Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEMH6UB)

• DME Name: Lysosomal beta A mannosidase (MANBA) DME Info
• Gene Name: MANBA

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	5.76E-06	2.80E-01	7.71E-01
Alopecia	ED70	Skin from scalp	5.30E-02	1.92E-02	9.04E-02
Alzheimer's disease	8A20	Entorhinal cortex	3.45E-05	1.67E-01	6.51E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	6.51E-02	1.85E-01	6.89E-01
Aortic stenosis	BB70	Calcified aortic valve	8.25E-01	9.89E-02	8.83E-02
Apnea	7A40	Hyperplastic tonsil	4.34E-01	1.38E-01	4.44E-01
Arthropathy	FA00-FA5Z	Peripheral blood	5.87E-02	1.94E-01	8.85E-01
Asthma	CA23	Nasal and bronchial airway	1.53E-03	1.65E-01	3.92E-01
Atopic dermatitis	EA80	Skin	2.16E-01	-1.29E-01	-6.69E-01
Autism	6A02	Whole blood	2.86E-05	4.13E-01	1.33E+00
Autoimmune uveitis	9A96	Peripheral monocyte	3.60E-01	1.89E-01	8.92E-01
Autosomal dominant monocytopenia	4B04	Whole blood	2.70E-01	-1.89E-02	-5.61E-02
Bacterial infection of gingival	1C1H	Gingival tissue	9.76E-01	2.65E-02	9.29E-02
Batten disease	5C56.1	Whole blood	2.10E-01	2.41E-01	7.87E-01
Behcet's disease	4A62	Peripheral blood	9.55E-01	9.58E-03	4.65E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	7.86E-01	4.38E-02	2.48E-01
Bladder cancer	2C94	Bladder tissue	3.36E-04	-3.48E-01	-1.96E+00
Breast cancer	2C60-2C6Z	Breast tissue	5.48E-25	3.35E-01	8.07E-01
Cardioembolic stroke	8B11.20	Whole blood	7.00E-01	1.02E-01	5.98E-01
Cervical cancer	2C77	Cervical tissue	7.15E-02	-2.73E-01	-5.73E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	8.94E-01	-4.11E-03	-8.80E-03
Chronic hepatitis C	1E51.1	Whole blood	7.22E-01	1.40E-01	3.48E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	4.89E-01	4.71E-02	2.04E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	4.06E-01	-4.99E-02	-1.53E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	8.24E-02	-2.74E-01	-1.92E+00
Colon cancer	2B90	Colon tissue	1.75E-15	2.13E-01	6.32E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	8.37E-02	3.88E-01	1.33E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	8.79E-02	2.06E-01	4.89E-01
Endometriosis	GA10	Endometrium tissue	9.24E-01	2.32E-01	2.94E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	8.14E-01	-3.00E-02	-1.69E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.03E-14	1.38E+00	2.18E+00
Gastric cancer	2B72	Gastric tissue	1.74E-01	2.28E-01	9.79E-01
Glioblastopma	2A00.00	Nervous tissue	6.01E-52	4.26E-01	1.03E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	5.08E-06	-5.56E-01	-3.98E+01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	8.82E-01	-3.06E-01	-4.32E-01
Head and neck cancer	2D42	Head and neck tissue	1.28E-05	1.33E-01	3.86E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	5.93E-01	2.05E-01	4.36E-01
Huntington's disease	8A01.10	Whole blood	9.07E-01	9.35E-02	6.74E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.81E-01	8.88E-02	4.93E-01
Immunodeficiency	4A00-4A20	Peripheral blood	4.68E-02	-1.16E-01	-5.68E-01
Influenza	1E30	Whole blood	2.77E-01	-5.90E-01	-9.19E-01
Interstitial cystitis	GC00.3	Bladder tissue	2.94E-01	1.38E-02	2.85E-01
Intracranial aneurysm	8B01.0	Intracranial artery	2.98E-04	5.30E-01	2.52E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	3.87E-01	-1.87E-02	-9.05E-02
Ischemic stroke	8B11	Peripheral blood	3.46E-01	-7.13E-02	-2.05E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	3.67E-01	4.92E-02	2.15E-01
Lateral sclerosis	8B60.4	Skin	2.74E-02	-3.28E-01	-1.82E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	9.71E-01	1.11E-01	3.99E-01
Liver cancer	2C12.0	Liver tissue	4.72E-02	9.42E-03	2.40E-02
Liver failure	DB99.7-DB99.8	Liver tissue	5.89E-05	1.19E+00	3.07E+00
Lung cancer	2C25	Lung tissue	3.14E-06	-1.05E-01	-2.95E-01
Lupus erythematosus	4A40	Whole blood	5.08E-04	4.42E-01	5.40E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	2.94E-01	9.64E-03	5.65E-02
Major depressive disorder	6A70-6A7Z	Whole blood	1.62E-02	1.25E-01	5.42E-01
Melanoma	2C30	Skin	4.79E-01	6.57E-02	9.09E-02
Multiple myeloma	2A83.1	Peripheral blood	4.46E-01	1.89E-01	5.73E-01
Multiple myeloma	2A83.1	Bone marrow	9.47E-05	8.49E-01	2.78E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.02E-01	-6.52E-02	-3.15E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	4.62E-03	1.38E-01	3.72E-01
Myelofibrosis	2A20.2	Whole blood	3.56E-03	-2.48E-01	-1.66E+00
Myocardial infarction	BA41-BA50	Peripheral blood	9.14E-01	4.63E-02	9.18E-02
Myopathy	8C70.6	Muscle tissue	3.60E-02	3.62E-01	8.54E-01
Neonatal sepsis	KA60	Whole blood	1.36E-07	3.45E-01	7.36E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.69E-01	1.28E-01	5.58E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.46E-01	-1.36E-01	-5.00E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	4.87E-01	7.09E-03	2.56E-02
Olive pollen allergy	CA08.00	Peripheral blood	2.75E-01	-1.79E-01	-3.00E-01
Oral cancer	2B6E	Oral tissue	2.61E-03	4.49E-01	7.10E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	7.16E-01	-1.85E-01	-2.89E-01
Osteoporosis	FB83.1	Bone marrow	7.77E-01	-1.97E-01	-2.52E-01
Ovarian cancer	2C73	Ovarian tissue	9.29E-01	-9.87E-02	-2.03E-01
Pancreatic cancer	2C10	Pancreas	3.71E-03	3.83E-01	1.05E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	5.87E-02	3.76E-01	9.55E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.28E-01	9.59E-02	3.87E-01
Pituitary cancer	2D12	Pituitary tissue	2.41E-03	3.05E-01	9.57E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.98E-03	5.85E-01	1.65E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	3.13E-01	1.05E-01	6.01E-01
Polycythemia vera	2A20.4	Whole blood	1.75E-01	-2.93E-02	-1.80E-01
Pompe disease	5C51.3	Biceps muscle	8.73E-02	2.54E-01	1.37E+00
Preterm birth	KA21.4Z	Myometrium	1.85E-01	2.97E-01	9.06E-01
Prostate cancer	2C82	Prostate	1.84E-01	6.35E-01	7.90E-01
Psoriasis	EA90	Skin	9.74E-06	4.22E-02	1.07E-01
Rectal cancer	2B92	Rectal colon tissue	2.58E-01	-2.13E-01	-8.46E-01
Renal cancer	2C90-2C91	Kidney	2.95E-06	1.11E+00	3.09E+00
Retinoblastoma	2D02.2	Uvea	2.72E-05	1.13E+00	4.94E+00
Rheumatoid arthritis	FA20	Synovial tissue	2.51E-02	8.53E-01	1.50E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.26E-01	5.03E-02	3.59E-01
Schizophrenia	6A20	Prefrontal cortex	2.25E-01	-8.28E-02	-1.03E-01
Schizophrenia	6A20	Superior temporal cortex	6.36E-01	2.22E-02	1.86E-01
Scleroderma	4A42.Z	Whole blood	1.82E-01	-4.36E-03	-2.41E-02
Seizure	8A60-8A6Z	Whole blood	2.04E-01	-7.87E-02	-1.91E-01
Sensitive skin	EK0Z	Skin	7.93E-01	3.82E-02	3.26E-01
Sepsis with septic shock	1G41	Whole blood	9.66E-01	-4.27E-02	-9.65E-02
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.68E-02	-4.31E-01	-1.90E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.83E-01	-5.09E-02	-8.90E-02
Simpson golabi behmel syndrome	LD2C	Adipose tissue	5.21E-03	4.16E-01	2.96E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	6.24E-01	2.95E-02	1.97E-01
Skin cancer	2C30-2C3Z	Skin	7.11E-22	5.81E-01	1.20E+00
Thrombocythemia	3B63	Whole blood	1.30E-01	-1.20E-01	-8.24E-01
Thrombocytopenia	3B64	Whole blood	8.31E-01	-2.78E-01	-4.21E-01
Thyroid cancer	2D10	Thyroid	6.10E-01	-5.05E-02	-1.98E-01
Tibial muscular dystrophy	8C75	Muscle tissue	7.27E-05	5.18E-01	1.44E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	6.16E-02	3.56E-01	3.61E+00
Type 2 diabetes	5A11	Liver tissue	6.81E-01	-2.46E-02	-7.92E-02
Ureter cancer	2C92	Urothelium	2.31E-01	5.83E-02	2.46E-01
Uterine cancer	2C78	Endometrium tissue	6.61E-04	7.72E-02	1.59E-01
Vitiligo	ED63.0	Skin	9.41E-01	-1.22E-01	-3.80E-01