Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEE5M8O)

• DME Name: Alcohol dehydrogenase class-I alpha (ADH1A) DME Info
• Gene Name: ADH1A

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	9.34E-07	7.57E-02	4.90E-01
Alopecia	ED70	Skin from scalp	5.10E-02	4.03E-02	1.77E-01
Alzheimer's disease	8A20	Entorhinal cortex	6.96E-01	-4.11E-02	-2.10E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.32E-01	-2.62E-01	-1.10E+00
Aortic stenosis	BB70	Calcified aortic valve	7.95E-01	-9.40E-02	-3.37E-01
Apnea	7A40	Hyperplastic tonsil	6.27E-01	-2.41E-01	-5.40E-01
Arthropathy	FA00-FA5Z	Peripheral blood	4.97E-01	1.66E-02	1.03E-01
Asthma	CA23	Nasal and bronchial airway	7.75E-01	-3.05E-02	-4.63E-02
Atopic dermatitis	EA80	Skin	1.99E-01	-9.81E-02	-7.09E-01
Autism	6A02	Whole blood	2.07E-02	-7.33E-02	-3.25E-01
Autoimmune uveitis	9A96	Peripheral monocyte	7.82E-01	-6.07E-02	-6.26E-01
Autosomal dominant monocytopenia	4B04	Whole blood	9.58E-01	2.59E-02	1.14E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.97E-01	2.15E-02	7.72E-02
Batten disease	5C56.1	Whole blood	2.28E-01	6.97E-02	4.57E-01
Behcet's disease	4A62	Peripheral blood	1.65E-01	-1.41E-01	-7.60E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.88E-01	3.56E-02	1.67E-01
Bladder cancer	2C94	Bladder tissue	9.11E-05	3.52E-01	2.15E+00
Breast cancer	2C60-2C6Z	Breast tissue	9.68E-70	-8.48E-01	-1.57E+00
Cardioembolic stroke	8B11.20	Whole blood	1.67E-01	2.78E-02	1.89E-01
Cervical cancer	2C77	Cervical tissue	1.31E-02	2.35E-01	7.56E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	2.15E-01	3.42E-02	1.86E-01
Chronic hepatitis C	1E51.1	Whole blood	7.12E-01	1.71E-02	1.75E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.23E-02	7.64E-02	4.03E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	6.65E-02	-1.13E-01	-4.38E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	5.12E-04	-3.37E-01	-1.49E+00
Colon cancer	2B90	Colon tissue	2.61E-57	-1.35E+00	-1.95E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.04E-01	-1.73E-01	-1.22E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	7.84E-01	-4.21E-03	-3.04E-02
Endometriosis	GA10	Endometrium tissue	1.01E-03	1.42E-01	5.18E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	4.40E-01	-6.55E-02	-4.78E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.81E-01	-1.00E-01	-5.52E-01
Gastric cancer	2B72	Gastric tissue	1.93E-01	-6.84E-01	-2.01E+00
Glioblastopma	2A00.00	Nervous tissue	2.09E-01	-8.76E-03	-2.66E-02
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	9.78E-01	-5.70E-03	-1.80E-02
Glioma	2A00.0Y-2A00.0Z	White matter tissue	8.60E-04	-4.33E-01	-1.25E+00
Head and neck cancer	2D42	Head and neck tissue	6.94E-10	-2.61E-01	-5.45E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.94E-01	-8.55E-02	-3.15E-01
Huntington's disease	8A01.10	Whole blood	8.90E-01	0.00E+00	0.00E+00
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.87E-01	-7.50E-02	-8.57E-01
Immunodeficiency	4A00-4A20	Peripheral blood	9.52E-02	1.35E-01	8.85E-01
Influenza	1E30	Whole blood	2.91E-01	3.64E-02	2.64E-01
Interstitial cystitis	GC00.3	Bladder tissue	6.36E-01	-4.51E-02	-1.60E-01
Intracranial aneurysm	8B01.0	Intracranial artery	7.57E-01	-1.71E-03	-6.34E-03
Irritable bowel syndrome	DD91.0	Rectal colon tissue	6.89E-01	2.01E-01	4.09E-01
Ischemic stroke	8B11	Peripheral blood	1.13E-02	1.29E-01	9.67E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	4.44E-01	-2.25E-03	-8.75E-03
Lateral sclerosis	8B60.4	Skin	6.72E-01	3.53E-02	1.56E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	8.27E-01	1.22E-01	4.08E-01
Liver cancer	2C12.0	Liver tissue	4.80E-35	-1.60E+00	-2.77E+00
Liver failure	DB99.7-DB99.8	Liver tissue	2.71E-03	-4.53E+00	-5.78E+00
Lung cancer	2C25	Lung tissue	4.46E-39	-4.67E-01	-1.25E+00
Lupus erythematosus	4A40	Whole blood	3.80E-02	-1.29E-01	-3.95E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	3.67E-01	4.99E-02	2.32E-01
Major depressive disorder	6A70-6A7Z	Whole blood	6.25E-02	3.72E-02	1.26E-01
Melanoma	2C30	Skin	4.93E-01	2.33E-01	2.75E-01
Multiple myeloma	2A83.1	Peripheral blood	9.45E-01	9.98E-03	5.45E-02
Multiple myeloma	2A83.1	Bone marrow	1.52E-02	-4.85E-01	-1.16E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.64E-01	1.12E-01	3.28E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	4.96E-01	1.17E-02	6.35E-02
Myelofibrosis	2A20.2	Whole blood	1.22E-01	6.17E-02	3.99E-01
Myocardial infarction	BA41-BA50	Peripheral blood	4.42E-02	1.41E-01	3.57E-01
Myopathy	8C70.6	Muscle tissue	9.14E-02	8.99E-02	7.36E-01
Neonatal sepsis	KA60	Whole blood	5.86E-04	-1.58E-01	-6.59E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	9.48E-03	-4.04E-01	-1.33E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.68E-03	5.44E-01	2.25E+00
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.17E-01	-4.39E-01	-1.33E+00
Olive pollen allergy	CA08.00	Peripheral blood	8.25E-01	-3.08E-02	-1.57E-01
Oral cancer	2B6E	Oral tissue	1.39E-03	-3.27E-01	-9.50E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	3.89E-03	-3.12E-01	-1.63E+00
Osteoporosis	FB83.1	Bone marrow	4.02E-01	9.81E-02	1.16E+00
Ovarian cancer	2C73	Ovarian tissue	7.12E-01	9.41E-02	1.81E-01
Pancreatic cancer	2C10	Pancreas	4.42E-01	-1.33E-01	-1.41E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	6.80E-01	1.83E-02	8.61E-02
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	6.32E-01	-3.65E-02	-3.55E-01
Pituitary cancer	2D12	Pituitary tissue	3.99E-01	-2.15E-01	-7.75E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	6.81E-02	-4.26E-01	-1.21E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.35E-01	4.21E-03	2.48E-02
Polycythemia vera	2A20.4	Whole blood	3.42E-08	2.73E-01	1.49E+00
Pompe disease	5C51.3	Biceps muscle	1.56E-01	-8.51E-02	-1.92E-01
Preterm birth	KA21.4Z	Myometrium	3.46E-01	4.62E-02	2.82E-01
Prostate cancer	2C82	Prostate	1.37E-01	-7.99E-02	-1.77E-01
Psoriasis	EA90	Skin	2.10E-10	-3.09E-01	-7.80E-01
Rectal cancer	2B92	Rectal colon tissue	3.86E-04	-1.59E+00	-3.24E+00
Renal cancer	2C90-2C91	Kidney	4.51E-02	-1.70E-01	-7.11E-01
Retinoblastoma	2D02.2	Uvea	7.51E-01	-3.93E-02	-3.74E-01
Rheumatoid arthritis	FA20	Synovial tissue	5.22E-01	3.03E-02	1.09E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	3.43E-01	-7.33E-02	-2.13E-01
Schizophrenia	6A20	Prefrontal cortex	1.24E-01	2.00E-02	6.07E-02
Schizophrenia	6A20	Superior temporal cortex	6.07E-01	6.57E-02	4.53E-01
Scleroderma	4A42.Z	Whole blood	2.14E-01	-9.05E-03	-4.78E-02
Seizure	8A60-8A6Z	Whole blood	7.94E-01	-4.33E-02	-2.76E-01
Sensitive skin	EK0Z	Skin	5.04E-01	2.96E-02	2.69E-01
Sepsis with septic shock	1G41	Whole blood	1.18E-01	-8.52E-02	-2.98E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	2.09E-01	1.45E-01	4.81E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	8.71E-01	2.43E-02	9.75E-02
Simpson golabi behmel syndrome	LD2C	Adipose tissue	3.41E-02	-3.13E-01	-2.51E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.79E-01	1.68E-02	1.02E-01
Skin cancer	2C30-2C3Z	Skin	8.02E-05	-1.54E-01	-3.94E-01
Thrombocythemia	3B63	Whole blood	1.28E-04	2.01E-01	1.03E+00
Thrombocytopenia	3B64	Whole blood	6.27E-01	1.28E-02	7.21E-02
Thyroid cancer	2D10	Thyroid	5.12E-01	1.14E-02	4.16E-02
Tibial muscular dystrophy	8C75	Muscle tissue	3.50E-03	3.42E-01	1.24E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	7.10E-01	-1.32E-02	-1.20E-01
Type 2 diabetes	5A11	Liver tissue	3.68E-01	-2.21E-02	-1.37E-01
Ureter cancer	2C92	Urothelium	9.36E-01	1.94E-02	1.15E-01
Uterine cancer	2C78	Endometrium tissue	1.17E-06	1.61E-01	5.59E-01
Vitiligo	ED63.0	Skin	8.92E-01	-1.15E-01	-3.54E-01