Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE4U39Y)

• DME Name: UDP-glucose pyrophosphorylase (UGPase) DME Info
• Gene Name: UGP2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.00E-21	-7.26E-01	-1.16E+00
Alopecia	ED70	Skin from scalp	3.22E-01	-2.39E-02	-1.21E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.51E-01	6.09E-02	3.03E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	5.38E-01	3.50E-02	1.20E-01
Aortic stenosis	BB70	Calcified aortic valve	6.74E-01	-1.43E-01	-1.53E-01
Apnea	7A40	Hyperplastic tonsil	2.52E-02	8.51E-01	1.79E+00
Arthropathy	FA00-FA5Z	Peripheral blood	9.17E-01	-1.37E-02	-1.45E-01
Asthma	CA23	Nasal and bronchial airway	2.29E-05	1.69E-01	2.41E-01
Atopic dermatitis	EA80	Skin	1.07E-03	-2.72E-01	-1.38E+00
Autism	6A02	Whole blood	1.26E-02	1.75E-01	6.26E-01
Autoimmune uveitis	9A96	Peripheral monocyte	5.16E-01	1.65E-01	6.22E-01
Autosomal dominant monocytopenia	4B04	Whole blood	2.89E-01	-2.96E-02	-7.24E-02
Bacterial infection of gingival	1C1H	Gingival tissue	1.03E-04	-2.06E-01	-6.88E-01
Batten disease	5C56.1	Whole blood	2.11E-01	-2.59E-02	-1.60E-01
Behcet's disease	4A62	Peripheral blood	1.45E-01	-1.15E-01	-4.68E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	8.95E-01	-1.05E-02	-4.79E-02
Bladder cancer	2C94	Bladder tissue	7.32E-02	-2.98E-01	-1.43E+00
Breast cancer	2C60-2C6Z	Breast tissue	1.38E-38	-7.74E-01	-1.15E+00
Cardioembolic stroke	8B11.20	Whole blood	3.90E-05	1.09E-01	1.18E+00
Cervical cancer	2C77	Cervical tissue	2.06E-02	-2.62E-01	-7.30E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	2.32E-01	2.52E-02	1.01E-01
Chronic hepatitis C	1E51.1	Whole blood	9.61E-01	-1.86E-01	-5.34E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	5.64E-02	1.24E-01	5.68E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	9.70E-01	4.95E-02	1.69E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	7.00E-01	1.55E-01	3.83E-01
Colon cancer	2B90	Colon tissue	4.05E-57	-9.63E-01	-2.01E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	2.08E-01	1.31E+00	9.25E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	5.24E-01	1.36E-01	2.11E-01
Endometriosis	GA10	Endometrium tissue	2.56E-02	-7.82E-02	-3.14E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.47E-01	1.02E-01	7.21E-01
Familial hypercholesterolemia	5C80.00	Whole blood	6.28E-03	2.00E-01	7.36E-01
Gastric cancer	2B72	Gastric tissue	9.20E-02	-3.78E-01	-1.30E+00
Glioblastopma	2A00.00	Nervous tissue	4.33E-72	-6.53E-01	-1.60E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	9.95E-01	-9.19E-02	-1.14E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	9.51E-01	-1.63E-01	-4.52E-01
Head and neck cancer	2D42	Head and neck tissue	3.38E-14	-3.16E-01	-9.88E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	4.85E-01	-1.06E-01	-3.45E-01
Huntington's disease	8A01.10	Whole blood	9.38E-01	-4.70E-02	-1.37E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	2.77E-01	-5.80E-02	-1.64E-01
Immunodeficiency	4A00-4A20	Peripheral blood	8.72E-01	-1.65E-03	-2.61E-02
Influenza	1E30	Whole blood	8.91E-01	-2.81E-01	-1.07E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.49E-01	5.45E-02	2.17E-01
Intracranial aneurysm	8B01.0	Intracranial artery	1.12E-01	-3.49E-01	-1.31E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.86E-01	6.37E-02	3.37E-01
Ischemic stroke	8B11	Peripheral blood	7.12E-02	-1.57E-01	-6.12E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.46E-02	1.84E-02	1.29E-01
Lateral sclerosis	8B60.4	Skin	8.50E-01	-6.10E-02	-2.13E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	1.18E-01	-1.75E-01	-4.05E-01
Liver cancer	2C12.0	Liver tissue	2.42E-13	-1.21E+00	-1.62E+00
Liver failure	DB99.7-DB99.8	Liver tissue	1.33E-06	-2.23E+00	-3.82E+00
Lung cancer	2C25	Lung tissue	3.25E-12	2.50E-01	6.91E-01
Lupus erythematosus	4A40	Whole blood	1.81E-03	1.29E-01	3.91E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	7.32E-01	-3.58E-02	-1.60E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.03E-01	-3.34E-02	-2.33E-01
Melanoma	2C30	Skin	4.68E-01	-9.66E-03	-1.65E-02
Multiple myeloma	2A83.1	Peripheral blood	6.74E-01	-1.46E-02	-1.04E-01
Multiple myeloma	2A83.1	Bone marrow	3.43E-05	5.03E-01	2.96E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	5.16E-01	-1.11E-02	-6.23E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	3.43E-01	-9.63E-02	-2.22E-01
Myelofibrosis	2A20.2	Whole blood	4.67E-02	-9.36E-02	-5.47E-01
Myocardial infarction	BA41-BA50	Peripheral blood	1.40E-01	-2.47E-01	-4.80E-01
Myopathy	8C70.6	Muscle tissue	3.83E-01	3.05E-01	6.81E-01
Neonatal sepsis	KA60	Whole blood	9.04E-08	2.98E-01	8.13E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.27E-01	1.54E-01	4.99E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.57E-01	3.18E-01	4.51E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.06E-01	6.49E-01	7.93E-01
Olive pollen allergy	CA08.00	Peripheral blood	3.59E-01	-3.95E-01	-9.02E-01
Oral cancer	2B6E	Oral tissue	4.14E-01	1.90E-01	2.64E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	2.60E-01	-5.30E-01	-5.64E-01
Osteoporosis	FB83.1	Bone marrow	2.42E-01	-1.14E-01	-2.17E+00
Ovarian cancer	2C73	Ovarian tissue	4.72E-02	-3.19E-01	-8.36E-01
Pancreatic cancer	2C10	Pancreas	6.04E-01	1.66E-01	2.80E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	1.49E-01	7.20E-02	2.54E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	7.34E-01	8.54E-02	2.92E-01
Pituitary cancer	2D12	Pituitary tissue	4.94E-04	-1.10E+00	-1.96E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.55E-03	-9.74E-01	-1.99E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	6.23E-01	8.00E-03	5.14E-02
Polycythemia vera	2A20.4	Whole blood	7.33E-07	-1.83E-01	-1.07E+00
Pompe disease	5C51.3	Biceps muscle	7.54E-04	6.35E-01	2.55E+00
Preterm birth	KA21.4Z	Myometrium	9.09E-02	1.92E-01	9.18E-01
Prostate cancer	2C82	Prostate	2.78E-05	-3.92E-01	-1.01E+00
Psoriasis	EA90	Skin	7.10E-03	2.52E-01	5.38E-01
Rectal cancer	2B92	Rectal colon tissue	2.14E-02	-4.14E-01	-1.62E+00
Renal cancer	2C90-2C91	Kidney	2.75E-01	1.64E-02	8.41E-02
Retinoblastoma	2D02.2	Uvea	1.44E-04	5.45E-01	1.94E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.08E-02	-9.60E-01	-1.56E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	3.58E-01	2.45E-02	1.79E-01
Schizophrenia	6A20	Prefrontal cortex	1.83E-01	-5.74E-02	-1.88E-01
Schizophrenia	6A20	Superior temporal cortex	5.12E-02	7.88E-02	4.95E-01
Scleroderma	4A42.Z	Whole blood	2.16E-01	-1.28E-01	-9.22E-01
Seizure	8A60-8A6Z	Whole blood	3.68E-01	1.54E-01	5.67E-01
Sensitive skin	EK0Z	Skin	5.34E-02	-1.52E-01	-1.62E+00
Sepsis with septic shock	1G41	Whole blood	3.18E-13	3.18E-01	9.12E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.87E-01	-4.36E-01	-9.43E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	3.33E-03	-7.99E-01	-1.95E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	5.01E-01	2.71E-01	3.11E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	3.15E-01	3.35E-01	1.24E+00
Skin cancer	2C30-2C3Z	Skin	6.79E-01	3.26E-02	7.29E-02
Thrombocythemia	3B63	Whole blood	5.92E-03	-2.60E-01	-1.50E+00
Thrombocytopenia	3B64	Whole blood	5.89E-01	-4.72E-01	-5.80E-01
Thyroid cancer	2D10	Thyroid	9.30E-03	1.14E-01	3.41E-01
Tibial muscular dystrophy	8C75	Muscle tissue	4.19E-01	1.02E-01	2.16E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.07E-01	-1.06E-01	-3.25E-01
Type 2 diabetes	5A11	Liver tissue	1.36E-01	2.07E-01	6.78E-01
Ureter cancer	2C92	Urothelium	7.02E-01	1.87E-01	5.78E-01
Uterine cancer	2C78	Endometrium tissue	5.62E-07	4.10E-01	7.12E-01
Vitiligo	ED63.0	Skin	6.41E-01	1.78E-02	1.00E-01