Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE7G63U)

• DME Name: Mevalonate pyrophosphate decarboxylase (MPD) DME Info
• Gene Name: MVD

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	7.10E-04	2.01E-01	5.89E-01
Alopecia	ED70	Skin from scalp	9.34E-01	1.03E-01	1.45E-01
Alzheimer's disease	8A20	Entorhinal cortex	7.51E-06	-1.19E-01	-5.57E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.14E-01	7.99E-02	3.02E-01
Aortic stenosis	BB70	Calcified aortic valve	3.18E-01	1.68E-01	3.64E-01
Apnea	7A40	Hyperplastic tonsil	1.47E-01	-2.46E-01	-8.85E-01
Arthropathy	FA00-FA5Z	Peripheral blood	6.05E-01	-6.21E-02	-4.17E-01
Asthma	CA23	Nasal and bronchial airway	7.84E-02	8.06E-02	2.04E-01
Atopic dermatitis	EA80	Skin	2.33E-01	5.43E-02	7.82E-02
Autism	6A02	Whole blood	2.49E-03	-2.89E-01	-9.64E-01
Autoimmune uveitis	9A96	Peripheral monocyte	8.49E-02	-2.78E-01	-2.48E+00
Autosomal dominant monocytopenia	4B04	Whole blood	1.82E-01	2.94E-02	2.21E-01
Bacterial infection of gingival	1C1H	Gingival tissue	7.11E-01	2.78E-02	8.62E-02
Batten disease	5C56.1	Whole blood	4.36E-01	4.25E-02	3.26E-01
Behcet's disease	4A62	Peripheral blood	5.87E-01	-4.82E-03	-2.66E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	8.89E-02	-7.93E-02	-3.91E-01
Bladder cancer	2C94	Bladder tissue	2.89E-01	1.58E-01	6.95E-01
Breast cancer	2C60-2C6Z	Breast tissue	1.88E-05	1.48E-01	3.17E-01
Cardioembolic stroke	8B11.20	Whole blood	3.43E-06	-2.53E-01	-1.31E+00
Cervical cancer	2C77	Cervical tissue	7.15E-01	-4.57E-02	-1.27E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	3.22E-02	1.96E-01	7.99E-01
Chronic hepatitis C	1E51.1	Whole blood	9.83E-01	-1.37E-02	-5.29E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	3.00E-01	-7.27E-02	-1.86E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.81E-02	2.36E-01	5.75E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	6.06E-01	-1.05E-01	-3.98E-01
Colon cancer	2B90	Colon tissue	1.30E-06	-1.69E-01	-4.63E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	2.45E-01	-4.59E-01	-6.69E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	5.42E-01	-2.30E-01	-7.70E-01
Endometriosis	GA10	Endometrium tissue	5.47E-01	2.97E-02	4.28E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	4.34E-01	2.82E-03	1.09E-02
Familial hypercholesterolemia	5C80.00	Whole blood	7.47E-01	-6.21E-02	-1.64E-01
Gastric cancer	2B72	Gastric tissue	3.98E-01	-2.48E-01	-5.60E-01
Glioblastopma	2A00.00	Nervous tissue	7.10E-104	-5.94E-01	-1.63E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	8.65E-01	-9.24E-02	-1.90E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	7.36E-03	-3.86E-01	-1.42E+00
Head and neck cancer	2D42	Head and neck tissue	4.87E-01	8.81E-02	2.17E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	4.60E-01	-5.61E-02	-2.80E-01
Huntington's disease	8A01.10	Whole blood	3.96E-01	0.00E+00	0.00E+00
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.26E-01	-4.16E-01	-1.05E+00
Immunodeficiency	4A00-4A20	Peripheral blood	9.50E-01	5.10E-02	3.82E-01
Influenza	1E30	Whole blood	1.87E-02	-4.70E-01	-1.88E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.75E-01	3.13E-01	1.35E+00
Intracranial aneurysm	8B01.0	Intracranial artery	7.65E-01	1.61E-01	3.71E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.28E-01	-6.68E-02	-2.15E-01
Ischemic stroke	8B11	Peripheral blood	2.35E-01	-4.55E-02	-2.81E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.67E-01	-4.78E-02	-1.46E-01
Lateral sclerosis	8B60.4	Skin	5.83E-01	-3.84E-02	-1.50E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	3.43E-01	-2.53E-01	-8.41E-01
Liver cancer	2C12.0	Liver tissue	2.56E-02	-1.25E-01	-3.10E-01
Liver failure	DB99.7-DB99.8	Liver tissue	2.66E-02	-4.17E-01	-8.33E-01
Lung cancer	2C25	Lung tissue	1.36E-15	-2.28E-01	-7.10E-01
Lupus erythematosus	4A40	Whole blood	1.97E-03	-1.95E-01	-5.77E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	1.32E-01	-7.41E-02	-3.99E-01
Major depressive disorder	6A70-6A7Z	Whole blood	6.78E-02	4.36E-02	2.16E-01
Melanoma	2C30	Skin	7.90E-06	-1.02E+00	-1.14E+00
Multiple myeloma	2A83.1	Peripheral blood	3.38E-01	9.39E-02	4.79E-01
Multiple myeloma	2A83.1	Bone marrow	8.67E-01	1.42E-01	3.79E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	9.51E-03	2.07E-01	9.15E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	4.77E-02	-8.64E-02	-3.77E-01
Myelofibrosis	2A20.2	Whole blood	2.35E-02	1.55E-01	7.17E-01
Myocardial infarction	BA41-BA50	Peripheral blood	1.42E-01	1.27E-01	4.09E-01
Myopathy	8C70.6	Muscle tissue	8.54E-02	-8.76E-02	-5.53E-01
Neonatal sepsis	KA60	Whole blood	4.62E-01	5.66E-02	1.57E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.71E-06	-7.84E-01	-3.22E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.85E-01	-1.58E-01	-5.59E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.91E-01	3.75E-03	2.10E-02
Olive pollen allergy	CA08.00	Peripheral blood	6.34E-02	1.64E-01	9.98E-01
Oral cancer	2B6E	Oral tissue	6.35E-05	-4.44E-01	-9.85E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	1.06E-01	-4.14E-01	-1.33E+00
Osteoporosis	FB83.1	Bone marrow	3.04E-01	1.68E-01	9.09E-01
Ovarian cancer	2C73	Ovarian tissue	4.04E-01	-3.12E-02	-5.73E-02
Pancreatic cancer	2C10	Pancreas	4.39E-01	1.68E-03	3.57E-03
Parkinson's disease	8A00.0	Substantia nigra tissue	3.69E-01	-1.72E-01	-5.56E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.00E-01	6.94E-02	3.05E-01
Pituitary cancer	2D12	Pituitary tissue	6.16E-03	2.48E-01	1.21E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	8.49E-01	-5.32E-02	-2.13E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	8.29E-01	-5.05E-02	-1.61E-01
Polycythemia vera	2A20.4	Whole blood	9.57E-04	9.42E-02	4.12E-01
Pompe disease	5C51.3	Biceps muscle	7.75E-03	-3.45E-01	-1.48E+00
Preterm birth	KA21.4Z	Myometrium	3.25E-01	5.66E-02	1.67E-01
Prostate cancer	2C82	Prostate	3.72E-02	-3.14E-01	-4.80E-01
Psoriasis	EA90	Skin	1.33E-03	-2.96E-01	-5.07E-01
Rectal cancer	2B92	Rectal colon tissue	5.92E-02	-3.12E-01	-1.45E+00
Renal cancer	2C90-2C91	Kidney	1.93E-08	-3.79E-01	-3.53E+00
Retinoblastoma	2D02.2	Uvea	1.17E-05	-5.71E-01	-2.47E+00
Rheumatoid arthritis	FA20	Synovial tissue	3.39E-01	-3.90E-01	-9.94E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	8.94E-01	2.61E-02	1.57E-01
Schizophrenia	6A20	Prefrontal cortex	3.87E-01	-1.90E-02	-7.51E-02
Schizophrenia	6A20	Superior temporal cortex	6.97E-01	3.29E-02	2.33E-01
Scleroderma	4A42.Z	Whole blood	5.16E-01	9.00E-02	7.54E-01
Seizure	8A60-8A6Z	Whole blood	5.77E-01	-1.01E-01	-3.35E-01
Sensitive skin	EK0Z	Skin	5.70E-01	-3.20E-02	-8.73E-02
Sepsis with septic shock	1G41	Whole blood	2.51E-03	-1.77E-01	-4.72E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	9.26E-01	1.71E-01	1.07E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.90E-01	1.81E-01	3.55E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.55E-01	-1.04E-02	-2.29E-02
Sjogren's syndrome	4A43.2	Salivary gland tissue	7.61E-01	-7.06E-02	-4.36E-01
Skin cancer	2C30-2C3Z	Skin	7.41E-40	-7.39E-01	-1.16E+00
Thrombocythemia	3B63	Whole blood	7.00E-01	-4.48E-02	-2.13E-01
Thrombocytopenia	3B64	Whole blood	4.36E-01	6.04E-01	5.86E-01
Thyroid cancer	2D10	Thyroid	4.93E-06	-2.22E-01	-8.61E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.14E-02	-2.16E-01	-6.58E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.40E-02	-2.98E-01	-6.12E+00
Type 2 diabetes	5A11	Liver tissue	9.62E-01	-1.95E-02	-5.17E-02
Ureter cancer	2C92	Urothelium	6.19E-01	-7.24E-02	-1.77E-01
Uterine cancer	2C78	Endometrium tissue	4.08E-02	-6.52E-02	-1.62E-01
Vitiligo	ED63.0	Skin	8.37E-01	-6.96E-02	-1.11E-01