Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE708H2)

• DME Name: Nitric oxide synthase endothelial (NOS3) DME Info
• Gene Name: NOS3

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	3.26E-02	9.15E-02	3.42E-01
Alopecia	ED70	Skin from scalp	1.03E-02	-1.71E-01	-6.61E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.19E-01	7.75E-02	1.53E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	9.49E-01	-1.49E-02	-1.11E-01
Aortic stenosis	BB70	Calcified aortic valve	8.31E-01	1.68E-02	2.73E-02
Apnea	7A40	Hyperplastic tonsil	1.14E-02	-3.57E-01	-1.96E+00
Arthropathy	FA00-FA5Z	Peripheral blood	9.56E-01	8.19E-03	4.15E-02
Asthma	CA23	Nasal and bronchial airway	1.02E-01	-9.97E-02	-2.12E-01
Atopic dermatitis	EA80	Skin	1.45E-04	4.08E-01	1.07E+00
Autism	6A02	Whole blood	9.78E-01	-2.57E-02	-1.12E-01
Autoimmune uveitis	9A96	Peripheral monocyte	1.61E-01	-2.19E-01	-1.15E+00
Autosomal dominant monocytopenia	4B04	Whole blood	3.87E-01	-1.13E-01	-6.17E-01
Bacterial infection of gingival	1C1H	Gingival tissue	3.39E-13	5.84E-01	1.48E+00
Batten disease	5C56.1	Whole blood	4.60E-02	-2.14E-01	-9.07E-01
Behcet's disease	4A62	Peripheral blood	3.05E-01	-6.42E-02	-1.67E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	8.52E-01	1.21E-01	4.39E-01
Bladder cancer	2C94	Bladder tissue	9.83E-01	1.40E-01	2.73E-01
Breast cancer	2C60-2C6Z	Breast tissue	4.60E-01	-2.92E-02	-5.12E-02
Cardioembolic stroke	8B11.20	Whole blood	8.47E-02	-2.34E-02	-9.86E-02
Cervical cancer	2C77	Cervical tissue	3.11E-02	1.07E-01	5.36E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.59E-01	6.54E-02	3.15E-01
Chronic hepatitis C	1E51.1	Whole blood	1.88E-01	-1.92E-01	-7.62E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.47E-01	-1.82E-01	-3.39E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	4.85E-05	2.63E-01	5.77E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.59E-01	-1.27E-01	-6.81E-01
Colon cancer	2B90	Colon tissue	1.99E-64	6.41E-01	1.72E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.68E-01	-1.11E-01	-8.52E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	7.60E-01	2.06E-02	5.81E-02
Endometriosis	GA10	Endometrium tissue	2.51E-06	4.50E-01	1.94E+00
Familial hypercholesterolemia	5C80.00	Peripheral blood	9.41E-02	2.97E-02	1.58E-01
Familial hypercholesterolemia	5C80.00	Whole blood	7.00E-02	-1.16E-01	-4.35E-01
Gastric cancer	2B72	Gastric tissue	7.45E-02	7.24E-01	2.19E+00
Glioblastopma	2A00.00	Nervous tissue	4.05E-29	-4.17E-01	-7.15E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	3.48E-01	-3.29E-01	-1.13E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	5.42E-02	-2.55E-01	-3.82E-01
Head and neck cancer	2D42	Head and neck tissue	1.23E-05	1.56E-01	6.00E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	5.10E-01	2.01E-02	7.55E-02
Huntington's disease	8A01.10	Whole blood	5.78E-01	8.10E-02	4.69E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	4.69E-01	-8.51E-02	-1.13E-01
Immunodeficiency	4A00-4A20	Peripheral blood	4.82E-01	4.31E-02	1.82E-01
Influenza	1E30	Whole blood	1.58E-01	2.65E-01	2.10E+00
Interstitial cystitis	GC00.3	Bladder tissue	9.84E-03	9.62E-01	1.99E+00
Intracranial aneurysm	8B01.0	Intracranial artery	9.37E-01	0.00E+00	0.00E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.42E-01	-4.37E-02	-1.91E-01
Ischemic stroke	8B11	Peripheral blood	4.87E-01	3.53E-02	2.16E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.60E-02	-3.27E-02	-1.17E-01
Lateral sclerosis	8B60.4	Skin	2.67E-01	-2.65E-01	-4.21E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	1.94E-01	-1.12E-01	-6.74E-01
Liver cancer	2C12.0	Liver tissue	2.00E-01	-1.81E-01	-4.11E-01
Liver failure	DB99.7-DB99.8	Liver tissue	8.93E-01	3.19E-02	1.87E-01
Lung cancer	2C25	Lung tissue	1.51E-09	-4.67E-01	-8.58E-01
Lupus erythematosus	4A40	Whole blood	1.43E-01	-2.40E-02	-7.76E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	5.48E-01	6.42E-02	2.40E-01
Major depressive disorder	6A70-6A7Z	Whole blood	8.09E-01	-1.98E-02	-7.83E-02
Melanoma	2C30	Skin	6.28E-01	3.69E-02	5.55E-02
Multiple myeloma	2A83.1	Peripheral blood	4.86E-01	-4.34E-02	-1.16E-01
Multiple myeloma	2A83.1	Bone marrow	2.18E-01	-2.21E-01	-6.85E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	5.21E-01	2.79E-02	1.34E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.64E-02	3.86E-02	2.16E-01
Myelofibrosis	2A20.2	Whole blood	6.79E-01	1.25E-02	8.53E-02
Myocardial infarction	BA41-BA50	Peripheral blood	5.55E-01	-1.55E-02	-4.28E-02
Myopathy	8C70.6	Muscle tissue	2.63E-01	-1.81E-01	-9.12E-01
Neonatal sepsis	KA60	Whole blood	1.26E-04	-1.63E-01	-5.98E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	9.10E-01	-9.76E-02	-2.31E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	6.95E-01	7.04E-02	2.24E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	7.79E-01	-1.94E-02	-7.01E-02
Olive pollen allergy	CA08.00	Peripheral blood	4.33E-01	3.80E-02	1.69E-01
Oral cancer	2B6E	Oral tissue	8.12E-01	-5.95E-02	-1.59E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	7.07E-01	-5.87E-02	-2.53E-01
Osteoporosis	FB83.1	Bone marrow	4.06E-01	1.20E-02	7.12E-02
Ovarian cancer	2C73	Ovarian tissue	3.06E-02	2.05E-01	5.04E-01
Pancreatic cancer	2C10	Pancreas	5.10E-01	1.68E-01	2.68E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	4.65E-01	3.69E-01	7.34E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.78E-01	-1.73E-02	-7.78E-02
Pituitary cancer	2D12	Pituitary tissue	1.32E-01	-3.58E-01	-7.14E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	8.98E-03	-5.20E-01	-1.05E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	1.45E-01	2.89E-01	9.69E-01
Polycythemia vera	2A20.4	Whole blood	1.05E-03	-8.63E-02	-6.13E-01
Pompe disease	5C51.3	Biceps muscle	9.72E-01	5.86E-02	2.81E-01
Preterm birth	KA21.4Z	Myometrium	1.61E-01	-4.87E-01	-9.39E-01
Prostate cancer	2C82	Prostate	1.20E-02	6.62E-01	9.63E-01
Psoriasis	EA90	Skin	1.97E-07	2.36E-01	6.12E-01
Rectal cancer	2B92	Rectal colon tissue	8.77E-04	7.99E-01	2.40E+00
Renal cancer	2C90-2C91	Kidney	8.99E-01	-1.02E-01	-3.54E-01
Retinoblastoma	2D02.2	Uvea	5.36E-02	2.70E-01	1.03E+00
Rheumatoid arthritis	FA20	Synovial tissue	6.80E-05	5.88E-01	2.58E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	4.45E-01	1.02E-02	4.73E-02
Schizophrenia	6A20	Prefrontal cortex	1.88E-01	3.79E-02	1.34E-01
Schizophrenia	6A20	Superior temporal cortex	3.02E-01	1.07E-01	4.47E-01
Scleroderma	4A42.Z	Whole blood	1.73E-03	3.08E-01	1.62E+00
Seizure	8A60-8A6Z	Whole blood	6.49E-01	-3.74E-02	-1.62E-01
Sensitive skin	EK0Z	Skin	9.13E-01	-2.15E-02	-9.62E-02
Sepsis with septic shock	1G41	Whole blood	3.03E-04	-7.00E-02	-2.21E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.25E-01	-9.65E-02	-6.24E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	8.73E-01	8.71E-02	4.15E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	8.71E-01	-9.19E-02	-1.20E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.25E-01	-1.74E-01	-2.10E+00
Skin cancer	2C30-2C3Z	Skin	1.49E-06	1.52E-01	3.54E-01
Thrombocythemia	3B63	Whole blood	4.71E-02	-1.47E-01	-1.08E+00
Thrombocytopenia	3B64	Whole blood	6.54E-01	6.36E-01	5.93E-01
Thyroid cancer	2D10	Thyroid	1.84E-15	3.29E-01	1.01E+00
Tibial muscular dystrophy	8C75	Muscle tissue	5.52E-01	-9.39E-02	-1.75E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.61E-01	-7.75E-02	-1.46E+00
Type 2 diabetes	5A11	Liver tissue	4.41E-01	-1.35E-01	-5.44E-01
Ureter cancer	2C92	Urothelium	6.19E-01	6.83E-04	2.09E-03
Uterine cancer	2C78	Endometrium tissue	7.96E-06	-2.99E-01	-4.28E-01
Vitiligo	ED63.0	Skin	6.75E-02	-1.58E-01	-1.06E+00