Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE6WXTH)

• DME Name: Phospholipid phosphatase 1 (PLPP1) DME Info
• Gene Name: PLPP1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	6.16E-12	2.20E-01	5.69E-01
Alopecia	ED70	Skin from scalp	4.54E-01	2.60E-02	1.12E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.44E-08	2.96E-01	9.54E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	7.07E-01	5.19E-02	1.72E-01
Aortic stenosis	BB70	Calcified aortic valve	8.23E-01	3.87E-01	3.79E-01
Apnea	7A40	Hyperplastic tonsil	1.47E-01	-5.82E-01	-1.73E+00
Arthropathy	FA00-FA5Z	Peripheral blood	1.01E-01	-3.07E-01	-1.17E+00
Asthma	CA23	Nasal and bronchial airway	1.10E-05	1.09E+00	1.26E+00
Atopic dermatitis	EA80	Skin	3.01E-06	-4.01E-01	-2.28E+00
Autism	6A02	Whole blood	7.95E-01	-9.27E-02	-2.94E-01
Autoimmune uveitis	9A96	Peripheral monocyte	3.35E-01	9.30E-02	4.81E-01
Autosomal dominant monocytopenia	4B04	Whole blood	4.13E-02	3.20E-01	1.41E+00
Bacterial infection of gingival	1C1H	Gingival tissue	3.38E-05	3.27E-01	8.78E-01
Batten disease	5C56.1	Whole blood	8.87E-01	1.01E-01	5.09E-01
Behcet's disease	4A62	Peripheral blood	1.61E-01	-9.37E-02	-4.08E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	7.97E-01	3.81E-02	2.00E-01
Bladder cancer	2C94	Bladder tissue	1.13E-12	-1.36E+00	-6.23E+00
Breast cancer	2C60-2C6Z	Breast tissue	1.89E-140	-1.59E+00	-2.63E+00
Cardioembolic stroke	8B11.20	Whole blood	1.11E-01	-1.56E-01	-6.06E-01
Cervical cancer	2C77	Cervical tissue	1.63E-01	-9.11E-02	-2.16E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	8.43E-01	-1.10E-01	-1.80E-01
Chronic hepatitis C	1E51.1	Whole blood	7.97E-01	1.45E-01	8.03E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	8.56E-01	-5.19E-02	-1.68E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.18E-01	-1.21E-01	-3.78E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.15E-01	-3.05E-01	-7.69E-01
Colon cancer	2B90	Colon tissue	4.87E-135	-1.64E+00	-4.29E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	4.38E-01	-1.75E-01	-5.48E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	6.95E-01	-1.37E-01	-4.81E-01
Endometriosis	GA10	Endometrium tissue	2.93E-01	-1.40E-02	-2.39E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	4.36E-03	2.42E-01	1.27E+00
Familial hypercholesterolemia	5C80.00	Whole blood	1.96E-03	-2.25E-01	-8.06E-01
Gastric cancer	2B72	Gastric tissue	3.80E-01	-7.03E-02	-7.55E-02
Glioblastopma	2A00.00	Nervous tissue	5.12E-01	9.16E-02	2.18E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	5.34E-01	2.59E-02	1.39E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	7.92E-04	-4.04E-01	-1.16E+00
Head and neck cancer	2D42	Head and neck tissue	8.12E-08	3.31E-01	3.91E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.56E-01	1.16E-01	3.28E-01
Huntington's disease	8A01.10	Whole blood	2.26E-01	-1.12E-01	-5.73E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	7.83E-01	-2.42E-01	-8.65E-01
Immunodeficiency	4A00-4A20	Peripheral blood	7.16E-02	2.14E-01	7.99E-01
Influenza	1E30	Whole blood	2.91E-04	-7.08E-01	-8.14E+00
Interstitial cystitis	GC00.3	Bladder tissue	9.07E-01	8.56E-02	5.78E-01
Intracranial aneurysm	8B01.0	Intracranial artery	1.70E-01	-1.70E-01	-4.80E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.17E-02	-6.86E-02	-5.02E-01
Ischemic stroke	8B11	Peripheral blood	3.69E-01	9.63E-05	3.04E-04
Juvenile idiopathic arthritis	FA24	Peripheral blood	9.80E-01	1.84E-01	5.37E-01
Lateral sclerosis	8B60.4	Skin	1.84E-01	4.54E-01	1.24E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	9.80E-02	-1.11E-01	-1.37E-01
Liver cancer	2C12.0	Liver tissue	5.87E-04	3.95E-01	8.30E-01
Liver failure	DB99.7-DB99.8	Liver tissue	4.39E-05	-7.43E-01	-3.27E+00
Lung cancer	2C25	Lung tissue	3.12E-42	-5.87E-01	-1.66E+00
Lupus erythematosus	4A40	Whole blood	5.54E-01	1.11E-01	2.01E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	5.85E-01	2.54E-02	1.34E-01
Major depressive disorder	6A70-6A7Z	Whole blood	3.35E-02	-6.59E-02	-1.99E-01
Melanoma	2C30	Skin	9.83E-05	-5.49E-01	-1.04E+00
Multiple myeloma	2A83.1	Peripheral blood	6.08E-01	2.88E-01	4.63E-01
Multiple myeloma	2A83.1	Bone marrow	4.23E-08	1.06E+00	5.89E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.26E-01	-9.22E-02	-2.63E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	8.29E-06	2.66E-01	1.14E+00
Myelofibrosis	2A20.2	Whole blood	3.68E-03	-3.11E-01	-2.21E+00
Myocardial infarction	BA41-BA50	Peripheral blood	1.41E-01	-4.14E-01	-5.05E-01
Myopathy	8C70.6	Muscle tissue	6.70E-03	3.04E-01	1.36E+00
Neonatal sepsis	KA60	Whole blood	3.93E-17	-5.89E-01	-1.45E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.47E-08	-1.11E+00	-3.44E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	9.53E-01	1.54E-01	4.88E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.74E-01	1.46E-01	5.13E-01
Olive pollen allergy	CA08.00	Peripheral blood	3.75E-01	-1.01E-01	-2.31E-01
Oral cancer	2B6E	Oral tissue	8.79E-01	-1.69E-01	-2.59E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	2.19E-01	4.20E-01	5.88E-01
Osteoporosis	FB83.1	Bone marrow	4.61E-01	-6.98E-02	-1.25E-01
Ovarian cancer	2C73	Ovarian tissue	7.40E-01	1.65E-01	2.62E-01
Pancreatic cancer	2C10	Pancreas	8.40E-01	2.72E-03	5.30E-03
Parkinson's disease	8A00.0	Substantia nigra tissue	6.39E-01	-4.01E-02	-1.36E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.23E-01	-5.21E-02	-3.24E-01
Pituitary cancer	2D12	Pituitary tissue	1.40E-04	8.67E-01	1.65E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.04E-02	5.68E-01	9.82E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	1.54E-01	2.36E-01	9.45E-01
Polycythemia vera	2A20.4	Whole blood	7.77E-11	-2.67E-01	-1.96E+00
Pompe disease	5C51.3	Biceps muscle	2.50E-05	7.88E-01	4.62E+00
Preterm birth	KA21.4Z	Myometrium	1.74E-01	5.71E-01	7.00E-01
Prostate cancer	2C82	Prostate	2.03E-02	-3.16E-01	-6.16E-01
Psoriasis	EA90	Skin	3.20E-20	-5.29E-01	-1.26E+00
Rectal cancer	2B92	Rectal colon tissue	4.32E-23	-1.35E+00	-1.37E+01
Renal cancer	2C90-2C91	Kidney	2.58E-01	1.77E-01	4.76E-01
Retinoblastoma	2D02.2	Uvea	6.58E-02	5.37E-01	2.53E+00
Rheumatoid arthritis	FA20	Synovial tissue	5.97E-05	8.90E-01	2.95E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	9.89E-03	-1.29E-01	-6.21E-01
Schizophrenia	6A20	Prefrontal cortex	1.20E-01	-1.10E-01	-1.17E-01
Schizophrenia	6A20	Superior temporal cortex	1.08E-01	-1.01E-01	-4.45E-01
Scleroderma	4A42.Z	Whole blood	2.28E-03	-2.75E-01	-1.44E+00
Seizure	8A60-8A6Z	Whole blood	8.45E-01	5.86E-02	1.38E-01
Sensitive skin	EK0Z	Skin	6.81E-02	-1.18E-01	-7.76E-01
Sepsis with septic shock	1G41	Whole blood	7.24E-28	-4.75E-01	-1.17E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.53E-02	-2.61E-01	-1.60E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	2.16E-02	-4.22E-01	-1.25E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	5.58E-01	-9.75E-01	-1.17E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	8.28E-01	1.07E-01	4.81E-01
Skin cancer	2C30-2C3Z	Skin	6.49E-70	-9.60E-01	-2.02E+00
Thrombocythemia	3B63	Whole blood	1.82E-04	-2.35E-01	-1.79E+00
Thrombocytopenia	3B64	Whole blood	7.94E-01	4.00E-02	7.88E-02
Thyroid cancer	2D10	Thyroid	1.06E-09	4.25E-01	1.07E+00
Tibial muscular dystrophy	8C75	Muscle tissue	2.24E-04	4.28E-01	1.19E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.03E-01	5.47E-01	2.27E+00
Type 2 diabetes	5A11	Liver tissue	9.05E-01	-1.49E-01	-2.81E-01
Ureter cancer	2C92	Urothelium	8.35E-01	5.48E-02	1.25E-01
Uterine cancer	2C78	Endometrium tissue	7.77E-50	-1.99E+00	-2.47E+00
Vitiligo	ED63.0	Skin	1.03E-01	-2.14E-01	-8.57E-01