Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEDH7FP)

• DME Name: Corticosteroid 11-beta-dehydrogenase 2 (HSD11B2) DME Info
• Gene Name: HSD11B2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.56E-01	4.09E-03	1.80E-02
Alopecia	ED70	Skin from scalp	2.74E-02	1.57E-01	4.21E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.14E-04	2.85E-01	7.34E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.81E-02	1.79E-01	1.25E+00
Aortic stenosis	BB70	Calcified aortic valve	5.24E-01	2.10E-02	1.04E-01
Apnea	7A40	Hyperplastic tonsil	3.52E-03	-9.35E-01	-1.73E+00
Arthropathy	FA00-FA5Z	Peripheral blood	7.05E-01	1.09E-01	6.21E-01
Asthma	CA23	Nasal and bronchial airway	2.11E-07	1.71E+00	1.22E+00
Atopic dermatitis	EA80	Skin	1.70E-05	6.09E-01	2.44E+00
Autism	6A02	Whole blood	9.31E-01	9.73E-03	4.09E-02
Autoimmune uveitis	9A96	Peripheral monocyte	2.32E-01	-1.36E-01	-6.19E-01
Autosomal dominant monocytopenia	4B04	Whole blood	7.75E-01	-7.95E-02	-4.62E-01
Bacterial infection of gingival	1C1H	Gingival tissue	6.72E-10	-3.27E-01	-8.46E-01
Batten disease	5C56.1	Whole blood	7.83E-02	1.57E-01	1.17E+00
Behcet's disease	4A62	Peripheral blood	6.37E-01	5.05E-02	1.67E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	2.86E-02	-9.72E-02	-4.94E-01
Bladder cancer	2C94	Bladder tissue	8.23E-01	-1.81E-01	-3.80E-01
Breast cancer	2C60-2C6Z	Breast tissue	3.84E-18	3.39E-01	5.75E-01
Cardioembolic stroke	8B11.20	Whole blood	5.85E-01	6.29E-02	2.24E-01
Cervical cancer	2C77	Cervical tissue	4.63E-02	-2.01E-01	-5.38E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.94E-01	2.30E-02	7.32E-02
Chronic hepatitis C	1E51.1	Whole blood	2.47E-01	1.13E-01	6.40E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	5.63E-02	-2.01E-01	-4.14E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	3.74E-01	4.94E-04	1.12E-03
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	8.64E-01	-2.32E-01	-1.12E+00
Colon cancer	2B90	Colon tissue	6.70E-187	-2.87E+00	-5.70E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	7.92E-01	-1.51E-02	-1.39E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	5.52E-01	2.24E-02	7.67E-02
Endometriosis	GA10	Endometrium tissue	2.82E-02	-1.61E+00	-7.34E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	8.83E-01	1.10E-02	5.99E-02
Familial hypercholesterolemia	5C80.00	Whole blood	1.85E-01	-1.56E-02	-7.21E-02
Gastric cancer	2B72	Gastric tissue	4.67E-01	5.65E-01	5.44E-01
Glioblastopma	2A00.00	Nervous tissue	8.70E-17	9.23E-02	2.05E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	5.31E-01	-6.84E-01	-6.69E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	5.90E-05	-4.76E-01	-1.86E+00
Head and neck cancer	2D42	Head and neck tissue	4.37E-03	-2.38E-01	-5.06E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	2.12E-01	-1.75E-01	-3.88E-01
Huntington's disease	8A01.10	Whole blood	4.15E-01	1.54E-03	1.26E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	4.66E-02	4.57E-01	1.34E+00
Immunodeficiency	4A00-4A20	Peripheral blood	1.95E-01	3.61E-02	3.18E-01
Influenza	1E30	Whole blood	8.09E-03	3.42E-01	2.43E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.52E-02	-1.05E+00	-2.44E+00
Intracranial aneurysm	8B01.0	Intracranial artery	7.18E-03	-3.95E-01	-1.02E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.45E-02	-5.61E-01	-9.40E-01
Ischemic stroke	8B11	Peripheral blood	1.42E-01	1.24E-01	6.49E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.91E-01	8.55E-02	2.53E-01
Lateral sclerosis	8B60.4	Skin	7.53E-02	1.39E-01	2.18E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	8.29E-01	5.69E-02	1.90E-01
Liver cancer	2C12.0	Liver tissue	3.42E-05	5.59E-02	1.61E-01
Liver failure	DB99.7-DB99.8	Liver tissue	4.79E-01	-1.31E-01	-4.33E-01
Lung cancer	2C25	Lung tissue	1.08E-02	-4.09E-02	-7.60E-02
Lupus erythematosus	4A40	Whole blood	7.23E-01	-1.82E-02	-5.87E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	1.29E-01	-8.43E-02	-4.13E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.19E-01	1.92E-02	6.94E-02
Melanoma	2C30	Skin	8.10E-04	-2.50E+00	-1.25E+00
Multiple myeloma	2A83.1	Peripheral blood	4.75E-01	1.37E-02	6.51E-02
Multiple myeloma	2A83.1	Bone marrow	4.05E-02	1.45E-01	8.96E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.15E-01	-2.26E-01	-6.33E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	3.92E-02	-8.58E-02	-4.40E-01
Myelofibrosis	2A20.2	Whole blood	1.44E-01	7.85E-02	6.22E-01
Myocardial infarction	BA41-BA50	Peripheral blood	1.34E-02	6.77E-02	2.29E-01
Myopathy	8C70.6	Muscle tissue	4.66E-03	2.06E-01	1.28E+00
Neonatal sepsis	KA60	Whole blood	7.05E-01	-4.69E-03	-1.84E-02
Neuroectodermal tumour	2A00.11	Brain stem tissue	3.58E-05	3.46E-01	7.05E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.59E-01	3.18E-01	7.64E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	8.86E-01	-3.12E-02	-1.45E-01
Olive pollen allergy	CA08.00	Peripheral blood	5.25E-01	-4.15E-03	-2.17E-02
Oral cancer	2B6E	Oral tissue	2.98E-02	-3.17E-01	-2.27E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	6.99E-01	-1.12E-01	-3.09E-01
Osteoporosis	FB83.1	Bone marrow	6.77E-01	1.20E-02	1.66E-01
Ovarian cancer	2C73	Ovarian tissue	7.65E-01	-1.96E-01	-2.33E-01
Pancreatic cancer	2C10	Pancreas	1.50E-02	4.54E-01	6.06E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	7.16E-01	-4.60E-02	-2.36E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	8.27E-01	4.66E-02	2.85E-01
Pituitary cancer	2D12	Pituitary tissue	6.10E-02	1.86E-01	5.57E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.45E-01	3.13E-01	1.03E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	7.81E-01	-3.89E-02	-2.27E-01
Polycythemia vera	2A20.4	Whole blood	5.04E-08	1.06E-01	9.54E-01
Pompe disease	5C51.3	Biceps muscle	9.80E-01	1.21E-01	2.53E-01
Preterm birth	KA21.4Z	Myometrium	2.31E-01	2.60E-01	1.02E+00
Prostate cancer	2C82	Prostate	9.43E-01	-3.44E-01	-3.82E-01
Psoriasis	EA90	Skin	1.11E-05	-3.97E-01	-6.06E-01
Rectal cancer	2B92	Rectal colon tissue	3.06E-14	-2.00E+00	-8.67E+00
Renal cancer	2C90-2C91	Kidney	1.38E-05	-3.89E+00	-2.71E+00
Retinoblastoma	2D02.2	Uvea	4.83E-01	-7.28E-03	-5.23E-02
Rheumatoid arthritis	FA20	Synovial tissue	1.07E-01	-2.23E-01	-4.62E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	9.07E-02	-5.03E-02	-9.71E-02
Schizophrenia	6A20	Prefrontal cortex	2.03E-01	5.03E-02	2.08E-01
Schizophrenia	6A20	Superior temporal cortex	9.54E-01	4.58E-02	2.60E-01
Scleroderma	4A42.Z	Whole blood	8.99E-01	-9.07E-03	-7.14E-02
Seizure	8A60-8A6Z	Whole blood	6.69E-02	4.66E-02	2.31E-01
Sensitive skin	EK0Z	Skin	3.06E-01	-3.61E-01	-5.29E-01
Sepsis with septic shock	1G41	Whole blood	8.23E-03	3.69E-02	1.24E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	9.92E-03	3.32E-01	1.24E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.12E-01	1.62E-01	1.09E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	4.10E-01	1.84E-01	5.35E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	3.05E-02	7.41E-01	1.74E+00
Skin cancer	2C30-2C3Z	Skin	1.34E-99	-2.18E+00	-2.69E+00
Thrombocythemia	3B63	Whole blood	2.98E-02	8.05E-02	6.32E-01
Thrombocytopenia	3B64	Whole blood	2.48E-01	1.30E-02	6.45E-02
Thyroid cancer	2D10	Thyroid	5.86E-29	-1.46E+00	-1.93E+00
Tibial muscular dystrophy	8C75	Muscle tissue	6.58E-07	7.98E-01	2.48E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.18E-01	1.71E-01	7.11E-01
Type 2 diabetes	5A11	Liver tissue	1.65E-01	-1.77E-01	-1.16E+00
Ureter cancer	2C92	Urothelium	3.53E-01	-3.29E-02	-1.72E-01
Uterine cancer	2C78	Endometrium tissue	9.29E-23	-1.72E+00	-1.14E+00
Vitiligo	ED63.0	Skin	9.07E-01	-4.38E-01	-5.01E-01