary cancer	2D12	Pituitary tissue	4.23E-01	2.46E-01	2.10E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	5.24E-01	0.00E+00	0.00E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	7.44E-02	-1.79E-01	-8.10E-01
Polycythemia vera	2A20.4	Whole blood	4.68E-01	-4.52E-02	-1.04E-01
Pompe disease	5C51.3	Biceps muscle	9.24E-01	-3.77E-01	-4.58E-01
Preterm birth	KA21.4Z	Myometrium	7.17E-01	2.99E-01	3.11E-01
Prostate cancer	2C82	Prostate	3.75E-01	-1.71E-01	-2.06E-01
Psoriasis	EA90	Skin	4.83E-31	7.69E-01	1.94E+00
Rectal cancer	2B92	Rectal colon tissue	9.48E-02	3.63E-01	7.85E-01
Renal cancer	2C90-2C91	Kidney	2.30E-14	1.73E+00	5.68E+00
Retinoblastoma	2D02.2	Uvea	5.31E-02	3.92E-01	6.88E-01
Rheumatoid arthritis	FA20	Synovial tissue	9.50E-02	4.06E-01	5.95E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	8.74E-01	-2.03E-01	-2.28E-01
Schizophrenia	6A20	Prefrontal cortex	2.17E-02	1.78E-01	3.56E-01
Schizophrenia	6A20	Superior temporal cortex	5.34E-02	-1.74E-01	-9.30E-01
Scleroderma	4A42.Z	Whole blood	1.87E-02	5.12E-01	1.03E+00
Seizure	8A60-8A6Z	Whole blood	2.44E-01	3.76E-01	2.54E-01
Sensitive skin	EK0Z	Skin	9.18E-01	1.78E-01	2.61E-01
Sepsis with septic shock	1G41	Whole blood	1.32E-09	-5.85E-01	-8.04E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	6.01E-02	3.00E-01	9.95E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.74E-03	5.12E-01	1.71E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	1.39E-01	1.77E-01	3.28E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	3.57E-01	-4.87E-02	-1.75E-01
Skin cancer	2C30-2C3Z	Skin	6.01E-38	9.50E-01	1.82E+00
Thrombocythemia	3B63	Whole blood	1.53E-02	-1.01E-01	-2.40E-01
Thrombocytopenia	3B64	Whole blood	5.74E-01	1.60E-01	4.14E-01
Thyroid cancer	2D10	Thyroid	1.84E-01	-1.02E-01	-7.15E-02
Tibial muscular dystrophy	8C75	Muscle tissue	6.19E-04	-9.41E-01	-1.59E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.70E-02	3.68E-01	1.81E+00
Type 2 diabetes	5A11	Liver tissue	5.84E-01	2.37E-01	7.55E-01
Ureter cancer	2C92	Urothelium	2.08E-01	-1.92E-01	-4.86E-01
Uterine cancer	2C78	Endometrium tissue	4.43E-01	3.09E-01	1.69E-01
Vitiligo	ED63.0	Skin	4.39E-01	-2.40E-02	-3.42E-02