Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE6NIY9)

• DME Name: Methionine synthase reductase (MTRR) DME Info
• Gene Name: MTRR

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	5.39E-19	3.95E-01	1.11E+00
Alopecia	ED70	Skin from scalp	2.50E-01	1.88E-02	6.06E-02
Alzheimer's disease	8A20	Entorhinal cortex	1.53E-02	9.36E-02	2.94E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	9.91E-01	-1.84E-01	-7.69E-01
Aortic stenosis	BB70	Calcified aortic valve	7.61E-01	-1.67E-01	-1.92E-01
Apnea	7A40	Hyperplastic tonsil	4.05E-01	5.02E-02	8.34E-02
Arthropathy	FA00-FA5Z	Peripheral blood	1.53E-01	-2.51E-01	-6.98E-01
Asthma	CA23	Nasal and bronchial airway	9.28E-06	9.96E-02	1.86E-01
Atopic dermatitis	EA80	Skin	6.80E-03	-2.74E-01	-1.21E+00
Autism	6A02	Whole blood	9.38E-01	-4.09E-03	-1.33E-02
Autoimmune uveitis	9A96	Peripheral monocyte	4.24E-02	6.04E-02	1.74E-01
Autosomal dominant monocytopenia	4B04	Whole blood	1.54E-03	1.09E+00	2.83E+00
Bacterial infection of gingival	1C1H	Gingival tissue	4.26E-07	2.80E-01	9.49E-01
Batten disease	5C56.1	Whole blood	2.08E-01	-2.36E-01	-1.29E+00
Behcet's disease	4A62	Peripheral blood	8.96E-01	-1.75E-01	-8.17E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	3.26E-01	2.42E-02	1.44E-01
Bladder cancer	2C94	Bladder tissue	1.79E-04	-4.07E-01	-2.47E+00
Breast cancer	2C60-2C6Z	Breast tissue	2.27E-14	1.29E-01	3.40E-01
Cardioembolic stroke	8B11.20	Whole blood	5.91E-01	1.46E-01	4.40E-01
Cervical cancer	2C77	Cervical tissue	2.74E-03	1.50E-01	5.78E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	3.71E-01	-6.69E-02	-5.15E-02
Chronic hepatitis C	1E51.1	Whole blood	6.25E-01	-3.34E-02	-1.04E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	5.82E-01	-5.77E-02	-1.82E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	5.80E-01	1.38E-02	4.74E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.45E-01	-1.53E-01	-7.85E-01
Colon cancer	2B90	Colon tissue	2.29E-10	1.53E-01	5.65E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.18E-01	2.21E-01	2.49E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	2.81E-01	1.28E-01	1.95E-01
Endometriosis	GA10	Endometrium tissue	1.95E-01	2.42E-01	5.23E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.06E-01	8.43E-03	5.76E-02
Familial hypercholesterolemia	5C80.00	Whole blood	1.93E-02	1.91E-01	7.12E-01
Gastric cancer	2B72	Gastric tissue	4.23E-01	4.62E-01	8.89E-01
Glioblastopma	2A00.00	Nervous tissue	1.14E-09	-1.68E-01	-4.30E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	8.11E-01	-1.94E-01	-2.14E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	3.93E-03	4.40E-01	1.57E+00
Head and neck cancer	2D42	Head and neck tissue	9.14E-08	2.30E-01	6.96E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	8.38E-01	-3.36E-02	-1.73E-01
Huntington's disease	8A01.10	Whole blood	4.55E-01	-9.11E-02	-3.46E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	7.22E-03	-4.90E-01	-2.21E+00
Immunodeficiency	4A00-4A20	Peripheral blood	2.31E-01	9.09E-02	5.48E-01
Influenza	1E30	Whole blood	5.24E-04	-1.40E+00	-5.80E+00
Interstitial cystitis	GC00.3	Bladder tissue	3.53E-01	6.01E-02	3.39E-01
Intracranial aneurysm	8B01.0	Intracranial artery	1.73E-02	-4.05E-01	-1.39E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	8.71E-01	4.32E-02	2.18E-01
Ischemic stroke	8B11	Peripheral blood	2.86E-01	-5.80E-03	-2.63E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	5.94E-02	-1.27E-02	-2.75E-02
Lateral sclerosis	8B60.4	Skin	2.97E-01	1.67E-01	5.06E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	1.71E-01	-2.11E-01	-7.74E-01
Liver cancer	2C12.0	Liver tissue	2.22E-01	-5.75E-02	-1.09E-01
Liver failure	DB99.7-DB99.8	Liver tissue	9.80E-07	-1.09E+00	-5.95E+00
Lung cancer	2C25	Lung tissue	9.48E-29	-4.49E-01	-1.45E+00
Lupus erythematosus	4A40	Whole blood	2.13E-01	-3.09E-02	-6.67E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	5.75E-01	-4.45E-03	-2.58E-02
Major depressive disorder	6A70-6A7Z	Whole blood	2.84E-01	-1.05E-02	-2.45E-02
Melanoma	2C30	Skin	8.01E-01	-6.39E-03	-1.40E-02
Multiple myeloma	2A83.1	Peripheral blood	4.23E-01	3.67E-03	2.72E-02
Multiple myeloma	2A83.1	Bone marrow	1.08E-05	9.91E-01	4.04E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	7.36E-01	1.48E-02	5.20E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	1.01E-02	1.46E-01	4.08E-01
Myelofibrosis	2A20.2	Whole blood	9.75E-01	1.13E-01	4.64E-01
Myocardial infarction	BA41-BA50	Peripheral blood	1.09E-02	-3.99E-01	-7.26E-01
Myopathy	8C70.6	Muscle tissue	3.09E-01	-1.40E-01	-5.50E-01
Neonatal sepsis	KA60	Whole blood	5.72E-08	4.59E-01	9.94E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	7.84E-01	2.35E-02	5.53E-02
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.28E-02	5.85E-01	1.97E+00
Obesity related type 2 diabetes	5A11	Omental adipose tissue	4.19E-01	-2.82E-02	-9.18E-02
Olive pollen allergy	CA08.00	Peripheral blood	3.29E-01	-4.51E-01	-9.80E-01
Oral cancer	2B6E	Oral tissue	1.11E-04	5.30E-01	8.80E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	2.04E-01	-1.56E-01	-3.51E-01
Osteoporosis	FB83.1	Bone marrow	1.25E-02	-5.73E-01	-2.39E+00
Ovarian cancer	2C73	Ovarian tissue	5.09E-02	3.28E-01	7.65E-01
Pancreatic cancer	2C10	Pancreas	5.36E-01	-1.44E-01	-3.76E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	3.17E-02	2.76E-01	8.24E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	8.51E-02	1.63E-01	8.88E-01
Pituitary cancer	2D12	Pituitary tissue	3.27E-01	-1.58E-01	-3.59E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	3.00E-01	-1.52E-01	-5.38E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.92E-01	-8.23E-02	-4.12E-01
Polycythemia vera	2A20.4	Whole blood	4.90E-01	5.49E-02	2.18E-01
Pompe disease	5C51.3	Biceps muscle	5.85E-04	-3.61E-01	-2.50E+00
Preterm birth	KA21.4Z	Myometrium	9.13E-01	6.66E-02	1.15E-01
Prostate cancer	2C82	Prostate	4.99E-01	2.43E-01	4.68E-01
Psoriasis	EA90	Skin	1.25E-13	2.56E-01	1.04E+00
Rectal cancer	2B92	Rectal colon tissue	1.54E-02	2.72E-01	1.36E+00
Renal cancer	2C90-2C91	Kidney	6.10E-01	2.22E-01	5.71E-01
Retinoblastoma	2D02.2	Uvea	3.04E-01	1.59E-01	8.03E-01
Rheumatoid arthritis	FA20	Synovial tissue	3.12E-01	-3.21E-01	-4.98E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.17E-01	-5.00E-02	-3.53E-01
Schizophrenia	6A20	Prefrontal cortex	1.88E-01	-1.92E-02	-5.59E-02
Schizophrenia	6A20	Superior temporal cortex	2.92E-01	-3.75E-02	-1.72E-01
Scleroderma	4A42.Z	Whole blood	5.53E-10	-4.79E-01	-4.30E+00
Seizure	8A60-8A6Z	Whole blood	5.80E-01	1.52E-01	4.64E-01
Sensitive skin	EK0Z	Skin	5.86E-02	2.36E-01	1.58E+00
Sepsis with septic shock	1G41	Whole blood	1.55E-02	1.48E-02	4.72E-02
Shwachman-Diamond syndrome	3A70.0	Bone marrow	9.16E-01	4.47E-02	1.30E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	6.59E-02	-1.18E-01	-2.32E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	5.20E-02	-4.05E-01	-2.58E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.59E-01	2.33E-01	9.90E-01
Skin cancer	2C30-2C3Z	Skin	1.56E-04	1.34E-01	4.66E-01
Thrombocythemia	3B63	Whole blood	1.38E-01	2.14E-02	8.01E-02
Thrombocytopenia	3B64	Whole blood	5.94E-01	-6.17E-01	-8.32E-01
Thyroid cancer	2D10	Thyroid	5.15E-01	-2.33E-02	-9.82E-02
Tibial muscular dystrophy	8C75	Muscle tissue	1.05E-04	-6.05E-01	-1.29E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.18E-01	-2.45E-01	-1.06E+00
Type 2 diabetes	5A11	Liver tissue	5.06E-01	3.22E-03	9.53E-03
Ureter cancer	2C92	Urothelium	6.05E-02	1.10E-01	6.37E-01
Uterine cancer	2C78	Endometrium tissue	1.56E-23	4.43E-01	1.02E+00
Vitiligo	ED63.0	Skin	8.42E-03	1.54E-01	1.62E+00