Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEISPU8)

• DME Name: Arachidonate 12-lipoxygenase (ALOX12B) DME Info
• Gene Name: ALOX12B

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.08E-01	-6.65E-04	-3.29E-03
Alopecia	ED70	Skin from scalp	3.77E-03	5.59E-01	6.69E-01
Alzheimer's disease	8A20	Entorhinal cortex	4.29E-05	-1.81E-01	-5.25E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	9.29E-01	-4.96E-02	-4.26E-01
Aortic stenosis	BB70	Calcified aortic valve	8.95E-01	-3.62E-02	-6.38E-02
Apnea	7A40	Hyperplastic tonsil	2.90E-01	-2.57E+00	-1.86E+00
Arthropathy	FA00-FA5Z	Peripheral blood	7.69E-01	-1.31E-02	-8.98E-02
Asthma	CA23	Nasal and bronchial airway	3.94E-03	9.72E-02	3.07E-01
Atopic dermatitis	EA80	Skin	1.19E-02	-4.37E-01	-1.03E+00
Autism	6A02	Whole blood	5.76E-01	-1.22E-02	-6.49E-02
Autoimmune uveitis	9A96	Peripheral monocyte	4.97E-02	-1.15E-01	-7.27E-01
Autosomal dominant monocytopenia	4B04	Whole blood	3.07E-01	-5.59E-03	-3.90E-02
Bacterial infection of gingival	1C1H	Gingival tissue	9.39E-14	-1.02E+00	-1.34E+00
Batten disease	5C56.1	Whole blood	7.21E-01	-2.24E-02	-1.80E-01
Behcet's disease	4A62	Peripheral blood	3.61E-01	-1.58E-01	-5.04E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	7.20E-01	7.26E-02	3.05E-01
Bladder cancer	2C94	Bladder tissue	5.30E-04	2.80E-01	1.51E+00
Breast cancer	2C60-2C6Z	Breast tissue	6.41E-01	1.64E-02	5.22E-02
Cardioembolic stroke	8B11.20	Whole blood	4.77E-01	-9.20E-02	-5.42E-01
Cervical cancer	2C77	Cervical tissue	5.73E-03	-2.79E+00	-1.42E+00
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.52E-01	1.90E-02	7.42E-02
Chronic hepatitis C	1E51.1	Whole blood	8.47E-01	-2.20E-02	-1.54E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	3.00E-01	3.38E-02	1.85E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	8.60E-02	9.01E-02	4.62E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	7.66E-01	-1.21E-02	-8.64E-02
Colon cancer	2B90	Colon tissue	1.06E-03	-7.95E-02	-3.21E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	5.65E-01	-1.21E-01	-6.11E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	1.95E-01	1.85E-01	6.10E-01
Endometriosis	GA10	Endometrium tissue	1.06E-01	8.56E-02	4.08E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	4.63E-01	-3.43E-02	-2.51E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.44E-01	-1.60E-01	-6.41E-01
Gastric cancer	2B72	Gastric tissue	1.07E-01	3.30E-01	1.50E+00
Glioblastopma	2A00.00	Nervous tissue	3.77E-72	-5.18E-01	-1.22E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	2.49E-02	-2.75E-01	-4.89E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	8.96E-01	-3.54E-02	-2.32E-01
Head and neck cancer	2D42	Head and neck tissue	3.42E-19	1.75E+00	1.59E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	5.02E-02	-1.37E-01	-5.72E-01
Huntington's disease	8A01.10	Whole blood	2.33E-02	1.92E-01	9.35E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	4.07E-01	7.33E-03	6.85E-02
Immunodeficiency	4A00-4A20	Peripheral blood	8.13E-01	1.56E-02	1.33E-01
Influenza	1E30	Whole blood	2.53E-01	-3.62E-02	-9.21E-01
Interstitial cystitis	GC00.3	Bladder tissue	3.62E-02	1.01E-01	9.47E-01
Intracranial aneurysm	8B01.0	Intracranial artery	6.25E-01	9.50E-02	3.97E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	7.66E-01	1.80E-03	7.26E-03
Ischemic stroke	8B11	Peripheral blood	3.46E-02	1.83E-01	1.60E+00
Juvenile idiopathic arthritis	FA24	Peripheral blood	9.73E-01	-3.41E-02	-1.31E-01
Lateral sclerosis	8B60.4	Skin	9.16E-01	1.40E-02	7.73E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	6.46E-01	-4.79E-02	-3.49E-01
Liver cancer	2C12.0	Liver tissue	1.97E-03	-1.03E-01	-4.88E-01
Liver failure	DB99.7-DB99.8	Liver tissue	3.24E-02	-2.15E-01	-1.14E+00
Lung cancer	2C25	Lung tissue	1.50E-31	1.78E-01	8.39E-01
Lupus erythematosus	4A40	Whole blood	3.06E-01	-2.42E-02	-6.42E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	6.42E-01	-1.08E-02	-4.25E-02
Major depressive disorder	6A70-6A7Z	Whole blood	8.67E-01	-6.11E-02	-2.81E-01
Melanoma	2C30	Skin	9.74E-02	-9.10E-01	-5.31E-01
Multiple myeloma	2A83.1	Peripheral blood	3.33E-01	-6.10E-03	-3.79E-02
Multiple myeloma	2A83.1	Bone marrow	9.83E-01	-9.62E-02	-4.14E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.80E-01	6.04E-03	1.68E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	7.16E-02	-2.03E-02	-1.22E-01
Myelofibrosis	2A20.2	Whole blood	3.31E-01	1.38E-01	1.01E+00
Myocardial infarction	BA41-BA50	Peripheral blood	2.64E-01	1.41E-01	3.46E-01
Myopathy	8C70.6	Muscle tissue	1.21E-01	-2.08E-01	-8.15E-01
Neonatal sepsis	KA60	Whole blood	2.91E-01	-2.56E-02	-9.72E-02
Neuroectodermal tumour	2A00.11	Brain stem tissue	6.44E-02	-3.52E-01	-9.29E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.35E-01	-1.10E-01	-6.64E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	8.08E-02	9.31E-02	1.39E+00
Olive pollen allergy	CA08.00	Peripheral blood	1.96E-01	1.24E-02	1.40E-01
Oral cancer	2B6E	Oral tissue	8.45E-01	-2.37E-01	-1.52E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.23E-01	-8.36E-02	-3.14E-01
Osteoporosis	FB83.1	Bone marrow	2.88E-01	2.15E-01	1.40E+00
Ovarian cancer	2C73	Ovarian tissue	9.39E-03	5.60E-02	5.15E-01
Pancreatic cancer	2C10	Pancreas	1.09E-02	-2.46E-01	-7.78E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	8.64E-01	-5.32E-02	-2.62E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	6.66E-02	6.40E-02	4.37E-01
Pituitary cancer	2D12	Pituitary tissue	2.07E-01	1.74E-01	5.53E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	5.82E-01	-8.39E-02	-2.14E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	6.37E-01	3.50E-02	1.69E-01
Polycythemia vera	2A20.4	Whole blood	5.01E-04	8.05E-02	6.24E-01
Pompe disease	5C51.3	Biceps muscle	1.56E-01	-2.42E-02	-1.35E-01
Preterm birth	KA21.4Z	Myometrium	6.01E-01	-1.36E-01	-4.44E-01
Prostate cancer	2C82	Prostate	8.12E-01	-8.15E-02	-1.81E-01
Psoriasis	EA90	Skin	2.04E-42	1.99E+00	2.58E+00
Rectal cancer	2B92	Rectal colon tissue	9.61E-01	1.20E-01	4.66E-01
Renal cancer	2C90-2C91	Kidney	8.84E-01	9.88E-02	2.21E-01
Retinoblastoma	2D02.2	Uvea	1.24E-03	-1.25E-01	-1.05E+00
Rheumatoid arthritis	FA20	Synovial tissue	3.68E-01	-3.45E-01	-9.75E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	9.06E-01	-4.41E-02	-2.32E-01
Schizophrenia	6A20	Prefrontal cortex	3.23E-01	-4.68E-02	-1.22E-01
Schizophrenia	6A20	Superior temporal cortex	4.40E-01	-5.44E-02	-5.81E-01
Scleroderma	4A42.Z	Whole blood	4.65E-01	9.53E-02	5.25E-01
Seizure	8A60-8A6Z	Whole blood	8.88E-01	-1.56E-01	-6.96E-01
Sensitive skin	EK0Z	Skin	6.20E-01	2.22E-02	4.54E-02
Sepsis with septic shock	1G41	Whole blood	9.99E-02	-2.72E-02	-9.58E-02
Shwachman-Diamond syndrome	3A70.0	Bone marrow	6.71E-01	-1.43E-02	-3.61E-02
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	7.81E-01	-6.21E-02	-2.55E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	8.21E-02	8.12E-02	8.75E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	7.06E-01	5.15E-02	2.76E-01
Skin cancer	2C30-2C3Z	Skin	4.93E-74	-3.11E+00	-3.66E+00
Thrombocythemia	3B63	Whole blood	6.15E-02	1.61E-01	1.12E+00
Thrombocytopenia	3B64	Whole blood	2.60E-01	1.09E-01	2.43E-01
Thyroid cancer	2D10	Thyroid	2.65E-01	1.64E-02	7.18E-02
Tibial muscular dystrophy	8C75	Muscle tissue	3.09E-03	-3.34E-01	-1.30E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.08E-03	-6.59E-01	-7.62E+00
Type 2 diabetes	5A11	Liver tissue	1.35E-01	-1.25E-01	-1.05E+00
Ureter cancer	2C92	Urothelium	6.28E-01	8.41E-02	2.67E-01
Uterine cancer	2C78	Endometrium tissue	1.41E-01	3.35E-01	2.72E-01
Vitiligo	ED63.0	Skin	5.89E-01	-2.61E-01	-6.29E-01