Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEN0GVQ)

• DME Name: Beta-HSD adrenal and gonadal type (HSD3B2) DME Info
• Gene Name: HSD3B2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	9.22E-01	-2.29E-02	-1.63E-01
Alopecia	ED70	Skin from scalp	2.05E-06	1.60E-01	6.06E-01
Alzheimer's disease	8A20	Entorhinal cortex	4.24E-02	-4.03E-02	-2.84E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	6.70E-01	-1.72E-02	-3.21E-01
Aortic stenosis	BB70	Calcified aortic valve	9.47E-01	-3.71E-02	-7.65E-02
Apnea	7A40	Hyperplastic tonsil	2.68E-01	-1.08E-01	-4.73E-01
Arthropathy	FA00-FA5Z	Peripheral blood	7.93E-01	6.17E-04	3.53E-03
Asthma	CA23	Nasal and bronchial airway	9.58E-01	2.40E-02	1.07E-01
Atopic dermatitis	EA80	Skin	9.58E-01	8.25E-02	3.71E-01
Autism	6A02	Whole blood	2.78E-01	-1.16E-02	-6.01E-02
Autoimmune uveitis	9A96	Peripheral monocyte	5.20E-01	-1.37E-01	-6.54E-01
Autosomal dominant monocytopenia	4B04	Whole blood	2.04E-01	-2.14E-02	-1.28E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.61E-03	9.03E-02	4.35E-01
Batten disease	5C56.1	Whole blood	8.66E-01	1.44E-02	1.26E-01
Behcet's disease	4A62	Peripheral blood	7.93E-01	2.88E-02	1.58E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	9.62E-01	2.53E-02	1.71E-01
Bladder cancer	2C94	Bladder tissue	1.21E-03	9.38E-01	1.94E+00
Breast cancer	2C60-2C6Z	Breast tissue	3.09E-22	-2.02E-01	-6.92E-01
Cardioembolic stroke	8B11.20	Whole blood	1.55E-03	1.42E-01	9.25E-01
Cervical cancer	2C77	Cervical tissue	9.40E-01	-2.09E-02	-5.02E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	4.84E-01	4.21E-02	2.43E-01
Chronic hepatitis C	1E51.1	Whole blood	1.13E-01	3.40E-02	3.05E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.87E-01	6.39E-02	3.88E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.04E-01	5.56E-02	3.35E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	3.45E-01	-7.19E-03	-7.61E-02
Colon cancer	2B90	Colon tissue	2.27E-24	-1.38E+00	-8.21E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	2.09E-01	-1.21E-01	-8.81E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	6.35E-01	-5.43E-02	-2.33E-01
Endometriosis	GA10	Endometrium tissue	1.18E-01	1.38E-01	4.91E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	8.90E-01	-2.49E-02	-2.51E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.05E-01	-1.68E-01	-8.71E-01
Gastric cancer	2B72	Gastric tissue	4.26E-01	-3.77E-01	-1.19E+00
Glioblastopma	2A00.00	Nervous tissue	8.73E-04	-8.94E-02	-3.66E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	7.28E-01	1.65E-02	2.14E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	7.12E-03	-1.58E-01	-7.73E-01
Head and neck cancer	2D42	Head and neck tissue	1.36E-01	-4.32E-02	-6.59E-02
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	8.36E-02	-6.46E-02	-2.30E-01
Huntington's disease	8A01.10	Whole blood	4.59E-01	-3.09E-03	-9.54E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	9.78E-01	-1.28E-02	-1.01E-01
Immunodeficiency	4A00-4A20	Peripheral blood	1.08E-01	3.13E-04	2.49E-03
Influenza	1E30	Whole blood	1.51E-01	1.94E-01	1.09E+00
Interstitial cystitis	GC00.3	Bladder tissue	3.87E-02	2.27E-01	1.57E+00
Intracranial aneurysm	8B01.0	Intracranial artery	9.17E-01	-6.58E-02	-3.81E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	7.96E-01	2.62E-02	3.21E-02
Ischemic stroke	8B11	Peripheral blood	3.83E-01	4.94E-03	2.83E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	2.16E-02	9.26E-02	4.40E-01
Lateral sclerosis	8B60.4	Skin	5.59E-01	5.55E-02	4.74E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	2.64E-01	-1.35E-01	-7.99E-01
Liver cancer	2C12.0	Liver tissue	1.16E-08	-2.42E-01	-1.28E+00
Liver failure	DB99.7-DB99.8	Liver tissue	1.47E-06	-4.97E-01	-4.25E+00
Lung cancer	2C25	Lung tissue	2.95E-01	2.66E-02	1.05E-01
Lupus erythematosus	4A40	Whole blood	8.99E-01	2.23E-02	8.17E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	5.86E-01	2.59E-02	1.63E-01
Major depressive disorder	6A70-6A7Z	Whole blood	7.68E-01	5.84E-03	2.57E-02
Melanoma	2C30	Skin	8.94E-04	-4.34E-01	-7.80E-01
Multiple myeloma	2A83.1	Peripheral blood	3.50E-02	1.57E-01	1.08E+00
Multiple myeloma	2A83.1	Bone marrow	2.59E-04	-7.99E-01	-2.24E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	7.40E-01	4.40E-03	1.75E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	4.17E-03	-1.36E-01	-7.58E-01
Myelofibrosis	2A20.2	Whole blood	4.92E-06	1.54E-01	9.12E-01
Myocardial infarction	BA41-BA50	Peripheral blood	1.85E-02	5.58E-02	2.77E-01
Myopathy	8C70.6	Muscle tissue	1.27E-01	-1.72E-01	-6.23E-01
Neonatal sepsis	KA60	Whole blood	1.12E-01	6.83E-02	3.91E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.81E-03	-5.03E-01	-1.46E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	9.36E-01	-1.37E-02	-8.32E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.17E-01	7.37E-02	7.80E-01
Olive pollen allergy	CA08.00	Peripheral blood	8.43E-01	-1.92E-02	-1.28E-01
Oral cancer	2B6E	Oral tissue	3.58E-04	-3.36E-01	-1.47E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	1.08E-01	-1.27E-01	-5.02E-01
Osteoporosis	FB83.1	Bone marrow	2.62E-01	2.60E-02	1.82E-01
Ovarian cancer	2C73	Ovarian tissue	1.08E-01	-1.78E-01	-6.52E-02
Pancreatic cancer	2C10	Pancreas	5.50E-02	-2.51E-01	-6.18E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	5.17E-01	2.00E-02	1.23E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	6.65E-01	9.02E-03	9.23E-02
Pituitary cancer	2D12	Pituitary tissue	4.53E-01	1.04E-01	1.16E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.85E-01	4.70E-02	2.56E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	3.38E-02	-7.73E-02	-6.31E-01
Polycythemia vera	2A20.4	Whole blood	3.89E-09	2.00E-01	1.30E+00
Pompe disease	5C51.3	Biceps muscle	6.54E-01	8.86E-03	4.78E-02
Preterm birth	KA21.4Z	Myometrium	1.28E-01	-2.08E-01	-1.85E+00
Prostate cancer	2C82	Prostate	9.70E-02	-1.70E-01	-7.62E-01
Psoriasis	EA90	Skin	8.88E-02	-5.38E-02	-3.16E-01
Rectal cancer	2B92	Rectal colon tissue	1.37E-01	-6.92E-01	-5.65E-01
Renal cancer	2C90-2C91	Kidney	3.63E-03	-3.38E-01	-1.33E+00
Retinoblastoma	2D02.2	Uvea	4.81E-01	-1.56E-01	-1.10E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.30E-02	-4.77E-01	-1.39E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	8.24E-01	-1.16E-02	-7.47E-02
Schizophrenia	6A20	Prefrontal cortex	2.39E-01	5.15E-02	2.14E-01
Schizophrenia	6A20	Superior temporal cortex	8.14E-01	-2.28E-02	-1.48E-01
Scleroderma	4A42.Z	Whole blood	1.75E-01	-1.60E-01	-9.59E-01
Seizure	8A60-8A6Z	Whole blood	6.17E-02	-7.94E-02	-3.90E-01
Sensitive skin	EK0Z	Skin	9.46E-01	5.27E-02	1.86E-01
Sepsis with septic shock	1G41	Whole blood	2.42E-01	2.13E-02	1.13E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.90E-01	2.63E-01	7.85E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.14E-01	9.87E-02	4.58E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	5.65E-01	-1.52E-02	-1.53E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	7.51E-01	-3.21E-02	-2.32E-01
Skin cancer	2C30-2C3Z	Skin	3.63E-05	1.15E-01	3.63E-01
Thrombocythemia	3B63	Whole blood	5.07E-04	1.82E-01	1.19E+00
Thrombocytopenia	3B64	Whole blood	4.19E-01	-1.09E-01	-5.65E-01
Thyroid cancer	2D10	Thyroid	4.82E-03	-7.82E-02	-4.39E-01
Tibial muscular dystrophy	8C75	Muscle tissue	5.77E-03	-2.35E-01	-1.08E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	6.37E-01	5.80E-02	6.07E+00
Type 2 diabetes	5A11	Liver tissue	1.43E-01	-6.28E-02	-3.40E-01
Ureter cancer	2C92	Urothelium	1.02E-01	9.90E-02	6.65E-01
Uterine cancer	2C78	Endometrium tissue	5.02E-03	1.49E-01	4.54E-01
Vitiligo	ED63.0	Skin	6.54E-01	-1.79E-02	-5.91E-02