Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEGTU5I)

• DME Name: Short-chain dehydrogenase/reductase retSDR8 (DHRS9) DME Info
• Gene Name: DHRS9

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	4.41E-17	-1.23E+00	-1.08E+00
Alopecia	ED70	Skin from scalp	3.04E-04	3.43E-01	5.66E-01
Alzheimer's disease	8A20	Entorhinal cortex	5.88E-02	9.42E-02	2.14E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	7.46E-01	-1.02E-01	-2.09E-01
Aortic stenosis	BB70	Calcified aortic valve	5.96E-01	2.20E-01	2.56E-01
Apnea	7A40	Hyperplastic tonsil	2.32E-01	1.46E+00	1.09E+00
Arthropathy	FA00-FA5Z	Peripheral blood	2.13E-01	5.03E-03	8.42E-03
Asthma	CA23	Nasal and bronchial airway	5.94E-03	1.81E-01	3.37E-01
Atopic dermatitis	EA80	Skin	7.70E-01	-2.29E-02	-3.25E-02
Autism	6A02	Whole blood	5.11E-01	-8.51E-03	-1.11E-02
Autoimmune uveitis	9A96	Peripheral monocyte	2.73E-01	8.60E-01	4.06E+00
Autosomal dominant monocytopenia	4B04	Whole blood	4.99E-02	5.81E-01	5.47E-01
Bacterial infection of gingival	1C1H	Gingival tissue	6.09E-09	4.97E-01	7.31E-01
Batten disease	5C56.1	Whole blood	6.41E-01	3.23E-02	9.90E-02
Behcet's disease	4A62	Peripheral blood	1.52E-02	5.00E-01	8.57E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	6.63E-02	-2.55E-01	-6.47E-01
Bladder cancer	2C94	Bladder tissue	7.39E-04	1.38E-01	5.86E-01
Breast cancer	2C60-2C6Z	Breast tissue	1.49E-11	-3.72E-01	-4.14E-01
Cardioembolic stroke	8B11.20	Whole blood	1.60E-02	4.79E-01	7.20E-01
Cervical cancer	2C77	Cervical tissue	1.97E-02	-8.20E-01	-7.04E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	9.17E-01	4.73E-01	2.43E-01
Chronic hepatitis C	1E51.1	Whole blood	1.59E-02	1.19E-01	1.09E+00
Chronic obstructive pulmonary disease	CA22	Lung tissue	6.99E-02	1.69E-01	3.53E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	9.53E-02	-1.08E-01	-2.44E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	9.14E-01	-7.20E-01	-5.57E-01
Colon cancer	2B90	Colon tissue	1.56E-143	-4.40E+00	-5.01E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.87E-01	-3.15E-01	-1.16E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	7.66E-01	5.60E-01	4.04E-01
Endometriosis	GA10	Endometrium tissue	3.42E-03	2.77E-01	1.00E+00
Familial hypercholesterolemia	5C80.00	Peripheral blood	2.06E-01	-3.75E-02	-1.28E-01
Familial hypercholesterolemia	5C80.00	Whole blood	4.26E-01	-1.83E-01	-2.78E-01
Gastric cancer	2B72	Gastric tissue	7.34E-01	6.71E-03	4.51E-03
Glioblastopma	2A00.00	Nervous tissue	6.35E-04	-2.82E-01	-4.35E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	5.52E-01	-5.33E-01	-9.01E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	6.55E-02	-2.02E+00	-9.90E-01
Head and neck cancer	2D42	Head and neck tissue	4.80E-33	-3.05E+00	-1.86E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	6.97E-02	-2.49E-01	-9.44E-01
Huntington's disease	8A01.10	Whole blood	2.44E-01	-2.19E-01	-4.94E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	9.17E-01	-2.19E-01	-2.62E-01
Immunodeficiency	4A00-4A20	Peripheral blood	1.29E-02	1.56E-01	3.53E+00
Influenza	1E30	Whole blood	4.56E-01	6.84E-01	9.06E-01
Interstitial cystitis	GC00.3	Bladder tissue	4.13E-03	1.42E+00	1.46E+01
Intracranial aneurysm	8B01.0	Intracranial artery	3.67E-03	1.04E+00	1.95E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	9.20E-03	1.96E-01	3.35E-01
Ischemic stroke	8B11	Peripheral blood	5.88E-01	-1.12E-01	-2.20E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	8.71E-02	-3.74E-01	-3.17E-01
Lateral sclerosis	8B60.4	Skin	9.28E-01	3.23E-02	2.28E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	7.45E-01	1.40E-01	3.95E-01
Liver cancer	2C12.0	Liver tissue	2.10E-02	6.80E-03	1.92E-02
Liver failure	DB99.7-DB99.8	Liver tissue	6.63E-06	1.67E+00	6.72E+00
Lung cancer	2C25	Lung tissue	2.79E-04	-2.16E-01	-2.99E-01
Lupus erythematosus	4A40	Whole blood	1.18E-15	1.22E+00	9.97E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	1.10E-01	-8.41E-02	-2.28E-01
Major depressive disorder	6A70-6A7Z	Whole blood	3.30E-01	7.86E-02	1.24E-01
Melanoma	2C30	Skin	9.98E-03	-1.48E+00	-9.12E-01
Multiple myeloma	2A83.1	Peripheral blood	8.31E-03	1.80E-01	1.34E+00
Multiple myeloma	2A83.1	Bone marrow	3.42E-11	5.56E-01	3.06E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.70E-01	2.61E-01	4.99E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	3.23E-16	5.68E-01	2.09E+00
Myelofibrosis	2A20.2	Whole blood	1.50E-01	2.26E-01	4.59E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.86E-01	7.67E-01	4.84E-01
Myopathy	8C70.6	Muscle tissue	2.53E-06	5.29E-01	4.27E+00
Neonatal sepsis	KA60	Whole blood	7.23E-17	1.57E+00	1.93E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	3.64E-11	-2.37E+00	-6.60E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	8.66E-02	3.26E-01	4.29E+00
Obesity related type 2 diabetes	5A11	Omental adipose tissue	6.74E-01	3.25E-01	5.74E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.88E-01	1.22E+00	1.06E+00
Oral cancer	2B6E	Oral tissue	2.95E-01	-6.06E-01	-4.84E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	3.60E-01	-3.63E-01	-5.17E-01
Osteoporosis	FB83.1	Bone marrow	3.34E-01	-1.12E-01	-1.40E-01
Ovarian cancer	2C73	Ovarian tissue	5.45E-04	8.65E-02	3.69E-01
Pancreatic cancer	2C10	Pancreas	7.12E-07	1.53E+00	1.85E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	6.26E-01	3.64E-01	5.33E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	4.91E-05	8.25E-01	1.87E+00
Pituitary cancer	2D12	Pituitary tissue	9.29E-03	3.08E-01	8.21E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.60E-03	1.01E+00	2.96E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	9.45E-01	7.30E-04	3.75E-03
Polycythemia vera	2A20.4	Whole blood	1.11E-01	-4.92E-02	-9.58E-02
Pompe disease	5C51.3	Biceps muscle	7.30E-03	1.78E+00	2.11E+00
Preterm birth	KA21.4Z	Myometrium	1.71E-01	-3.21E-01	-1.25E+00
Prostate cancer	2C82	Prostate	1.77E-01	-2.11E-01	-5.22E-01
Psoriasis	EA90	Skin	1.46E-15	1.40E+00	1.71E+00
Rectal cancer	2B92	Rectal colon tissue	1.23E-07	-2.45E+00	-5.01E+00
Renal cancer	2C90-2C91	Kidney	1.16E-04	3.08E-01	9.75E-01
Retinoblastoma	2D02.2	Uvea	2.43E-01	-3.66E-01	-1.91E+00
Rheumatoid arthritis	FA20	Synovial tissue	7.04E-01	9.93E-02	1.92E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.21E-01	-5.25E-02	-1.83E-01
Schizophrenia	6A20	Prefrontal cortex	2.60E-01	5.63E-02	1.18E-01
Schizophrenia	6A20	Superior temporal cortex	2.24E-01	3.05E-02	2.15E-01
Scleroderma	4A42.Z	Whole blood	8.74E-02	4.28E-01	6.79E-01
Seizure	8A60-8A6Z	Whole blood	1.82E-01	2.69E-01	2.30E-01
Sensitive skin	EK0Z	Skin	6.03E-01	8.40E-02	2.16E-01
Sepsis with septic shock	1G41	Whole blood	6.96E-88	2.37E+00	3.05E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.51E-01	3.70E-01	5.48E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	5.49E-03	2.34E-01	1.60E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	4.29E-01	1.40E-01	8.33E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.47E-03	9.06E-01	2.97E+00
Skin cancer	2C30-2C3Z	Skin	1.11E-20	-7.33E-01	-7.78E-01
Thrombocythemia	3B63	Whole blood	7.66E-01	-5.36E-02	-1.07E-01
Thrombocytopenia	3B64	Whole blood	2.44E-01	4.93E-01	8.58E-01
Thyroid cancer	2D10	Thyroid	5.89E-03	4.96E-01	3.89E-01
Tibial muscular dystrophy	8C75	Muscle tissue	2.86E-06	6.69E-01	2.73E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.90E-03	1.71E+00	3.35E+00
Type 2 diabetes	5A11	Liver tissue	9.10E-01	-5.09E-02	-2.07E-01
Ureter cancer	2C92	Urothelium	3.11E-01	2.12E-02	2.03E-02
Uterine cancer	2C78	Endometrium tissue	5.73E-03	3.11E-01	3.13E-01
Vitiligo	ED63.0	Skin	4.16E-01	2.27E-01	3.22E-01