Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEFI12S)

• DME Name: Vitamin D(3) 24-hydroxylase (CYP24A1) DME Info
• Gene Name: CYP24A1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	9.96E-03	-3.20E-02	-2.34E-01
Alopecia	ED70	Skin from scalp	1.34E-06	-8.74E-01	-1.18E+00
Alzheimer's disease	8A20	Entorhinal cortex	1.02E-02	-5.31E-02	-3.44E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.53E-01	1.20E-02	1.52E-01
Aortic stenosis	BB70	Calcified aortic valve	8.75E-01	-5.26E-02	-8.21E-02
Apnea	7A40	Hyperplastic tonsil	2.63E-01	8.14E-01	5.94E-01
Arthropathy	FA00-FA5Z	Peripheral blood	2.94E-01	8.69E-02	8.73E-01
Asthma	CA23	Nasal and bronchial airway	6.43E-01	-1.05E-01	-1.07E-01
Atopic dermatitis	EA80	Skin	2.64E-03	3.64E-01	3.66E+00
Autism	6A02	Whole blood	5.71E-03	1.09E-01	7.06E-01
Autoimmune uveitis	9A96	Peripheral monocyte	4.04E-01	-2.50E-02	-3.14E-01
Autosomal dominant monocytopenia	4B04	Whole blood	5.86E-01	5.96E-02	3.30E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.87E-18	1.72E+00	1.93E+00
Batten disease	5C56.1	Whole blood	6.91E-01	1.80E-01	6.62E-01
Behcet's disease	4A62	Peripheral blood	6.60E-01	-4.91E-02	-3.61E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	4.00E-01	-1.77E-02	-9.07E-02
Bladder cancer	2C94	Bladder tissue	1.47E-01	6.83E-02	9.52E-02
Breast cancer	2C60-2C6Z	Breast tissue	3.15E-02	-4.12E-02	-9.07E-02
Cardioembolic stroke	8B11.20	Whole blood	5.84E-01	-1.93E-02	-5.96E-02
Cervical cancer	2C77	Cervical tissue	5.68E-02	1.75E+00	9.19E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	4.09E-01	8.44E-04	4.41E-03
Chronic hepatitis C	1E51.1	Whole blood	2.26E-01	1.05E-01	1.06E+00
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.31E-01	3.72E-02	9.54E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	7.19E-01	5.64E-02	8.85E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	8.71E-02	1.92E+00	1.43E+00
Colon cancer	2B90	Colon tissue	3.67E-17	1.08E-01	4.74E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.86E-01	-3.94E-02	-1.49E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	3.75E-01	4.82E-02	3.19E-01
Endometriosis	GA10	Endometrium tissue	2.14E-02	1.40E-01	5.55E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	5.85E-01	-1.15E-01	-1.17E+00
Familial hypercholesterolemia	5C80.00	Whole blood	2.92E-03	-2.74E-01	-1.70E+00
Gastric cancer	2B72	Gastric tissue	1.44E-03	6.95E-02	1.21E+00
Glioblastopma	2A00.00	Nervous tissue	1.79E-04	-3.69E-02	-9.61E-02
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	6.51E-04	-1.18E-01	-6.36E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.83E-02	4.15E-01	8.25E-01
Head and neck cancer	2D42	Head and neck tissue	2.18E-21	1.16E+00	1.72E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.06E-01	-5.30E-02	-3.30E-01
Huntington's disease	8A01.10	Whole blood	2.47E-01	-4.76E-03	-3.58E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	6.65E-03	8.11E-01	1.90E+00
Immunodeficiency	4A00-4A20	Peripheral blood	3.42E-01	1.29E-01	8.59E-01
Influenza	1E30	Whole blood	6.50E-02	3.20E-01	2.78E+00
Interstitial cystitis	GC00.3	Bladder tissue	6.02E-01	-1.09E-01	-1.40E-01
Intracranial aneurysm	8B01.0	Intracranial artery	4.72E-01	-2.21E-02	-1.30E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.56E-01	1.01E-01	2.65E-01
Ischemic stroke	8B11	Peripheral blood	6.46E-01	-2.57E-02	-1.64E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.26E-01	1.14E-02	2.75E-02
Lateral sclerosis	8B60.4	Skin	9.38E-01	-1.34E-01	-2.86E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	1.86E-01	-8.45E-03	-3.23E-02
Liver cancer	2C12.0	Liver tissue	1.08E-02	2.36E-02	1.61E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.14E-02	-1.63E-01	-1.20E+00
Lung cancer	2C25	Lung tissue	2.36E-114	1.49E+00	2.51E+00
Lupus erythematosus	4A40	Whole blood	1.14E-01	2.33E-02	9.32E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	5.98E-01	-6.07E-03	-3.28E-02
Major depressive disorder	6A70-6A7Z	Whole blood	5.00E-01	5.28E-02	1.81E-01
Melanoma	2C30	Skin	1.27E-01	-1.15E-01	-1.25E-01
Multiple myeloma	2A83.1	Peripheral blood	2.53E-01	-5.11E-02	-6.29E-01
Multiple myeloma	2A83.1	Bone marrow	3.95E-02	-8.78E-02	-8.04E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	5.15E-01	-4.80E-03	-2.29E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	9.64E-01	4.19E-02	3.25E-01
Myelofibrosis	2A20.2	Whole blood	2.41E-01	4.95E-02	4.13E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.87E-02	1.56E-01	2.51E-01
Myopathy	8C70.6	Muscle tissue	8.46E-01	4.99E-02	2.26E-01
Neonatal sepsis	KA60	Whole blood	4.92E-04	-7.82E-02	-4.85E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	6.66E-01	-5.14E-02	-3.60E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	9.09E-01	3.82E-02	3.43E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.04E-01	1.16E-01	7.47E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.58E-02	2.04E-01	3.31E+00
Oral cancer	2B6E	Oral tissue	9.22E-04	9.78E-01	9.00E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	6.90E-01	2.05E-02	1.51E-01
Osteoporosis	FB83.1	Bone marrow	5.10E-01	0.00E+00	0.00E+00
Ovarian cancer	2C73	Ovarian tissue	1.68E-10	1.55E-01	1.13E+00
Pancreatic cancer	2C10	Pancreas	4.29E-03	2.75E-02	8.16E-02
Parkinson's disease	8A00.0	Substantia nigra tissue	5.20E-02	-2.75E-02	-4.55E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	6.69E-01	-1.36E-02	-1.20E-01
Pituitary cancer	2D12	Pituitary tissue	5.44E-01	1.08E-02	6.45E-02
Pituitary gonadotrope tumour	2D12	Pituitary tissue	9.94E-01	-2.57E-02	-1.32E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.12E-01	1.38E-03	1.01E-02
Polycythemia vera	2A20.4	Whole blood	1.37E-05	8.03E-02	7.23E-01
Pompe disease	5C51.3	Biceps muscle	8.62E-02	-1.18E-01	-1.07E+00
Preterm birth	KA21.4Z	Myometrium	5.07E-01	-5.42E-02	-2.47E-01
Prostate cancer	2C82	Prostate	7.29E-01	1.85E-01	9.48E-02
Psoriasis	EA90	Skin	7.16E-35	8.57E-01	2.08E+00
Rectal cancer	2B92	Rectal colon tissue	1.04E-01	3.65E-02	1.61E-01
Renal cancer	2C90-2C91	Kidney	1.29E-01	-8.02E-01	-6.22E-01
Retinoblastoma	2D02.2	Uvea	8.19E-02	6.05E-02	6.67E-01
Rheumatoid arthritis	FA20	Synovial tissue	3.97E-01	-5.62E-02	-4.81E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.33E-01	6.11E-02	7.54E-02
Schizophrenia	6A20	Prefrontal cortex	5.53E-04	-9.76E-02	-5.23E-01
Schizophrenia	6A20	Superior temporal cortex	5.92E-01	-4.56E-02	-4.29E-01
Scleroderma	4A42.Z	Whole blood	9.68E-04	2.20E-01	1.63E+00
Seizure	8A60-8A6Z	Whole blood	4.44E-01	9.87E-02	6.56E-01
Sensitive skin	EK0Z	Skin	5.35E-01	4.39E-02	5.80E-01
Sepsis with septic shock	1G41	Whole blood	1.17E-08	-1.03E-01	-5.73E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	2.73E-01	-6.23E-02	-4.09E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.52E-02	1.51E-01	1.06E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	6.52E-01	-1.34E-02	-5.01E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	5.87E-02	4.71E-02	1.14E+00
Skin cancer	2C30-2C3Z	Skin	2.24E-08	1.41E-01	2.99E-01
Thrombocythemia	3B63	Whole blood	2.81E-01	5.77E-02	4.50E-01
Thrombocytopenia	3B64	Whole blood	2.13E-01	3.20E-01	1.51E+00
Thyroid cancer	2D10	Thyroid	4.91E-01	-1.58E-01	-1.68E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.06E-02	-1.18E-01	-8.90E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.63E-01	1.53E-01	1.11E+00
Type 2 diabetes	5A11	Liver tissue	6.58E-01	-4.61E-02	-4.10E-01
Ureter cancer	2C92	Urothelium	3.37E-01	-2.29E-02	-5.70E-02
Uterine cancer	2C78	Endometrium tissue	1.13E-04	5.44E-01	3.61E-01
Vitiligo	ED63.0	Skin	3.56E-03	3.17E-01	1.14E+00