Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE9JFMC)

• DME Name: NADPH-dependent carbonyl reductase 1 (CBR1) DME Info
• Gene Name: CBR1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.53E-01	6.86E-03	1.09E-02
Alopecia	ED70	Skin from scalp	5.14E-02	-4.86E-02	-1.37E-01
Alzheimer's disease	8A20	Entorhinal cortex	3.47E-01	1.55E-01	2.60E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.85E-01	3.68E-01	8.18E-01
Aortic stenosis	BB70	Calcified aortic valve	7.04E-01	-1.16E-01	-1.14E-01
Apnea	7A40	Hyperplastic tonsil	4.77E-02	-1.29E+00	-1.82E+00
Arthropathy	FA00-FA5Z	Peripheral blood	9.87E-01	-6.71E-03	-3.03E-02
Asthma	CA23	Nasal and bronchial airway	1.94E-06	7.14E-01	7.66E-01
Atopic dermatitis	EA80	Skin	1.86E-01	-3.86E-02	-2.58E-01
Autism	6A02	Whole blood	4.99E-01	6.46E-02	2.31E-01
Autoimmune uveitis	9A96	Peripheral monocyte	4.00E-01	-3.40E-01	-1.22E+00
Autosomal dominant monocytopenia	4B04	Whole blood	3.34E-01	1.62E-01	3.75E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.50E-04	-2.10E-01	-5.63E-01
Batten disease	5C56.1	Whole blood	1.50E-01	-6.15E-02	-5.81E-01
Behcet's disease	4A62	Peripheral blood	1.07E-01	9.55E-02	3.13E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	8.81E-01	-8.53E-02	-2.39E-01
Bladder cancer	2C94	Bladder tissue	6.99E-08	-6.34E-01	-3.82E+00
Breast cancer	2C60-2C6Z	Breast tissue	3.16E-03	2.61E-01	4.89E-01
Cardioembolic stroke	8B11.20	Whole blood	6.63E-09	-4.99E-01	-2.00E+00
Cervical cancer	2C77	Cervical tissue	5.26E-01	-2.88E-01	-5.95E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	4.70E-01	-4.30E-02	-4.84E-02
Chronic hepatitis C	1E51.1	Whole blood	4.10E-01	-2.52E-01	-7.73E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	9.91E-01	-6.27E-05	-1.20E-04
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	8.30E-04	4.99E-01	5.47E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.29E-02	-7.23E-01	-1.44E+00
Colon cancer	2B90	Colon tissue	2.98E-20	-4.47E-01	-7.79E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	7.80E-01	7.59E-02	2.92E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	7.63E-01	3.96E-02	6.17E-02
Endometriosis	GA10	Endometrium tissue	6.76E-01	-2.71E-02	-3.51E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	4.18E-01	2.50E-02	1.35E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.53E-10	1.09E+00	2.10E+00
Gastric cancer	2B72	Gastric tissue	3.81E-01	-1.16E+00	-1.06E+00
Glioblastopma	2A00.00	Nervous tissue	2.90E-30	-4.67E-01	-6.56E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	2.32E-01	-1.30E+00	-1.59E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	4.21E-02	-5.69E-01	-8.18E-01
Head and neck cancer	2D42	Head and neck tissue	9.32E-01	-8.81E-02	-1.20E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	6.20E-01	2.62E-01	2.78E-01
Huntington's disease	8A01.10	Whole blood	8.10E-01	-5.16E-02	-1.69E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	5.02E-01	-3.21E-02	-9.35E-02
Immunodeficiency	4A00-4A20	Peripheral blood	3.86E-01	1.46E-01	6.36E-01
Influenza	1E30	Whole blood	2.00E-01	4.39E-01	1.26E+00
Interstitial cystitis	GC00.3	Bladder tissue	5.80E-01	-7.88E-02	-5.69E-01
Intracranial aneurysm	8B01.0	Intracranial artery	2.85E-01	1.37E-01	4.45E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	5.62E-01	-7.40E-02	-1.22E-01
Ischemic stroke	8B11	Peripheral blood	4.64E-02	-1.88E-01	-4.91E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.25E-12	-5.21E-01	-1.18E+00
Lateral sclerosis	8B60.4	Skin	1.26E-01	3.72E-01	1.09E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	4.31E-02	-3.84E-01	-8.37E-01
Liver cancer	2C12.0	Liver tissue	3.72E-01	-2.64E-01	-3.01E-01
Liver failure	DB99.7-DB99.8	Liver tissue	9.52E-01	5.56E-02	1.54E-01
Lung cancer	2C25	Lung tissue	2.14E-28	1.57E-01	4.17E-01
Lupus erythematosus	4A40	Whole blood	4.60E-04	2.84E-01	4.52E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	8.59E-01	-2.73E-03	-7.74E-03
Major depressive disorder	6A70-6A7Z	Whole blood	6.88E-01	-6.37E-03	-1.42E-02
Melanoma	2C30	Skin	5.99E-01	-7.08E-02	-1.30E-01
Multiple myeloma	2A83.1	Peripheral blood	3.94E-01	-7.51E-01	-6.73E-01
Multiple myeloma	2A83.1	Bone marrow	1.43E-05	8.36E-01	3.46E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	8.86E-01	-7.04E-02	-2.77E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	6.03E-03	1.44E-01	2.59E-01
Myelofibrosis	2A20.2	Whole blood	1.99E-01	-1.15E-01	-6.10E-01
Myocardial infarction	BA41-BA50	Peripheral blood	2.44E-03	-2.83E-01	-6.29E-01
Myopathy	8C70.6	Muscle tissue	1.56E-06	8.05E-01	3.72E+00
Neonatal sepsis	KA60	Whole blood	3.31E-03	7.61E-02	2.47E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.92E-05	-1.16E+00	-2.15E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.61E-02	-4.93E-01	-1.20E+00
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.12E-02	-3.90E-01	-1.74E+00
Olive pollen allergy	CA08.00	Peripheral blood	2.45E-01	-2.95E-01	-4.47E-01
Oral cancer	2B6E	Oral tissue	1.48E-05	-6.05E-01	-7.35E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	3.26E-01	4.91E-01	5.32E-01
Osteoporosis	FB83.1	Bone marrow	3.58E-03	-3.94E-01	-2.75E+00
Ovarian cancer	2C73	Ovarian tissue	4.64E-02	5.25E-01	1.08E+00
Pancreatic cancer	2C10	Pancreas	2.09E-09	9.33E-01	2.73E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	1.40E-01	5.11E-01	9.58E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.15E-04	5.32E-01	1.37E+00
Pituitary cancer	2D12	Pituitary tissue	2.37E-01	-1.49E-01	-4.99E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	5.41E-02	-1.85E-01	-5.71E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.43E-02	-1.72E-01	-8.09E-01
Polycythemia vera	2A20.4	Whole blood	8.64E-05	-1.55E-01	-9.66E-01
Pompe disease	5C51.3	Biceps muscle	4.80E-04	7.68E-01	1.85E+00
Preterm birth	KA21.4Z	Myometrium	2.42E-01	3.94E-01	1.24E+00
Prostate cancer	2C82	Prostate	4.78E-03	-1.74E-01	-2.18E-01
Psoriasis	EA90	Skin	7.25E-01	1.12E-01	3.32E-01
Rectal cancer	2B92	Rectal colon tissue	4.36E-02	-1.60E-01	-7.62E-01
Renal cancer	2C90-2C91	Kidney	3.14E-03	-1.01E+00	-1.48E+00
Retinoblastoma	2D02.2	Uvea	6.61E-06	1.45E+00	4.57E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.57E-07	4.35E-01	2.04E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	2.86E-01	-6.18E-02	-1.76E-01
Schizophrenia	6A20	Prefrontal cortex	6.84E-02	-3.10E-01	-5.79E-01
Schizophrenia	6A20	Superior temporal cortex	3.27E-02	-2.57E-01	-5.81E-01
Scleroderma	4A42.Z	Whole blood	1.44E-02	1.62E-01	1.23E+00
Seizure	8A60-8A6Z	Whole blood	6.52E-01	2.18E-01	4.01E-01
Sensitive skin	EK0Z	Skin	1.12E-01	1.96E-01	8.85E-01
Sepsis with septic shock	1G41	Whole blood	4.56E-01	1.01E-02	2.96E-02
Shwachman-Diamond syndrome	3A70.0	Bone marrow	9.09E-02	-1.17E-01	-2.63E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	7.58E-01	9.67E-02	3.06E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	6.63E-01	-3.65E-01	-6.01E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.14E-03	-3.02E-01	-2.41E+00
Skin cancer	2C30-2C3Z	Skin	7.56E-27	-7.42E-01	-1.46E+00
Thrombocythemia	3B63	Whole blood	8.20E-06	-2.89E-01	-1.64E+00
Thrombocytopenia	3B64	Whole blood	3.86E-01	3.70E-01	3.46E-01
Thyroid cancer	2D10	Thyroid	2.71E-08	-2.88E-01	-8.35E-01
Tibial muscular dystrophy	8C75	Muscle tissue	2.31E-05	8.61E-01	1.98E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	8.07E-01	-1.67E-01	-1.37E+00
Type 2 diabetes	5A11	Liver tissue	5.15E-01	-2.03E-02	-7.28E-02
Ureter cancer	2C92	Urothelium	2.84E-01	4.23E-02	1.57E-01
Uterine cancer	2C78	Endometrium tissue	5.85E-01	-2.16E-01	-3.55E-01
Vitiligo	ED63.0	Skin	2.63E-01	-1.12E-01	-6.00E-01