Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DENV24I)

• DME Name: Nicotinamide riboside kinase 1 (NRK1) DME Info
• Gene Name: NMRK1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	9.47E-22	-4.42E-01	-1.17E+00
Alopecia	ED70	Skin from scalp	1.39E-05	2.23E-01	7.02E-01
Alzheimer's disease	8A20	Entorhinal cortex	5.28E-01	-7.62E-02	-1.99E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	7.70E-01	-1.23E-01	-5.95E-01
Aortic stenosis	BB70	Calcified aortic valve	5.01E-01	-1.99E-01	-2.87E-01
Apnea	7A40	Hyperplastic tonsil	8.88E-02	4.90E-01	2.13E+00
Arthropathy	FA00-FA5Z	Peripheral blood	1.05E-01	-1.64E-01	-3.77E-01
Asthma	CA23	Nasal and bronchial airway	3.08E-04	-1.13E-01	-3.10E-01
Atopic dermatitis	EA80	Skin	5.96E-01	-1.15E-01	-3.75E-01
Autism	6A02	Whole blood	1.16E-01	-1.27E-01	-2.39E-01
Autoimmune uveitis	9A96	Peripheral monocyte	9.03E-01	8.68E-02	4.77E-01
Autosomal dominant monocytopenia	4B04	Whole blood	8.31E-02	1.76E-01	4.44E-01
Bacterial infection of gingival	1C1H	Gingival tissue	6.39E-05	1.99E-01	5.81E-01
Batten disease	5C56.1	Whole blood	2.14E-01	-2.08E-01	-9.02E-01
Behcet's disease	4A62	Peripheral blood	5.87E-01	-3.92E-02	-1.39E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	4.60E-01	2.94E-03	8.06E-03
Bladder cancer	2C94	Bladder tissue	8.36E-04	-1.74E+00	-2.66E+00
Breast cancer	2C60-2C6Z	Breast tissue	3.81E-04	-1.41E-01	-3.85E-01
Cardioembolic stroke	8B11.20	Whole blood	2.41E-01	3.22E-02	8.00E-02
Cervical cancer	2C77	Cervical tissue	3.22E-04	-6.04E-01	-8.72E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.56E-01	-1.40E-01	-2.99E-01
Chronic hepatitis C	1E51.1	Whole blood	5.08E-01	-1.23E-01	-4.30E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	3.65E-02	-9.68E-02	-4.60E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.03E-02	-9.00E-02	-2.51E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	5.66E-01	-7.33E-02	-4.68E-01
Colon cancer	2B90	Colon tissue	5.00E-29	-2.84E-01	-1.05E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	5.21E-01	-6.58E-01	-7.22E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	1.55E-01	2.45E-01	4.37E-01
Endometriosis	GA10	Endometrium tissue	3.10E-03	3.20E-01	1.05E+00
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.29E-01	-7.28E-02	-2.53E-01
Familial hypercholesterolemia	5C80.00	Whole blood	7.04E-05	-5.15E-01	-9.42E-01
Gastric cancer	2B72	Gastric tissue	3.80E-01	-4.80E-01	-1.08E+00
Glioblastopma	2A00.00	Nervous tissue	7.58E-30	-3.41E-01	-7.82E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	2.62E-01	-2.85E-01	-9.44E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.51E-01	-2.45E-02	-6.11E-02
Head and neck cancer	2D42	Head and neck tissue	1.25E-24	-7.06E-01	-1.63E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.19E-01	1.33E-01	3.62E-01
Huntington's disease	8A01.10	Whole blood	9.03E-01	4.00E-02	1.26E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	5.90E-03	2.70E-01	1.48E+00
Immunodeficiency	4A00-4A20	Peripheral blood	9.86E-04	-3.10E-01	-3.67E+00
Influenza	1E30	Whole blood	8.23E-01	1.61E-01	3.48E-01
Interstitial cystitis	GC00.3	Bladder tissue	1.35E-02	-5.18E-01	-1.94E+00
Intracranial aneurysm	8B01.0	Intracranial artery	4.79E-01	-7.23E-02	-6.38E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.09E-01	-8.15E-02	-2.86E-01
Ischemic stroke	8B11	Peripheral blood	8.53E-01	-1.16E-01	-3.61E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	3.39E-01	6.83E-02	1.82E-01
Lateral sclerosis	8B60.4	Skin	4.51E-01	1.41E-01	7.11E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	6.19E-02	-2.52E-01	-8.04E-01
Liver cancer	2C12.0	Liver tissue	1.36E-14	-5.40E-01	-1.78E+00
Liver failure	DB99.7-DB99.8	Liver tissue	8.25E-02	2.31E-01	1.86E+00
Lung cancer	2C25	Lung tissue	7.86E-08	-1.18E-01	-4.89E-01
Lupus erythematosus	4A40	Whole blood	1.28E-01	5.64E-02	1.48E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	5.11E-01	1.57E-02	4.25E-02
Major depressive disorder	6A70-6A7Z	Whole blood	3.85E-01	-2.28E-02	-5.23E-02
Melanoma	2C30	Skin	7.00E-04	-3.30E-01	-5.71E-01
Multiple myeloma	2A83.1	Peripheral blood	5.20E-01	-1.03E-01	-3.34E-01
Multiple myeloma	2A83.1	Bone marrow	1.28E-05	6.36E-01	3.31E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.93E-01	-1.08E-02	-2.72E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.75E-01	-5.06E-03	-1.65E-02
Myelofibrosis	2A20.2	Whole blood	3.47E-04	-2.46E-01	-8.95E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.35E-04	-4.10E-01	-6.92E-01
Myopathy	8C70.6	Muscle tissue	8.59E-01	7.78E-02	3.32E-01
Neonatal sepsis	KA60	Whole blood	6.71E-01	-5.31E-02	-1.19E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	6.26E-01	3.42E-02	1.23E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	6.53E-01	-4.27E-02	-1.69E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.42E-01	9.24E-02	3.91E-01
Olive pollen allergy	CA08.00	Peripheral blood	2.45E-01	-1.77E-01	-5.27E-01
Oral cancer	2B6E	Oral tissue	2.13E-01	-1.09E-01	-3.66E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	3.78E-01	1.39E-01	5.93E-01
Osteoporosis	FB83.1	Bone marrow	3.75E-02	6.22E-01	1.42E+00
Ovarian cancer	2C73	Ovarian tissue	2.28E-02	-5.87E-01	-9.91E-01
Pancreatic cancer	2C10	Pancreas	2.88E-03	-3.18E-01	-1.17E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	1.60E-01	3.34E-01	9.97E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.97E-01	-3.30E-02	-1.18E-01
Pituitary cancer	2D12	Pituitary tissue	3.42E-06	-9.67E-01	-2.42E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.53E-06	-8.54E-01	-2.94E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	1.46E-01	-7.63E-02	-4.20E-01
Polycythemia vera	2A20.4	Whole blood	6.16E-04	-2.31E-01	-7.82E-01
Pompe disease	5C51.3	Biceps muscle	7.17E-02	3.11E-01	1.48E+00
Preterm birth	KA21.4Z	Myometrium	3.58E-01	1.81E-01	7.57E-01
Prostate cancer	2C82	Prostate	2.62E-01	-1.41E-02	-3.51E-02
Psoriasis	EA90	Skin	4.39E-01	-1.60E-02	-4.78E-02
Rectal cancer	2B92	Rectal colon tissue	8.60E-04	-4.09E-01	-2.51E+00
Renal cancer	2C90-2C91	Kidney	7.33E-01	6.82E-02	2.04E-01
Retinoblastoma	2D02.2	Uvea	3.39E-07	8.42E-01	3.19E+00
Rheumatoid arthritis	FA20	Synovial tissue	4.33E-02	1.20E-01	9.85E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	3.43E-02	6.05E-02	3.19E-01
Schizophrenia	6A20	Prefrontal cortex	9.47E-01	3.00E-02	7.96E-02
Schizophrenia	6A20	Superior temporal cortex	6.27E-01	-1.46E-03	-5.96E-03
Scleroderma	4A42.Z	Whole blood	6.32E-03	3.08E-01	8.43E-01
Seizure	8A60-8A6Z	Whole blood	5.04E-04	4.27E-01	1.15E+00
Sensitive skin	EK0Z	Skin	4.93E-01	-1.01E-01	-9.96E-01
Sepsis with septic shock	1G41	Whole blood	1.93E-19	4.23E-01	9.38E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	8.51E-01	-4.49E-02	-9.25E-02
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	7.06E-02	1.94E-01	1.21E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	3.14E-01	1.27E-02	2.64E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	9.32E-01	7.93E-03	5.84E-02
Skin cancer	2C30-2C3Z	Skin	2.10E-41	-4.99E-01	-1.35E+00
Thrombocythemia	3B63	Whole blood	4.45E-03	-1.83E-01	-6.35E-01
Thrombocytopenia	3B64	Whole blood	3.37E-01	-2.83E-01	-6.31E-01
Thyroid cancer	2D10	Thyroid	3.09E-01	2.48E-02	9.68E-02
Tibial muscular dystrophy	8C75	Muscle tissue	3.10E-03	-3.45E-01	-1.75E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.15E-02	-5.31E-01	-3.83E+00
Type 2 diabetes	5A11	Liver tissue	4.10E-01	-1.55E-01	-7.06E-01
Ureter cancer	2C92	Urothelium	4.47E-01	6.11E-02	1.56E-01
Uterine cancer	2C78	Endometrium tissue	4.58E-01	1.01E-01	1.62E-01
Vitiligo	ED63.0	Skin	6.69E-01	-3.86E-02	-9.88E-02