Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEJHG19)

• DME Name: Peroxisomal multifunctional enzyme 2 (HSD17B4) DME Info
• Gene Name: HSD17B4

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	5.99E-01	3.82E-02	1.24E-01
Alopecia	ED70	Skin from scalp	5.16E-01	1.73E-02	8.71E-02
Alzheimer's disease	8A20	Entorhinal cortex	1.09E-06	1.30E-01	6.12E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	6.65E-02	1.06E-01	9.63E-01
Aortic stenosis	BB70	Calcified aortic valve	8.35E-01	-1.15E-01	-1.45E-01
Apnea	7A40	Hyperplastic tonsil	6.78E-01	2.46E-01	9.51E-01
Arthropathy	FA00-FA5Z	Peripheral blood	5.18E-01	4.51E-02	3.44E-01
Asthma	CA23	Nasal and bronchial airway	1.24E-01	-1.34E-03	-4.57E-03
Atopic dermatitis	EA80	Skin	2.02E-03	-1.66E-01	-1.81E+00
Autism	6A02	Whole blood	7.00E-03	1.02E-01	6.10E-01
Autoimmune uveitis	9A96	Peripheral monocyte	6.16E-01	2.22E-01	6.36E-01
Autosomal dominant monocytopenia	4B04	Whole blood	3.43E-02	6.74E-01	1.24E+00
Bacterial infection of gingival	1C1H	Gingival tissue	2.58E-05	-8.11E-02	-5.73E-01
Batten disease	5C56.1	Whole blood	2.95E-01	-1.13E-01	-1.64E+00
Behcet's disease	4A62	Peripheral blood	6.10E-01	2.27E-02	1.14E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	2.25E-01	3.54E-02	2.97E-01
Bladder cancer	2C94	Bladder tissue	1.07E-03	-4.44E-01	-2.10E+00
Breast cancer	2C60-2C6Z	Breast tissue	2.49E-03	6.37E-02	2.19E-01
Cardioembolic stroke	8B11.20	Whole blood	7.20E-04	1.11E-01	8.43E-01
Cervical cancer	2C77	Cervical tissue	9.66E-04	-3.62E-02	-2.26E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	2.74E-01	7.42E-02	2.19E-01
Chronic hepatitis C	1E51.1	Whole blood	2.22E-01	-1.22E-02	-5.35E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	4.55E-01	-4.16E-03	-3.51E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	6.73E-01	-1.74E-02	-9.46E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	5.15E-01	1.06E-01	5.61E-01
Colon cancer	2B90	Colon tissue	5.04E-01	1.47E-04	9.25E-04
Coronary artery disease	BA80-BA8Z	Peripheral blood	8.01E-01	8.64E-02	2.59E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	8.04E-01	-5.64E-02	-3.37E-01
Endometriosis	GA10	Endometrium tissue	3.68E-02	-9.40E-02	-6.22E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.97E-01	2.70E-02	2.33E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.12E-14	5.61E-01	1.91E+00
Gastric cancer	2B72	Gastric tissue	4.88E-01	3.05E-03	7.78E-03
Glioblastopma	2A00.00	Nervous tissue	3.99E-08	-7.96E-02	-3.22E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	2.23E-02	-1.37E-01	-2.56E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.09E-01	-1.23E-01	-5.41E-01
Head and neck cancer	2D42	Head and neck tissue	4.29E-24	-2.86E-01	-1.79E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	4.02E-01	9.71E-02	3.61E-01
Huntington's disease	8A01.10	Whole blood	9.39E-01	-1.13E-02	-4.70E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.00E-02	-4.57E-01	-2.34E+00
Immunodeficiency	4A00-4A20	Peripheral blood	3.79E-01	-4.43E-02	-5.09E-01
Influenza	1E30	Whole blood	9.20E-04	3.35E-01	4.69E+00
Interstitial cystitis	GC00.3	Bladder tissue	2.36E-03	-3.18E-01	-2.10E+00
Intracranial aneurysm	8B01.0	Intracranial artery	1.51E-02	2.07E-01	1.43E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	9.10E-01	-1.72E-02	-9.06E-02
Ischemic stroke	8B11	Peripheral blood	9.17E-01	9.58E-03	6.57E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	2.14E-01	-8.47E-02	-2.18E-01
Lateral sclerosis	8B60.4	Skin	2.81E-01	1.06E-01	8.32E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	7.17E-01	-3.47E-01	-9.13E-01
Liver cancer	2C12.0	Liver tissue	5.48E-01	-2.15E-02	-8.60E-02
Liver failure	DB99.7-DB99.8	Liver tissue	3.04E-04	-6.65E-01	-4.00E+00
Lung cancer	2C25	Lung tissue	2.76E-65	-3.24E-01	-1.84E+00
Lupus erythematosus	4A40	Whole blood	4.40E-05	2.42E-01	5.30E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	3.66E-01	-3.78E-02	-3.17E-01
Major depressive disorder	6A70-6A7Z	Whole blood	3.73E-01	7.08E-02	2.87E-01
Melanoma	2C30	Skin	4.84E-05	-2.57E-01	-9.10E-01
Multiple myeloma	2A83.1	Peripheral blood	1.55E-01	-1.33E-01	-6.21E-01
Multiple myeloma	2A83.1	Bone marrow	2.99E-05	4.73E-01	3.19E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	7.65E-01	-2.57E-02	-1.57E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	7.84E-01	6.07E-03	2.05E-02
Myelofibrosis	2A20.2	Whole blood	3.39E-01	-1.16E-01	-1.04E+00
Myocardial infarction	BA41-BA50	Peripheral blood	2.72E-03	-3.04E-01	-4.78E-01
Myopathy	8C70.6	Muscle tissue	1.15E-01	1.06E-01	9.16E-01
Neonatal sepsis	KA60	Whole blood	1.37E-04	1.65E-01	7.70E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	4.98E-01	1.30E-02	7.25E-02
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.45E-01	-1.02E-01	-6.15E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	8.73E-01	9.13E-02	4.07E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.99E-01	2.90E-01	6.66E-01
Oral cancer	2B6E	Oral tissue	9.53E-02	-1.07E-01	-3.48E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	2.74E-01	-1.91E-01	-4.82E-01
Osteoporosis	FB83.1	Bone marrow	8.24E-01	-8.34E-02	-3.76E-01
Ovarian cancer	2C73	Ovarian tissue	2.83E-01	4.15E-02	1.70E-01
Pancreatic cancer	2C10	Pancreas	3.26E-02	-8.53E-02	-7.90E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	5.38E-01	9.67E-02	5.37E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.81E-01	2.91E-02	2.26E-01
Pituitary cancer	2D12	Pituitary tissue	5.19E-01	-6.42E-02	-2.68E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	5.28E-01	-2.52E-02	-2.66E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	6.11E-01	6.17E-02	6.15E-01
Polycythemia vera	2A20.4	Whole blood	1.08E-02	-8.25E-02	-8.66E-01
Pompe disease	5C51.3	Biceps muscle	8.75E-01	-4.53E-02	-4.33E-01
Preterm birth	KA21.4Z	Myometrium	3.38E-01	8.03E-02	4.30E-01
Prostate cancer	2C82	Prostate	4.23E-06	5.16E-01	1.35E+00
Psoriasis	EA90	Skin	9.29E-23	2.02E-01	9.22E-01
Rectal cancer	2B92	Rectal colon tissue	3.63E-01	-1.84E-02	-2.91E-01
Renal cancer	2C90-2C91	Kidney	9.83E-01	8.75E-03	5.11E-02
Retinoblastoma	2D02.2	Uvea	3.56E-02	-7.95E-02	-9.54E-01
Rheumatoid arthritis	FA20	Synovial tissue	9.58E-02	-4.87E-01	-1.11E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	7.75E-01	2.31E-02	2.61E-01
Schizophrenia	6A20	Prefrontal cortex	7.42E-01	-1.98E-03	-1.51E-02
Schizophrenia	6A20	Superior temporal cortex	9.87E-01	2.10E-04	1.76E-03
Scleroderma	4A42.Z	Whole blood	1.21E-01	-8.33E-02	-8.23E-01
Seizure	8A60-8A6Z	Whole blood	8.49E-02	-6.11E-02	-6.28E-01
Sensitive skin	EK0Z	Skin	6.72E-01	4.14E-02	4.98E-01
Sepsis with septic shock	1G41	Whole blood	2.13E-02	-4.33E-02	-1.95E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	6.14E-02	-1.41E-01	-7.78E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	2.04E-01	-1.43E-01	-5.65E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.12E-01	3.53E-02	9.53E-02
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.90E-01	1.02E-01	6.66E-01
Skin cancer	2C30-2C3Z	Skin	4.42E-05	-1.56E-01	-7.97E-01
Thrombocythemia	3B63	Whole blood	1.16E-01	-6.86E-02	-6.41E-01
Thrombocytopenia	3B64	Whole blood	9.17E-01	-1.76E-01	-5.45E-01
Thyroid cancer	2D10	Thyroid	4.80E-14	-2.38E-01	-1.26E+00
Tibial muscular dystrophy	8C75	Muscle tissue	8.37E-03	-1.16E-01	-7.40E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.22E-01	5.64E-02	6.25E-01
Type 2 diabetes	5A11	Liver tissue	2.59E-01	1.69E-01	9.86E-01
Ureter cancer	2C92	Urothelium	7.65E-01	1.00E-01	2.22E-01
Uterine cancer	2C78	Endometrium tissue	1.02E-01	5.76E-02	2.12E-01
Vitiligo	ED63.0	Skin	7.84E-01	3.80E-02	1.92E-01