Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEGKWJB)

• DME Name: Alpha-methylacyl-CoA racemase (AMACR) DME Info
• Gene Name: AMACR

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.12E-01	7.52E-03	3.88E-02
Alopecia	ED70	Skin from scalp	2.17E-01	-1.99E-03	-5.28E-03
Alzheimer's disease	8A20	Entorhinal cortex	9.28E-01	-1.12E-02	-5.32E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	5.28E-02	1.27E-01	6.88E-01
Aortic stenosis	BB70	Calcified aortic valve	8.87E-01	1.80E-02	5.96E-02
Apnea	7A40	Hyperplastic tonsil	9.22E-02	-1.58E-01	-1.28E+00
Arthropathy	FA00-FA5Z	Peripheral blood	2.58E-01	-2.72E-02	-1.07E-01
Asthma	CA23	Nasal and bronchial airway	7.43E-01	8.15E-02	1.37E-01
Atopic dermatitis	EA80	Skin	3.11E-05	-1.94E-01	-9.10E-01
Autism	6A02	Whole blood	8.78E-01	3.44E-02	1.77E-01
Autoimmune uveitis	9A96	Peripheral monocyte	3.32E-02	-2.03E-01	-1.32E+00
Autosomal dominant monocytopenia	4B04	Whole blood	8.26E-01	-1.24E-02	-7.67E-02
Bacterial infection of gingival	1C1H	Gingival tissue	6.85E-03	-8.87E-02	-2.89E-01
Batten disease	5C56.1	Whole blood	4.21E-01	3.45E-02	1.75E-01
Behcet's disease	4A62	Peripheral blood	5.79E-01	-4.25E-02	-1.69E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	9.29E-01	3.80E-02	2.63E-01
Bladder cancer	2C94	Bladder tissue	2.31E-02	8.78E-02	3.74E-01
Breast cancer	2C60-2C6Z	Breast tissue	7.56E-13	1.14E-01	4.24E-01
Cardioembolic stroke	8B11.20	Whole blood	1.73E-01	-7.92E-03	-3.77E-02
Cervical cancer	2C77	Cervical tissue	1.03E-03	-2.48E-01	-9.09E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	5.47E-01	-5.21E-02	-1.57E-01
Chronic hepatitis C	1E51.1	Whole blood	7.84E-01	4.39E-02	2.70E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	3.43E-01	-3.03E-02	-1.68E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.15E-02	1.21E-01	4.92E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	9.20E-01	7.97E-02	6.08E-01
Colon cancer	2B90	Colon tissue	2.17E-01	-3.94E-02	-1.31E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.33E-02	-1.38E-01	-1.42E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	1.98E-01	5.66E-02	2.99E-01
Endometriosis	GA10	Endometrium tissue	6.13E-01	-1.67E-03	-5.16E-03
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.02E-01	-5.76E-02	-2.73E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.12E-01	-1.57E-01	-7.06E-01
Gastric cancer	2B72	Gastric tissue	8.84E-01	1.83E-01	2.82E-01
Glioblastopma	2A00.00	Nervous tissue	8.80E-01	2.66E-02	8.40E-02
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	2.69E-01	-1.31E-01	-1.71E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	7.50E-07	-7.86E-01	-3.11E+00
Head and neck cancer	2D42	Head and neck tissue	3.31E-01	-2.73E-02	-1.07E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	9.39E-01	-2.58E-02	-1.44E-01
Huntington's disease	8A01.10	Whole blood	4.56E-01	-1.49E-03	-7.67E-03
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	6.52E-01	-2.68E-02	-1.22E+00
Immunodeficiency	4A00-4A20	Peripheral blood	2.60E-01	-8.79E-02	-7.77E-01
Influenza	1E30	Whole blood	4.30E-01	1.13E-01	1.07E+00
Interstitial cystitis	GC00.3	Bladder tissue	2.44E-01	0.00E+00	0.00E+00
Intracranial aneurysm	8B01.0	Intracranial artery	1.24E-02	-1.04E-01	-7.11E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.21E-01	-7.60E-02	-2.05E-01
Ischemic stroke	8B11	Peripheral blood	3.86E-01	-4.34E-02	-2.36E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	4.99E-01	-6.16E-03	-1.87E-02
Lateral sclerosis	8B60.4	Skin	4.78E-01	3.38E-03	1.15E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	2.67E-01	9.65E-02	6.54E-01
Liver cancer	2C12.0	Liver tissue	8.34E-03	-7.83E-02	-1.72E-01
Liver failure	DB99.7-DB99.8	Liver tissue	2.29E-01	-1.55E-01	-7.02E-01
Lung cancer	2C25	Lung tissue	7.29E-22	2.06E-01	8.20E-01
Lupus erythematosus	4A40	Whole blood	6.61E-01	-4.82E-03	-1.04E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	6.22E-01	2.18E-02	1.65E-01
Major depressive disorder	6A70-6A7Z	Whole blood	3.92E-01	-1.44E-02	-6.66E-02
Melanoma	2C30	Skin	7.80E-02	-6.84E-01	-7.17E-01
Multiple myeloma	2A83.1	Peripheral blood	1.36E-01	-2.00E-01	-8.49E-01
Multiple myeloma	2A83.1	Bone marrow	1.22E-01	-1.10E-01	-4.14E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	7.03E-01	1.20E-01	2.05E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	5.97E-01	-5.57E-03	-3.60E-02
Myelofibrosis	2A20.2	Whole blood	5.30E-01	1.00E-01	5.86E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.08E-01	5.01E-02	1.20E-01
Myopathy	8C70.6	Muscle tissue	5.28E-02	-1.65E-01	-6.96E-01
Neonatal sepsis	KA60	Whole blood	1.32E-05	-1.11E-01	-4.66E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.98E-06	8.79E-01	3.19E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	3.80E-01	-9.06E-02	-3.39E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.85E-01	7.14E-02	9.32E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.37E-01	7.77E-02	1.05E+00
Oral cancer	2B6E	Oral tissue	1.59E-02	-2.42E-01	-7.03E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	8.45E-02	-5.38E-01	-1.05E+00
Osteoporosis	FB83.1	Bone marrow	1.31E-01	1.68E-01	9.03E-01
Ovarian cancer	2C73	Ovarian tissue	5.35E-01	-7.81E-02	-2.56E-01
Pancreatic cancer	2C10	Pancreas	9.31E-02	-1.26E-01	-3.22E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	6.64E-01	0.00E+00	0.00E+00
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	5.11E-01	-6.31E-02	-4.45E-01
Pituitary cancer	2D12	Pituitary tissue	1.34E-03	4.06E-01	1.75E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.23E-02	2.34E-01	8.61E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.39E-01	-8.77E-02	-5.55E-01
Polycythemia vera	2A20.4	Whole blood	1.09E-01	-3.99E-02	-2.62E-01
Pompe disease	5C51.3	Biceps muscle	1.92E-03	-2.38E-01	-1.12E+00
Preterm birth	KA21.4Z	Myometrium	2.39E-01	-1.50E-01	-6.73E-01
Prostate cancer	2C82	Prostate	1.50E-26	2.26E+00	4.45E+00
Psoriasis	EA90	Skin	4.79E-10	3.27E-01	9.82E-01
Rectal cancer	2B92	Rectal colon tissue	1.15E-01	-1.23E-01	-1.03E+00
Renal cancer	2C90-2C91	Kidney	1.58E-01	4.01E-01	8.22E-01
Retinoblastoma	2D02.2	Uvea	5.07E-02	8.22E-02	7.65E-01
Rheumatoid arthritis	FA20	Synovial tissue	6.14E-04	-6.16E-01	-2.13E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	4.72E-01	-1.14E-02	-7.83E-02
Schizophrenia	6A20	Prefrontal cortex	3.32E-01	-3.26E-02	-1.44E-01
Schizophrenia	6A20	Superior temporal cortex	9.53E-01	-3.62E-02	-2.35E-01
Scleroderma	4A42.Z	Whole blood	5.98E-07	8.72E-01	3.86E+00
Seizure	8A60-8A6Z	Whole blood	3.09E-01	-7.09E-02	-4.21E-01
Sensitive skin	EK0Z	Skin	4.76E-01	0.00E+00	0.00E+00
Sepsis with septic shock	1G41	Whole blood	2.61E-01	-1.14E-02	-4.17E-02
Shwachman-Diamond syndrome	3A70.0	Bone marrow	8.07E-02	-1.46E-01	-1.37E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	5.87E-01	-3.22E-02	-1.66E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.54E-01	-1.18E-02	-1.63E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	6.28E-01	-1.68E-02	-1.22E-01
Skin cancer	2C30-2C3Z	Skin	1.48E-02	-4.35E-02	-8.08E-02
Thrombocythemia	3B63	Whole blood	4.22E-01	-7.89E-02	-5.36E-01
Thrombocytopenia	3B64	Whole blood	9.19E-02	-2.11E-01	-9.39E-01
Thyroid cancer	2D10	Thyroid	8.82E-03	7.21E-02	2.44E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.51E-08	-7.85E-01	-3.28E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	8.88E-01	6.92E-02	3.33E-01
Type 2 diabetes	5A11	Liver tissue	7.56E-01	-6.50E-02	-1.85E-01
Ureter cancer	2C92	Urothelium	1.65E-01	1.35E-01	5.56E-01
Uterine cancer	2C78	Endometrium tissue	6.49E-04	5.82E-02	2.04E-01
Vitiligo	ED63.0	Skin	3.70E-01	-6.51E-02	-2.73E-01