Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEOG15F)

• DME Name: Steroid 5-alpha-reductase 1 (SRD5A1) DME Info
• Gene Name: SRD5A1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	3.49E-02	-2.65E-01	-5.44E-01
Alopecia	ED70	Skin from scalp	8.62E-01	1.11E-01	3.06E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.79E-09	-6.51E-01	-9.39E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	5.44E-01	1.82E-01	4.52E-01
Aortic stenosis	BB70	Calcified aortic valve	1.23E-01	5.18E-01	9.47E-01
Apnea	7A40	Hyperplastic tonsil	3.94E-01	-1.27E-01	-3.02E-01
Arthropathy	FA00-FA5Z	Peripheral blood	8.86E-01	1.40E-01	5.09E-01
Asthma	CA23	Nasal and bronchial airway	3.09E-04	1.12E-01	1.84E-01
Atopic dermatitis	EA80	Skin	6.45E-02	5.12E-01	6.47E-01
Autism	6A02	Whole blood	1.47E-02	-2.03E-01	-7.10E-01
Autoimmune uveitis	9A96	Peripheral monocyte	1.78E-01	-3.47E-01	-7.95E-01
Autosomal dominant monocytopenia	4B04	Whole blood	7.75E-01	-1.60E-01	-3.42E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.02E-08	-2.28E-01	-8.60E-01
Batten disease	5C56.1	Whole blood	6.69E-01	7.68E-02	3.80E-01
Behcet's disease	4A62	Peripheral blood	3.81E-01	-3.49E-02	-1.19E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	3.88E-01	-4.75E-02	-1.50E-01
Bladder cancer	2C94	Bladder tissue	8.92E-05	1.04E+00	2.59E+00
Breast cancer	2C60-2C6Z	Breast tissue	2.48E-22	6.63E-01	5.73E-01
Cardioembolic stroke	8B11.20	Whole blood	3.28E-04	3.59E-01	1.33E+00
Cervical cancer	2C77	Cervical tissue	7.74E-05	-6.05E-01	-1.29E+00
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	3.31E-01	8.30E-02	9.74E-02
Chronic hepatitis C	1E51.1	Whole blood	6.51E-01	-2.88E-01	-6.16E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	3.81E-01	8.43E-03	3.12E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	7.28E-07	-4.36E-01	-9.78E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	4.34E-01	1.26E-01	5.26E-01
Colon cancer	2B90	Colon tissue	1.24E-53	6.30E-01	1.72E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	7.41E-01	5.40E-01	4.48E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.50E-02	-3.27E-01	-9.60E-01
Endometriosis	GA10	Endometrium tissue	3.41E-01	-2.23E-01	-2.29E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	2.08E-01	-1.55E-01	-4.97E-01
Familial hypercholesterolemia	5C80.00	Whole blood	9.43E-16	1.13E+00	2.26E+00
Gastric cancer	2B72	Gastric tissue	1.42E-01	1.04E+00	8.99E-01
Glioblastopma	2A00.00	Nervous tissue	7.42E-36	-8.94E-01	-1.02E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	8.69E-01	-7.78E-02	-4.08E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.86E-02	8.62E-01	1.03E+00
Head and neck cancer	2D42	Head and neck tissue	2.38E-04	3.42E-01	6.25E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.79E-01	-6.50E-01	-7.09E-01
Huntington's disease	8A01.10	Whole blood	7.88E-01	2.38E-02	6.64E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	2.39E-02	2.77E-01	1.04E+00
Immunodeficiency	4A00-4A20	Peripheral blood	1.53E-04	1.58E-01	1.92E+00
Influenza	1E30	Whole blood	4.28E-03	-2.05E+00	-1.50E+01
Interstitial cystitis	GC00.3	Bladder tissue	4.93E-01	-2.04E-01	-4.89E-01
Intracranial aneurysm	8B01.0	Intracranial artery	7.02E-03	2.26E-01	3.88E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.54E-02	-9.79E-02	-3.11E-01
Ischemic stroke	8B11	Peripheral blood	5.28E-01	-5.82E-02	-1.75E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.57E-03	2.63E-01	4.81E-01
Lateral sclerosis	8B60.4	Skin	4.99E-01	-3.03E-02	-1.90E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	8.47E-01	-3.16E-01	-2.64E-01
Liver cancer	2C12.0	Liver tissue	1.22E-12	-1.39E+00	-1.73E+00
Liver failure	DB99.7-DB99.8	Liver tissue	5.54E-07	-1.91E+00	-4.11E+00
Lung cancer	2C25	Lung tissue	2.85E-152	1.49E+00	3.51E+00
Lupus erythematosus	4A40	Whole blood	5.39E-07	3.59E-01	6.83E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	3.94E-01	8.33E-02	2.82E-01
Major depressive disorder	6A70-6A7Z	Whole blood	6.97E-01	1.92E-02	5.59E-02
Melanoma	2C30	Skin	2.59E-08	-1.61E+00	-1.75E+00
Multiple myeloma	2A83.1	Peripheral blood	8.11E-01	-3.27E-02	-7.79E-02
Multiple myeloma	2A83.1	Bone marrow	8.45E-22	1.40E+00	1.73E+01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.40E-01	-4.92E-01	-9.30E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.94E-02	2.00E-01	5.58E-01
Myelofibrosis	2A20.2	Whole blood	3.32E-01	1.24E-01	4.17E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.87E-01	6.56E-03	1.09E-02
Myopathy	8C70.6	Muscle tissue	2.46E-01	1.29E-01	6.84E-01
Neonatal sepsis	KA60	Whole blood	1.62E-05	2.25E-01	7.20E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	8.67E-07	1.80E+00	3.26E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.55E-01	4.94E-02	9.78E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	9.55E-01	3.18E-02	1.18E-01
Olive pollen allergy	CA08.00	Peripheral blood	4.30E-01	8.17E-02	1.74E-01
Oral cancer	2B6E	Oral tissue	2.42E-02	1.54E-01	1.14E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	1.11E-01	7.04E-01	6.87E-01
Osteoporosis	FB83.1	Bone marrow	2.93E-02	-6.93E-01	-4.88E+00
Ovarian cancer	2C73	Ovarian tissue	3.46E-05	1.38E+00	2.55E+00
Pancreatic cancer	2C10	Pancreas	2.88E-05	8.04E-01	1.49E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	2.10E-01	-7.49E-01	-8.57E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	4.23E-04	6.32E-01	1.29E+00
Pituitary cancer	2D12	Pituitary tissue	1.43E-03	9.58E-01	1.58E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.14E-02	8.76E-01	1.45E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	8.48E-01	-7.77E-02	-3.88E-01
Polycythemia vera	2A20.4	Whole blood	8.30E-04	1.36E-01	5.31E-01
Pompe disease	5C51.3	Biceps muscle	4.33E-01	1.12E-01	3.63E-01
Preterm birth	KA21.4Z	Myometrium	6.30E-01	-5.04E-02	-3.50E-01
Prostate cancer	2C82	Prostate	3.97E-06	9.35E-01	1.49E+00
Psoriasis	EA90	Skin	5.19E-01	7.44E-02	1.16E-01
Rectal cancer	2B92	Rectal colon tissue	5.21E-03	5.70E-01	2.02E+00
Renal cancer	2C90-2C91	Kidney	1.16E-02	4.64E-01	7.86E-01
Retinoblastoma	2D02.2	Uvea	1.06E-06	9.19E-01	2.60E+00
Rheumatoid arthritis	FA20	Synovial tissue	8.44E-03	4.56E-01	8.44E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.74E-01	5.22E-02	1.18E-01
Schizophrenia	6A20	Prefrontal cortex	9.59E-02	-5.00E-02	-7.61E-02
Schizophrenia	6A20	Superior temporal cortex	4.88E-01	5.25E-02	8.83E-02
Scleroderma	4A42.Z	Whole blood	1.67E-09	8.27E-01	5.17E+00
Seizure	8A60-8A6Z	Whole blood	7.61E-01	8.81E-02	2.74E-01
Sensitive skin	EK0Z	Skin	4.42E-01	4.28E-03	9.28E-03
Sepsis with septic shock	1G41	Whole blood	2.64E-01	-1.43E-02	-4.84E-02
Shwachman-Diamond syndrome	3A70.0	Bone marrow	6.72E-02	-4.08E-01	-1.35E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	2.65E-02	-1.37E-01	-4.70E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.05E-01	2.20E-01	3.81E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.71E-01	1.01E-01	1.35E+00
Skin cancer	2C30-2C3Z	Skin	1.61E-44	-1.04E+00	-1.33E+00
Thrombocythemia	3B63	Whole blood	1.94E-01	1.43E-01	5.24E-01
Thrombocytopenia	3B64	Whole blood	3.93E-01	-1.84E-01	-4.70E-01
Thyroid cancer	2D10	Thyroid	1.09E-18	3.08E-01	9.72E-01
Tibial muscular dystrophy	8C75	Muscle tissue	4.97E-04	4.48E-01	1.47E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.10E-01	-3.12E-01	-2.67E+00
Type 2 diabetes	5A11	Liver tissue	6.58E-01	-3.45E-01	-4.94E-01
Ureter cancer	2C92	Urothelium	6.43E-01	-1.10E-01	-2.91E-01
Uterine cancer	2C78	Endometrium tissue	2.86E-10	5.47E-01	5.23E-01
Vitiligo	ED63.0	Skin	9.19E-01	5.82E-02	1.16E-01